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Biomedical subjects

L Giarelli

Publications and source records attributed to L Giarelli.

At least 55 records · Page 3Linked to original sources
PubMed1980

Observations on the epidemiology of oesophageal carcinoma in the province of Trieste.

After describing the enormous variation in incidence of oesophageal carcinoma in different populations, the authors report data on the incidence of carcinoma of the oesophagus in the province of Trieste, Italy. There is a high incidence in men, this being among the highest in the world, excluding areas with so-called 'endemic' disease. On the other hand, the incidence in women is low, even compared to other European regions. The epidemiological data reveal in particular that, in the province of Trieste, carcinoma of the oesophagus affects predominantly young and middle aged men. This may be related to high alcohol and tobacco consumption.

Adult↗
PubMed1979

Giant-cell pneumonia and lung tumorlets in a leukemic four-year-old child.

The authors report a case of a 4-year-old child whose death resulted from acute lymphoblastic leukemia (ALL) and giant-cell pneumonia. Typical lung tumorlets were occasionally observed. On electron microscopy study it was possible to demonstrate a large number of neurosecretory granules in the tumorlet's cells, identical to those present in Kulchitsky's cells. These studies suggest the occurrence of an abnormal immunitary process.

Child, Preschool↗
PubMed1978

[Pathological observations on patients carrying pacemakers and clinical consequences. Reports of 105 observed cases (author's transl)].

In subjects carrying pacemakers, the catheter-electrode can induce, over a period of time, specific modifications at the level of the veins and the heart. The organism reacts to extraneous bodies with adhesive and sometimes thrombotic phenomena. The latter can occasionally be the cause of a pulmonary embolism (8 cases out of 105) or more rarely, the seat of a mycotic infection (one case). In the casuistry are included two cases of the complete perforation of the right ventricle (one of which was fatal) and four cases of partial perforation; in another subject a papillary muscle was perforated. Finally, one case of endocarditis was noted, the so called traumatic type, of the tricuspid valve.

Cardiovascular System↗
PubMed1977

14 cases of cavernous degeneration of the optic nerve.

After a brief bibliographical introduction the author's report on 14 cases of cavernous degeneration of the optic nerve, based upon the study of 1,831 autoptic cases. All the subjects examined showed lesions of a senile degenerative type in the vessels afferent to the retro-laminar segment of the optic nerve. The pathogenetic mechanism of the lesion under examination seems therefore to be attributable to ischaemic cause of a chronic type. Myopia and glaucoma, if present, would also seem to contribute, as they cause disorders of the blood system in this region.

Aged↗
PubMed1975

[Pathogenesis of cerebral hemorrhage considered in the light of objective lesions in the arteries of the brain (in 226 cases studied by autopsy)].

Conclusions drawn from the post-mortem examination of 226 subjects who died of cerebral haemorrhage are presented. There were slightly more women than men (53%) in the series. Arterial hypertension (68%) was the main cause of death, while renal disease, leukaemia, angioma of the pons, and embolism due to bacterial endocarditis were also observed. The most frequently noted sites are listed. Since cerebral haemorrhage follows the rupture of one or more already damaged deep arteries, as assessment was made of the part played by vascular lesions. 13 cases due to leukaemia and 35 to rupture of aneurysms of the polygon of Willis were discarded. In only 20 cases out of 138 in which convincing microscopic evidence of the vascular situation could be obtained was there an absence of significant alterations. The remaining cases consisted of serious hyalinosis (56%), fibrinoid necrosis (13%), and siderocalciosis (12%). An account is also given of the special pathogenetic conditions applicable to cerebral haemorrhage associated wtih serious gastrointestinal haemorrhage or recent myocardial infarct.

Brain Neoplasms↗