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Biomedical subjects

L Galanti

Publications and source records attributed to L Galanti.

21 records · Page 2Linked to original sources

Cytologic screening for cervical cancer in the Florence District.

During the years 1970-1978, 213,575 women living in the Florence District had at least one cytologic smear. The overall incidence ratios were: dysplasia 1.09 0/00, carcinoma "in situ" 1.25 0/00, invasive carcinoma 1.01 0/00. Age of the women attending the service, and incidence ratios according to age groups are examined. Incidence ratios in women who had previous negative smears are calculated; these values seem to fit well with a "false negative model". These results are compared with those reported by other authors, and indications for a new kind of program are suggested.

Adolescent↗

Plasma atrial natriuretic factor and catecholamines before and during excision of pheochromocytoma.

We studied changes of atrial natriuretic factor (ANF) and catecholamines in three patients with pheochromocytoma occurring in the familial syndrome of multiple endocrine neoplasia type IIa. Previous studies have suggested a stimulating effect of catecholamines on ANF release. In pheochromocytoma, we observed normal basal ANF levels despite increased catecholamine secretion. In contrast, a rise in plasma ANF was observed when a hypertensive paroxysm occurred. Also during surgery, dissection of pheochromocytoma led to a rise in plasma ANF and catecholamines associated with an increase in blood pressure (in the 3 cases) and in pulmonary artery pressure (in 2 cases). We concluded that chronic elevation of basal catecholamines are without effect on plasma ANF but that manipulation of pheochromocytoma leads to a stimulation of ANF release, possibly mediated by either a direct effect of endogenously released catecholamines and/or an increase in atrial pressure.

Adrenal Gland Neoplasms↗