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Biomedical subjects

L Gordon

Publications and source records attributed to L Gordon.

At least 181 records · Page 10Linked to original sources
PubMed1986

Preoperative localization of parathyroid adenomas using thallium-technetium subtraction scintigraphy.

Primary hyperparathyroidism can be diagnosed by laboratory values, yet localization of the adenomas preoperatively has always presented difficulties. Dual isotope scintigraphy with technetium Tc 99m sodium pertechnetate and thallium Tl-201 chloride has recently been used for the localization of parathyroid adenomas. In this paper, we review our experience with scintigraphy in 53 patients suspected of having hyperparathyroidism. Based on favorable results, we recommend this technique for preoperative detection of parathyroid adenomas.

Adenoma↗
PubMed1986

Posterior urethral valves: an update and review.

Here, in a comprehensive review of an important pediatric problem, the authors discuss the embryology, the clinical and radiological features, the complications and the management of posterior urethral valves.

Adult↗
PubMed1986

Vascularized fibular grafting for the treatment of congenital pseudarthrosis of the tibia.

Six patients with congenital pseudarthrosis of the tibia were treated with vascularized fibula transplantation after the abnormal pseudarthrosis site had been radically debrided. At the time of surgery, the patients' ages ranged from 18 months to 5.5 years, and follow up was from 9 months to 4.5 years. All the fibular transplants healed and the patients were all fully weight bearing in a brace 6-months postoperatively. Age at fracture or surgery, site of the fracture, or radiographic appearance were not contraindications to the use of this technique. Although three of the patients required one further operation, the short- and long-term problems have been relatively minor. This technique has proven successful in managing many resistant patients with this difficult orthopedic problem.

Child, Preschool↗
PubMed1986

Cytogenetics of human sperm: meiotic segregation in two translocation carriers.

Meiotic segregation products were studied in sperm from two men heterozygous for the reciprocal translocations t(8;15)(p22;q21) and t(3;16)(p23;q24). A total of 226 and 201 sperm complements, respectively, were analyzed. In each translocation, 63% of complements were unbalanced, and alternate and adjacent 1 percentages were similar. The 3:1 segregation frequencies produced by the two translocations were 3.5% and 5.0%.

Adult↗
PubMed1985

Chromosomes of human sperm: variability among normal individuals.

The chromosomal constitution of 2468 human sperm cells has been investigated by fusion of human sperm with hamster eggs. The overall frequency of cells with structural aberrations was 7.7%, ranging from 1.9% to 15.8%, and varying significantly among individuals. The highest frequency occurred in sperm from the oldest donor (49 years), who also had had a vasectomy reversal three years prior to sampling. The overall aneuploidy frequency was 1.7%, ranging from 0.6% to 3.1%. In nine out of ten donors from whom blood samples were available the frequency of sperm cells with structural aberrations was higher than that for lymphocytes. Two previously reported donors (Brandriff et al. 1984) were resampled after an interval of 14 and 16 months respectively, and were each found to have similar frequencies of sperm chromosome abnormalities at both sampling times. A father-son pair included in the study had several chromosome breakpoints in common, although no more frequently than unrelated individuals.

Adult↗
PubMed1985

Renal metastases from osteogenic sarcoma.

A clinically and radiographically unsuspected ossified renal metastasis from a primary osteogenic sarcoma was identified by computed tomography (CT) and radionuclide bone scan. These imaging modalities play an important adjunctive role in the evaluation and follow-up of patients with primary osteogenic sarcoma.

Adolescent↗
PubMed1985

Partial nail plate removal after digital replantation as an alternative method of venous drainage.

Partial nail plate removal, systemic anticoagulation, and the application of topical heparin to the exposed nail bed were used to provide and maintain venous drainage for 14 digital replantations in which an arterial repair but no venous repair was done ("artery only" replantation). In each case venous repair was not possible since no vein of an acceptable size could be found either because of a distal amputation level or because an avulsive or crushing injury had damaged the veins in the amputated part. The average operating time per "artery only" replantation was 2 1/2 hours. Ten of the 14 "artery only" replantations survived (71.4%). The active range of motion, sensibility, strength, activities of daily living, and hospitalization for this group of patients were comparable with replantations in which both arterial and venous anastomoses were done.

Adolescent↗
PubMed1985

Hand reconstruction for multiple amputations by double microsurgical toe transplantation.

Double microvascular toe transplant procedures were used to restore function in 16 mutilated hands. In eight hands, both opposing surfaces were reconstructed with the great toe or second toe used for the thumb and the contralateral second toe for the ulnar side of the hand. In eight hands in which the thumb was still present, two fingers were reconstructed with a second toe from each foot. All 33 transplanted toes survived. In all patients, hand function was substantially improved, with an average of 9.15 pounds of pinch strength between the transplanted opposing digits or the transplanted digit and a normal thumb. Adequate sensibility was restored. The two transplant procedures were done sequentially in six patients, while the two transplantations were performed simultaneously in 10 patients. Simultaneous reconstruction proved time- and cost-effective.

Adult↗
PubMed1985

Serial quantitative skin surface fluorescence: a new method for postoperative monitoring of vascular perfusion in revascularized digits.

Postoperative monitoring of vascular perfusion was performed in 72 revascularized/replanted digits in 40 patients. Sodium fluorescein (1.0 to 1.5 mg/kg) was administered intravenously every 2 hours for 36 to 48 hours beginning immediately after surgery. Quantitative fluorescence readings of each injured digit were obtained 10 minutes after fluorescein injection and were compared with readings from an uninjured (control) digit. A ratio between the fluorescence of the injured digit and that of the control digit was used for analysis. Viable digits had a fluorescein perfusion ratio of 86.4 +/- 16. Digits that did not survive had fluorescein perfusion ratios of 5.2 +/- 10 (p less than 0.001). The results of this study indicate that quantitative surface fluorescence assessment of revascularized/replanted digits is a minimally invasive, and reliable tool for monitoring vascular perfusion.

Child↗
PubMed1985

Functional assessment of ray transfer for central digital loss.

Nineteen patients who had ray transposition for central digital loss were evaluated retrospectively with regard to postoperative function and appearance. Pinch and grip recoveries were better in patients with small-to-ring finger transfers than in those with index-to-long finger transfers. Total average pinch recovery measured 83.3% of the nonoperated side. Total grip recovery was 80.2% of the nonoperated side. Average ranges of motion for all transferred digits were 77.6 degrees (metacarpophalangeal joint), 87.6 degrees (proximal interphalangeal joint), and 80.8 degrees (distal interphalangeal joint). Overall results judged by a five-component assessment scale were excellent.

Adolescent↗
PubMed1985

The Tweener maneuver.

A modification of standard microvascular anastomosis procedure is presented, which helps in training and improves clinical technique by conservation of motion. The speed of anastomosis is at least as rapid as the posterior wall technique on which it is based, and it has the advantage of having fewer unused penetrations of the vessel wall and better eversion of the edges.

Humans↗
PubMed1985

The extensor digitorum brevis as a muscle island flap.

The use of the extensor digitorum brevis muscle as a local muscle island flap for the coverage of the soft-tissue defects in the region of the lateral malleolus is presented. The anatomy of the muscle, the donor dissection, and the utilization of the extensor digitorum brevis muscle as a local muscle flap in the lower extremity are discussed. This flap was used successfully in a patient with a wound over the lateral malleolus and ankle.

Adult↗