Biomedical subjects
L G Stoliarova
Publications and source records attributed to L G Stoliarova.
[Qualification requirements for physician-bacteriologists].
The authors present the qualification requirements to laboratory physicians specialized in bacteriology. The knowledge and skills of a bacteriologist, necessary for his organizations, methodologic, prophylactic, and diagnostic activities, are listed.
[Antibiotic resistance of Shigella isolated in the Kara-Kalpak A.S.S.R. 1987-1988].
Sensitivity of Shigella spp. isolated in one of the hospitals of Nukus within 1987-1988 and earlier in 1977 and 1985 was studied. S. flexneri 1-5 remained the main causative agents of dysentery on the territory. However, beginning from 1987 there were registered cases of dysentery caused by S. dysenteriae 1. The isolates were most sensitive to cefotaxime, cephaloridine, polymyxin B and gentamicin. The majority of the isolates were resistant to tetracycline, levomycetin (chloramphenicol) and streptomycin. No significant changes in the sensitivity levels of the strains isolated in 1987-1988 as compared to those isolated in 1985 were observed.
[Prevention of contractures in post-stroke arthropathies].
Arthropathies develop in 15-20% of post-stroke paresis patients. A complex of rehabilitative measures including physical therapy (transcutaneous stimulation analgesia, heating etc.), kinesitherapy and anabolic hormones can prevent contractures if applied at the early rehabilitative stage.
[Experience using selective monoamine oxidase inhibitors in treating parkinsonism patients].
MAO B selective inhibitor was given to parkinsonism patients for several months. Positive effect was found in half of the patients irrespective of their age, time of the disease onset and its severity. The drug proved most effective in bradykinesia. Its use is most expedient in combination with L-DOPA-containing drugs which prolong the effect and reduced diurnal shifts in the patients' conditions. Side effects are seldom observed and usually weak.
[Rehabilitation of patients who have had a stroke].
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[Stabilizing effect of hydroxybenzimidazole and its derivatives on biological membranes during activation of lipid peroxidation].
Inhibition of lipid peroxidation (LPO) by oxybenzimidazole (OBI) and its derivatives--alkyloxybenzimidazole (AOBI) and alkylethoxybenzimidazole (AEBI) was studied in liver microsomes and brain synaptosomes. It has been shown that both OBI and AOBI strongly inhibit LPO in microsomes and not synaptosomes. AEBI failed to inhibit LPO in microsomes. AOBI is more potent than OBI both in ascorbate- and NADPH-dependent LPO of microsomes. An antioxidant effect of both compounds is more marked in ascorbate-dependent LPO. The investigation of the possible use of AOBI for the protection of liver membranes in various pathological conditions associated with LPO activation seems promising.
[Experience with the use of parlodel in the treatment of Parkinson patients].
The dopamine agonist parlodel was given to 42 patients with parkinsonism for several months. The drug proved effective in more than one-third of the patients. Different side-effects were observed in almost half of the patients. Parlodel may be used alone in mild cases but generally it is used as an adjunct to L-DOPA therapy. The optimum dose of parlodel is individual and varies within a wide range.
[Speech disorders with localization of the vascular focus in deep structures of the dominant hemisphere of the brain].
The authors present the clinical picture and time-course of aphasia (A) in 25 patients, 18 of whom had had hemorrhagic and 7 ischemic stroke. Dynamic neuropsychological examination and computer-aided tomography (CT) of the brain were carried out. The development of marked and stable A was observed in 20% of the cases. The frequency was higher with brain infarction and lower with cerebral hemorrhage. In 3 cases of deep localization of brain infarction the authors describe a peculiar speech syndrome not observed in other aphasic patients. It was characterized by (1) intactness of mechanisms underlying the realization of speech despite the presence of marked aphasia, (2) greater variability and inconsistence of results of implementation by patients of speech tasks. Clinico-CT correlations gave grounds for explaining the rate and degree of speech recovery, as well as the nature of A with the predominant lesion to some or other deep structures of the left hemisphere of the brain.
[Relation between features of the recovery of motor functions in patients with ischemic strokes and the site and extent of lesion focus].
The nature and degree of motor disorders, the degree and rate of recovery were shown to be more dependent on the localization than on the size of the cerebral infarction specified by computer-aided tomography of the drain. Localization of infarct in the posterior femur of the internal capsule proved the least favourable with regard to the recovery of motor functions.
[Prospects for the development of scientific research in the area of rehabilitative treatment of post-infarct patients].
Three basic areas of research on the rehabilitation treatment of cerebral stroke survivors are reviewed: (1) the identification of factors affecting the recovery of impaired functions; (2) the development of new and improvement of the conventional methods of rehabilitation therapy; (3) the elaboration and perfection of principles of rehabilitation treatment organization.
[Recovery of disordered motor functions in patients with brain hemorrhages in relation to the localization of the focus of the lesion].
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[Scoring system for the status of motor functions in patients with post-stroke paralyses].
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[Features of speech dynamics in patients with different variants of motor aphasia in stroke].
Results of studying the peculiarities of speech restoration in patients with dynamic, efferent, afferent, and mixed motor aphasia are presented. These peculiarities were found to depend on the gravity of the speech disorder, time of the beginning and duration of the logopedic treatment, methods of the restorative training, relation between the impaired and preserved sides of the speech function. The studies of the peculiarities of the speech restoration process in various forms of motor aphasia have demonstrated that restorative training is necessary, has good prospects, and may contribute to a substantial social readaptation of the patients.
[Recovery of motor disorders following stroke].
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[Speech syndrome and its course in patients who have sustained an ischemic stroke (clinico-tomographic study)].
Clinical and tomographic examinations of 40 patients with aphasia developed after an ischemic stroke were carried out. In more than half of them no correlation between the aphasia gravity and character on the one hand, and the size and localization of the ischemic focus (or foci) in the brain on the other was noted. With similar character and gravity of the speech disorder the size and localization of the ischemic foci may be different, ad vice versa. It has been shown that the interrelations between the focal pathology of the brain and the character and gravity of speech disorders are very complicated. One should take into consideration the possibility of individual organization of the speech functions, the degree of the speech activity automatism before the disease, and the state of the cerebrovascular system as a whole.
[Rehabilitation of the motor disturbances in poststroke lesions of the left and right hemispheres].
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