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Biomedical subjects

L Gang

Publications and source records attributed to L Gang.

4 recordsLinked to original sources

Hypernuclear fine structure in (9)(lambda)Be.

With a germanium detector array (Hyperball), we observed two gamma-ray peaks corresponding to the two transitions (5/2(+)-->1/2(+) and 3/2(+)-->1/2(+)) in the (9)(Lambda)Be hypernucleus which was produced by the 9Be(K-,pi(-)) reaction. The energies of the gamma rays are 3029 +/- 2 +/- 1 keV and 3060 +/- 2 +/- 1 keV. The energy difference was measured to be 31.4(+2.5)(-3.6) keV, which indicates a very small Lambda-spin-dependent spin-orbit force between a Lambda and a nucleon. This is the smallest level splitting by far ever measured in a hypernucleus.

Journal Article↗

Optimizing culture of Chlamydia pneumoniae by using multiple centrifugations.

Three methods for the recovery of Chlamydia pneumoniae from spiked nasopharyngeal and blood specimens, including extended culture and additional centrifugations, were compared. Additional centrifugations and a 7-day culture time resulted in a 500- to 5, 000-fold increase in the number of detectable inclusion-forming units.

Cells, Cultured↗

A novel gene: sawD related to the differentiation of streptomyces ansochromogenes.

A 1.3 kb DNA fragment was cloned from a total DNA library of Streptomyces ansochromogenes using Southern hybridization. Nucleotide sequencing analysis indicated that the 1320 bp DNA fragment contained a complete open reading frame (ORF). In search of databases, the deduced product of ORF containing 213 amino acids is homologous to the serine protease of Caulobacter cresceatus, and a conserved serine-catalytic active site (GPSAG) exists. The gene was designated as sawD. The function of this gene was studied with the strategy of gene disruption, and the result showed that the sawD may be related to sporulation and especially to the spore septation in Streptomyces ansochromogenes. The preliminary result indicated that sawD mutant could produce abundant pigment in contrast with the wild type, it seems that sawD gene may be involved in pigment biosynthesis, and this gene is also dispensable for biosynthesis of nikkomycin in Streptomyces ansochromogenes.

Amino Acid Sequence↗

[Changes of the arterial baroreflex sensitivity in one-kidney Grollman hypertensive rats].

The objective of this study was to investigate the changes of arterial baroreflex sensitivity (ABS) in one-kidney Grollman hypertensive rats. The blood pressure was altered with phenylephrine or sodium nitroprusside. Mean arterial pressure (MAP) and pulse interval were recorded simultaneously and the MAP-pulse interval regression line was constructed. All rats were divided into three groups: Grollman-operation group, sham-operated group and normal group. ABS was determined at the 3rd week after operation. The results were as follows: The ABS of the Grollman hypertensive group was significantly lower than that of the sham-operated group (P less than 0.01). After i.v.c. injection of 150 micrograms captopril the MAP of both groups are lowered, but more significantly in Grollman than in the sham-operated group (P less than 0.05, at 35 min after injection). From 35 to 60 min after injection, the MAP of the sham-operated group has practically reached a steady level while that of the Grollman group still shows significant tendency of decline. At 60th min, the ABS of the hypertensive was significantly increased than that measured 60 min before injection (P less than 0.05), while similar measurements for the sham-operated group showed only a slight or much less significant increase. MAP was increased and ABS was decreased by i.v.c. injection of 8 micrograms angiotension II in the normal group. The results of the present investigation indicate that ABS decreases during the development of one-kidney Grollman hypertensive rats, and that this change appears to be related to the increased concentration of angiotension II in the brain.

Angiotensin II↗