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Biomedical subjects

L G Upton

Publications and source records attributed to L G Upton.

At least 19 recordsLinked to original sources

The treatment of temporomandibular joint internal derangements using a modified open condylotomy: a preliminary report.

A modified open condylotomy was used to treat 44 patients who presented with painful temporomandibular joints, and in whom the clinical and arthrographic findings were indicative of disc displacement. A total of 64 joints (20 bilateral) were operated on. Postoperatively, the patients showed an overall improvement in their functional symptoms. Ninety-one percent of patients had improvement in clicking and popping, and 96% reported decrease in locking. Complaints related to pain and headache were improved 85% and 95%, respectively. The modified technique, as well as the anatomic basis for its use, are discussed.

Adolescent

Surgically and nonsurgically treated temporomandibular joint patient responses to active and passive nonsurgical therapies.

A retrospective study was performed to evaluate the subjective responses of surgically and nonsurgically treated temporomandibular joint (TMJ) patients to active nonsurgical therapies and the combination of active and passive nonsurgical therapies. The results showed that for patients who had TMJ surgery, there was a statistically significant improvement in symptomatology rating in those receiving a combination of active plus passive therapies, compared to active therapies alone. For the nonsurgical patients, there was no statistically significant difference in symptomatology rating scores between active only and the combination of active and passive treatment modalities.

Adult

A study of the utility of measuring mandibular mobility by means of the interincisal dimension.

The purpose of this investigation was to determine the reliability of using the interincisal dimension as a measure of mandibular range of motion. Thirty patients who underwent mandibular advancement and 15 patients who underwent mandibular setback were included in this study. Preoperatively, a lateral cephalogram in centric relation and a second cephalogram with the mandible at maximum voluntary gape were obtained. Immediately following surgery, another centric relation cephalogram was obtained. A composite tracing of the two preoperative tracings was made to show how the mandible changed in position from the closed-mouth to the open-mouth radiographs. The proximal segment (ramus) of the postoperative cephalogram was then superimposed on the open-mouth mandibular ramus, and the distal segment of the postoperative mandible was drawn. This composite produced a tracing of what the postoperative maximal gape cephalogram would be if the same amount of condylar rotation and translation as in the preoperative tracing had occurred. The preoperative interincisal dimension was recorded on the composite tracings (factoring in any overbite or openbite) as was the would-be postoperative interincisal dimension. These measures were compared using the paired t test and Pearson's correlations to determine if there were any significant differences between them. The results showed that the interincisal dimension is a fairly reliable measure of mandibular mobility even when the length of the mandible is altered with surgery.

Cephalometry

Particulate allogeneic bone grafts into maxillary alveolar clefts in humans: a preliminary report.

The purpose of this study was to determine the ability of particulate allogeneic bone graft to adequately bridge unilateral maxillary alveolar clefts in humans. Twenty patients with unilateral alveolar clefts and oronasal fistula underwent alveolar cleft grafting with a clinically appropriate amount of particulate allogeneic bone. The grafted cleft area was followed radiographically for three to six months postsurgery. Although it was difficult to quantitate, it was both clinically and radiographically apparent at three months that bone bridging and filling of the cleft had occurred in 100% of the cases. From this study, it appears that allogeneic bone is a viable alternative for repairing alveolar clefts and that its use has a significant benefit to the patient by eliminating the morbidity of a second operative site.

Adolescent

Evaluation of the regenerative capacity of the inferior alveolar nerve following surgical trauma.

The fate of 52 nerves where there was altered sensation following sagittal ramus osteotomy and mandibular advancement, and 15 nerves where this occurred after third molar removal were evaluated through questionnaires involving both subjective and objective components. The study covered an interval between six and 54.5 months, with a mean of 31.9 months. Of the altered nerves from sagittal ramus osteotomy, 53.8% returned to normal, while 60% returned to normal in the third molar group. No correlation was found between terms used by the patient to describe the altered sensation and prognosis of nerve regeneration. In addition, correlation was not noted between the topographic distribution of altered sensation and the prognosis or residual deficit. No significant difference was found between the two methods of assessing nerve regeneration. A relationship was noted between age of the patient and increasing incidence of persistent altered sensation.

Adult

Double-blind evaluation of etodolac (200 mg, 400 mg) compared with zomepirac (100 mg) and placebo on third molar extraction pain.

This controlled, single dose study has demonstrated that compared with placebo, substantial analgesia is obtained with 200 and 400 mg doses of etodolac. The analgesic effects of both doses of etodolac were not notably different from each other or significantly different from zomepirac, a proven analgesic. With respect to safety, both doses of etodolac were well tolerated, with no reports of serious or dose related adverse side effects.

Acetates

Major maxillomandibular malrelations and temporomandibular joint pain-dysfunction.

A retrospective questionnaire survey of 102 patients who underwent orthognathic surgery for maxillomandibular disharmonies assessed the incidence of TMJ pain-dysfunction in both pretreatment and posttreatment phases. While retrospective questionnaire studies have obvious limitations, the following conclusions deserve consideration. The incidence of TMJ pain-dysfunction symptoms found in this patient population appears to be higher than the incidence of those symptoms reported in previous epidemiologic studies of general populations which involved subjective symptoms alone. Maxillomandibular disharmonies may be an important etiologic factor in the development of TMJ pain-dysfunction. Surgical correction of the disharmony in a significant percent of patients with maxillomandibular disharmonies and concomitant TMJ pain-dysfunction may alleviate or improve the TMJ pain-dysfunction symptoms. There is a possibility that patients may develop TMJ pain-dysfunction symptoms after orthognathic surgery.

Female

An unusual complication after excision of a recurrent mucocele of the anterior lingual gland.

A case report of a recurrent mucous extravasation phenomenon in the anterior lingual gland is presented. Multiple surgical procedures were necessary to eradicate the lesion. Alginate impression material was used during one of the surgical procedures to aid in defining the margins of the lesion. A foreign-body reaction arose in the tongue as a result of residual alginate within the tissues, necessitating further surgery. The use of this technique cannot be recommended in areas where extension into surrounding tissue planes is possible.

Adult

Advantages of long-acting local anesthesia using etidocaine hydrochloride.

A double-blind clinical evaluation comparing 1% etidocaine with 1/200,000 epinephrine and 2% lidocaine with 1/100,000 epinephrine for third molar surgery was done on 42 patients. Aspects of long-acting and short-acting local anesthesia were compared, including time of onset, potency, regression, duration, and appraisal by the patient. The preference of patients and the experience of postoperative pain are emphasized.

Acetanilides

Evaluation of sedative/analgesic combination for postoperative pain.

Current pain concepts suggest a dual role in pain perception. Both motivational, effective, and somatosensory components are noted. Pain affects the patient's psyche and, conversely, the patient's state of mind modifies pain perception. Consequently, it might be expected that a sedative/analgesic combination might be more effective than either the sedative or the analgesic alone in controlling pain. A clinical study was carried out to compare a promethazine-A.P.C. combination with promethazine and A.P.C. alone. One hundred forty-nine patients undergoing third molar removal were studied, with each patient serving as his own control. The results indicated a significant difference between the promethazine-A.P.C. combination and prometazine alone or Phenergan alone. No significant difference was noted between the promethazine-A.P.C. combination and A.P.C. alone.

Anxiety

Neurofibrosarcoma of the mandible.

A case has been reported to illustrate the apparent transition of a neurofibroma into a neurofibrosarcoma. Biopsy of the inferior alveolar nerve, proximal to the lesion, was used to determine the extent of tumor extension. En block excision of the tumor was performed. The patient has been without evidence of recurrence for approximatley 3 1/2 years. Bone graft reconstruction has been completed and full function has been restored to the mandible.

Adult