Search PubMed⌕ Search

Biomedical subjects

L Goldberg

Publications and source records attributed to L Goldberg.

195 records · Page 11Linked to original sources
PubMedDate not supplied

Myocardial viability--mechanisms of reversible myocardial dysfunction and diagnosis in coronary artery disease.

The natural history of ischaemic myocardium and numerous revascularisation studies have proved that it is clinically important to distinguish viable but dysfunctional myocardium from irreversibly injured muscle in patients with coronary disease. A large variety of invasive and non-invasive methodologies are available for the detection of myocardial viability. This review focuses on the value and limitations of the current diagnostic approach to the recognition of stunned and hibernating myocardium in the light of the current understanding of their pathophysiological mechanisms.

Coronary Artery Disease↗
PubMedDate not supplied

Triscuspid annular dilatation causing severe valvular incompetence and associated with dystrophic calcification of the left ventricular myocardium.

We report on a case of severe tricuspid regurgitation (TR) in a young patient with no history of chest trauma and with an anatomically normal tricuspid valve (TV) apparatus and a dilated TV annulus associated with dystrophic calcification of the left ventricular myocardium. The possibility of congenital pathology as well as the possibility of this being a limited inflammatory or restrictive myocardial disease is discussed.

Adult↗
PubMedDate not supplied

Echocardiographic evaluation of bileaflet mechanical prosthetic valves.

In this article we review the value and pitfalls of the echocardiographic evaluation of bileaflet prosthetic valves commonly used at present. The basic physics of echocardiography of these prosthetic valves is presented, and practical guidelines for evaluation of prosthetic valves are formalised.

Aortic Valve↗
PubMedDate not supplied

Congenital left ventricular aneurysm in an adult.

A rare case of idiopathic massive apical ventricular aneurysm in a young man is reviewed. Secondary infection was present in the aneurysm. No features of left ventricular failure were observed.

Adult↗
PubMedDate not supplied

Acute myocarditis in a patient with eosinophilia and pulmonary infiltrates.

This is a case of nectrotising myopericarditis complicated with an acute apical left ventricular aneurysm in a young patient with the history of bronchial asthma and recurrent eosinophilia. Prompt clinical improvement coinciding with normalisation of the blood count in response to steroids was observed. Possible aetiology of hypereosinophilia is discussed.

Acute Disease↗
PubMedDate not supplied

Platelet glycoprotein IIb/IIIa receptor blockade with integrilin (eptifibatide) for early postinfarction angina in a patient with coronary arterial ectasia.

A middle-aged male with multivessel proximal coronary ectasia presented with thrombosis-related acute myocardial infarction and early postinfarct angina, and was successfully treated with a combination of intravenous integrilin (eptifibatide) and unfractionated heparin. The possible aetiology, prognosis and available management strategies are discussed.

Adult↗
PubMedDate not supplied

Chronic idiopathic effusive pericarditis in a patient with 'cor pulmonale'.

Chronic idiopathic pericarditis is a diagnosis of exclusion that is estimated to occur in 3.5% of primary pericardial disease. It is possible that many of these cases are secondary to unrecognised viral infections. The natural history is variable and treatment should be individualised, although chronic colchicines administration may hold promise as a newer therapeutic modality in symptomatic recurrent pericarditis. This case presentation illustrates the diagnostic and therapeutic difficulties that may arise in such patients.

Adult↗
PubMedDate not supplied

Transoesophageal atrial pacing stress echocardiography in coronary artery disease: role, principles and methodology.

This article reviews the physiology and methodology of transoesophageal atrial pacing stress echocardiography (TAPSE) and clarifies its place among the other stress modalities. TAPSE correlates well with myocardial perfusion stress scintigraphy and coronary angiography and is a simple and safe diagnostic option for patients with suspected or known CAD, including those with recent myocardial infarction. Furthermore, the results of TAPSE have prognostic significance in patients with uncomplicated MI. Although, it is a highly feasible and safe technique, the cardiologist should be directly involved in the procedure and the personnel must be well trained in a large number of tests, as for any other stress echocardiographic modalities.

Cardiac Pacing, Artificial↗
PubMedDate not supplied

A two-year, single-group experience with rotational atherectomy.

Rotational atherectomy was introduced with a view to approaching percutaneously, cases that were suboptimal or unsuitable for conventional percutaneous transluminal coronary angioplasty (PTCA). In this article we present our findings for a period of two years starting in April 2001, when 60 procedures were performed on 54 patients. We found the procedure to be successful in B2 and C type lesions. It is our opinion that the lower burr-to-artery ratio used in our cases was significantly beneficial in decreasing immediate complications related to the procedure. Complimentary PTCA and stenting improved the angiographic end result. Using this strategy, we have achieved very acceptable clinical results.

Aged↗
PubMedDate not supplied

The value of cerebrospinal fluid cytology in the early diagnosis of metasttatic retinoblastoma.

The cytomorphologic features of exfoliated retinoblastoma cells in CSF processed by a simple micropore filter technique has been described. The role of CSF cytology in the early identification of metastatic retinoblastoma cells, with its influence on treatment and prognosis, is stressed. Retinoblastoma cells in CSF are characteristically small with scanty or absent cytoplasm and hyperchromatic irregular nuclei which tend to be moulded. These cells generally occur singly or aggregated into clusters of various sizes but are seldom seen in typical rosette formation.

Brain Neoplasms↗