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Biomedical subjects

L Gordis

Publications and source records attributed to L Gordis.

At least 55 records · Page 3Linked to original sources
PubMed1976

Psychosocial factors and the risk of myocardial infarctions in white women.

The relationship of risk of myocardial infarction (tmi) to psychosocial factors was studied retrospectively in 107 white women hospitalized with first MI's and in 218 controls hospitalized for other diseases. Meical records were abstracted and the women were interviewed. Psychosocial factors associated with MI were educational discrepancy, in which the patient ha less education than her husband, householo crowding and late birth order. Eoucational discrepancy was independently associated with MI, but household crowding and birth order seemed to act as risk factors for MI only when certain biological risk factors were also present. The findings indicate that certain psychosocial factors related to risk of MI in white males are also risk factors for MI in white females especially in association with biologic risk factors. Thus the effects of certain psychosocial factors may assume clinical importance only when interacting with an underlying disease state as indicated by the presence of major biologic risk factors.

Adult↗
PubMed1976

Tay-Sachs screening: motives for participating and knowledge of genetics and probability.

A highly-educated, socially aware group of persons presented themselves for Tay-Sachs screening having learned about it mainly from friends, newspapers, radio, and television but not from physicians or rabbis. After learning that screening was possible and deciding that it is in principle a good idea, and after discussing it with relatives and friends but not with physicians and rabbis, they presented themselves for the test. Although the participants knew that Tay-Sachs is a serious disease and that Jews are vulnerable, few of them knew much about the genetics of the disease, its frequency, or the incidence of the carrier state. This experience of screening for Tay-Sachs carriers suggests the need for physicians to learn the relation of genetics to preventive medicine, and for the public to learn more about the biology of man.

Adult↗
PubMed1976

Tay-Sachs screening: social and psychological impact.

Participants in two Tay-Sachs screening programs were generally satisifed with the organization of the tests and the results. There was no evidence of adverse impact on reproductive plans or interpersonal relations, and the respondents professed to believe in the value of screening. While the carriers discussed their condition freely with others and were no less favorable to the idea of screening than the noncarriers, about one-half of their number expressed discomfort in being told they were heterozygotes. These feelings were allayed by counseling, but there was evidence of some residual unease. It is suggested that this anxiety would be less prominent and more easily reduced if screening were done under conditions of ordinary primary medical care rather than outside the conventional system.

Adult↗
PubMed1975

Retrospective evidence favoring use of anticoagulants for myocardial infarctions.

During a state-wide retrospective study of myocardial infarction discharges from Maryland hospitals from July, 1966, through June, 1967, the relation of in-hospital case fatality rates to use of anticoagulants was examined in 1,156 patients. In patients who did not receive anticoagulants, the rate was 2.5 times that of those who did (p less than 0.0001). A large difference in case fatality rates between the anticoagulant and no-anticoagulant groups persisted when the data were analyzed by demographic and medical-care variables. When patients were classified according to clinical characteristics relating to prognosis, including arrhythmia, congestive heart failure and shock, the difference between the groups were also demonstrated. Although such a retrospective study cannot demonstrate conclusively the value of anticoagulant therapy, the data are sufficiently suggestive of a beneficial effect to warrant reopening the anticoagulant question.

Acute Disease↗
PubMed1972

Rheumatic fever.

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Adolescent↗