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Biomedical subjects

L Granholm

Publications and source records attributed to L Granholm.

At least 37 records · Page 2Linked to original sources
PubMed1976

Atlanto-axial fusion in rheumatoid arthritis. A new method of fixation with wire and bone cement.

Twenty-eight occipito-cervical fusions performed over the past 4 years in patients with rheumatoid arthritis are discussed. All of the patients with one exception had signs of neurological involvement preoperatively due to pressure on occipital nerve roots, spinal cord and/or vertebral arteries. A surgical technique using wire, pin and bone cement and permitting early mobilization without external fixation was used and is described in detail. The clinical results were excellent in 21 cases with an additional five patients showing improvement. One patient did not benefit from surgery and one had no symptoms preoperatively. The results are encouraging and the possibility of early mobilization (the day after surgery) is of the utmost importance for this group of patients.

Adult↗
PubMed1975

A simple technique for the determination of the ventilatory response to rising arterial CO2 tensions, suitable for patients with neurological disorders.

Patients with neurological disorders may have a reduced ventilatory response to a rising PaCO2. This is often unpredictable and may become apparent only when other complications, e.g. infections (pneumonia), occur or when the patient is subjected to general anaesthesia. This paper described a simple method suitable for screening patients who may have an impaired capacity of eliminating CO2 when stressed. Ventilatory changes were determined during the continuous recording of the CO2 concentration in end-tidal air in 20 healthy subjects, who were breathing first air and then gas mixtures containing 21% O2 and 2.5 or 5% CO2. A prediction interval with 90 and 95% probability limits was constructed for healthy individuals. The normally expected change in minute ventilation per m2 body surface area per change in PACO2 (delta versicle E/m2, l/min/delta PACO2, for this technique is also given.

Adult↗