Biomedical subjects

L Goldberger

Publications and source records attributed to L Goldberger.

16 recordsLinked to original sources

PubMed1985

Tonic, phasic and cortical arousal in Gilles de la Tourette's syndrome.

This study explored the hypothesis that Gilles de la Tourette's syndrome involves a disturbance in arousal modulation. The experimental group consisted of 20 unmedicated subjects with the Gilles de la Tourette's syndrome, and the control group of 20 subjects with chronic medical illnesses (haemophilia, von Willebrandt's disease and diabetes). There were differences between groups in the manner in which log conductance level changed over time during sound and light habituation experiments involving mild levels of stimulation with the Gilles de la Tourette group showing less change in arousal level over trials than the control group. No group differences were found in measures of phasic arousal, rate of spontaneous fluctuations and performance on two tasks that have been related to cortical arousal. It is suggested that the slower change in log conductance level in the Gilles de la Tourette group during the sound and light habituation experiments indicates that reticular activity is more persistent in these patients.

Acoustic Stimulation↗

PubMed1982

Lateral eye-movements, field dependence and denial.

Conjugate lateral eye-movements can be used to classify some people into two distinct groups (left-movers and right-movers), who differ on various cognitive and personality variables reflecting stylistic reliance on the cognitive mode of a single hemisphere. In this study left-movers relied more heavily on denial as a defense. Field dependence tended to be related to both denial and left eye-movements by males but not females. The results are discussed in terms of a possible neuropsychological substrate for denial.

Adolescent↗

PubMed1981

Level of ego development and psychotherapy outcome in phobic patients.

forty male and 86 female phobic outpatients were randomly assigned to three treatment conditions (behaviour therapy with Imipramine: behaviour therapy with placebo; and supportive therapy with Imipramine) and seen in therapy for a 26-week period. They were initially assessed for level of ego development on Loevinger's Sentence Completion measure and evaluated for initial level of pathology and therapy outcome. A stepwise multiple regression analysis, performed separately for the female and male groups, yielded results as follows: (1) patients at the preconformist level improved significantly less than the patients at the other levels; (2) an interaction between the use of medication and level of ego development was also found, with postconformist patients reporting the least benefit from the drug. These findings were significant only for the female patients.

Adult↗

PubMed1979

Field dependence and short-term memory.

This study examined the relationship between field dependence and short-term memory. It was predicted that relatively field-independent individuals would perform better on short-term memory tests in which a large amount of interference is assumed to be present than would individuals who are more field-dependent. Subjects' appraisals of their own attentional facility, as well as their thoughts and feelings about the experimental tasks, were also elicited, and were looked at in terms of their relationship to field dependence and short-term memory.

Adolescent↗

PubMed1978

Relationship between agoraphobia and field dependence.

In recent years agoraphobia has been viewed by clinicians as etiologically distinct from other phobic disorders, with conflicts over the developmentally early issue of separation and individuation (self-other differentiation) playing a central role. In an effort to adduce quantitative evidence for this clinical observation, three groups of phobic patients (totaling 166 outpatients in all) were distinguished on the basis of their symptomatology (agoraphobia, simple phobias, and mixed phobias) and were individually administered the Group Embedded Figures Test as a measure of field dependence, a cognitive style dimension that according to Witkin is, at least in part, a manifestation of self-other differentiation. A one-way analysis of variance, performed separately for men and women for differences among the three phobic groups on field dependence, showed significance (rho less than .05) for the females, with the famale agoraphobic being more field dependent than the female simple phobic groups, but not for the males. Implications for the understanding of agoraphobia are discussed.

Adult↗

PubMed1977

Angiographic aspects of experimental nonocclusive intestinal ischemic injury.

An experiment was designed to fulfill the following aims: (1) to develop a model of nonocclusive intestinal ischemic injury compatible with survival for several days; (2) to determine the accuracy of angiography in diagnosing the presence and extent of intestinal ischemic injury; and (3) to determine the therapeutic and diagnostic value of intraarterial papaverine infusion. Experimental shock models were developed in the dog, and efficacy of the hypovolemic and normovolemic models was confirmed by gross and histologic evidence of intestinal injury in surviving dogs. No reliable angiographic signs of intestinal mucosal injury could be elicited. Angiographic abnormalities associated with the experiment were attributable to the shock itself and disappeared with the relief of shock. Infusion of papaverine into the superior mesenteric artery within 2 hr of the onset of shock prevented or ameliorated intestinal injury.

Angiography↗

PubMed1976

Immune-related renal vein thrombosis in a renal allograft.

A patient developed a renal venous thrombosis 15 months after renal transplantation. In contrast to other cases described in the literature, the thrombosis was not related to vascular surgical trauma, but was immune-complex mediated. The patient's renal function stabilized and the nephrotic syndrome improved over 18 months follow-up during continuous oral anticoagulant therapy.

Adult↗

PubMed1975

Catheter exchange in tortuous vessels during selective cerebral angiography.

Inability to advance double-curved catheters beyond the origin of tortuous arch vessels in a common problem in femorocerebral angiography in the aged or hypertensive patient. The authors describe a simple technique involving the use of an exchange guide wire and straight catheter which has proved to be safe and successful in such circumstances.

Catheterization↗

PubMed1972