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Biomedical subjects

L G Siegel

Publications and source records attributed to L G Siegel.

15 recordsLinked to original sources
PubMed1989

The computerized audiology clinic.

Computer-assisted audiologic testing is undergoing a transition from laboratory settings to audiology clinics, resulting in increased accuracy, efficiency, and sophistication in the evaluation and treatment of patients. The computerized clinic also offers superior information storage and analysis capabilities and increasingly significant economic advantages. Implementation of new test techniques with software modification, rather than expensive new electronic instrumentation, is an advantage unique to the computer-based audiologic system. Decisions regarding the selection from a variety of system architecture designs and human interface schemes are critically important and unique to this new technology. The replacement of traditional audiometric instruments with computer-controlled systems will accelerate as system sophistication increases and cost continues to decrease.

Ambulatory Care Facilities↗
PubMed1986

Plastic bronchitis.

Plastic bronchitis is an uncommon disease of children characterized by the formation of long, branching bronchial casts. Of three children with such bronchial casts, one developed status asthmaticus and coughed out a complete cast of the tracheobronchial tree. One other child also had a course of desensitization for allergies. Two children presented with what was originally thought to be pneumonitis, but when chest x-rays were taken, one child was suspected of having an inhaled foreign body, and the other had complete opacification of one lung. When these two children were examined bronchoscopically the tracheobronchial tree was found to be filled with white, cheesy material. This material was extremely hard to remove bronchoscopically as the material was too soft to grab with forceps but too thick to suction. The material extended all the way down into the tertiary bronchi, and in one child multiple bronchoscopies were necessary to remove this material, and even so he developed bronchiectasis. The pathologic examination of these casts showed layers of inspissated mucus and inflammatory cells.

Adolescent↗
PubMed1983

Bacterial tracheitis.

During a two-year period, 17 children were brought to the St Paul Children's Hospital with the clinical features of croup, unresponsive to conventional therapy; 12 of these were seen during a two-month outbreak of parainfluenza virus type 1 that occurred in the community. Bronchoscopy showed copious purulent tracheal secretions. Cultures of transbronchoscopic aspirates were positive for bacterial organisms, the most common being Staphylococcus aureus (six of 17) and alpha-hemolytic Streptococcus (seven of 17). Four of these children, all treated conservatively with observation and/or endotracheal intubation, suffered a cardiorespiratory arrest, and two of them died. In contrast, one of 13 children who underwent tracheostomy died. Bacterial tracheitis clinically resembles viral croup, but carries a significant morbidity and mortality. Bronchoscopy documenting the presence of copious endotracheal pus and prompt tracheostomy may reduce the complications of this disease.

Bronchoscopy↗
PubMed1982

Epiglottitis.

Explore the source record for details and available documents.

Child↗
PubMed1981

Christmas bow pins: a potential inhaled foreign body made safer by industrial modifications.

The 3M Company (Minnesota Mining and Manufacturing Company) has produced about three billion plastic Christmas bow pins over 20 years. When it was reported that inhalation of these pins had resulted in two deaths, the company sought otolaryngologic consultation to suggest design modifications which would decrease the risk of aspiration asphyxia. The circular base of the bow pin was modified into the form of a cross so that it would not completely obstruct the airway. Barium was added to render the bow pin radiopaque. When the unmodified bow pin was inserted into the larynx of ten cats, six died. The modified pin caused no deaths in nine cats. We regard this as an example of responsible cooperation between industry and medicine.

Accidents, Home↗
PubMed1976

Reduction of mandibular fractures.

The decision to reduce a mandibular fracture by closed or open intraoral or extraoral techniques is not simple and depends upon multiple factors. That decision can be made only by the surgeon who understands the nature of the injury, the forces acting upon the injury site, and the relationship of the injury to other mandibular structures and to surrounding tissue. Other factors to consider include dentition and occlusion and an understanding of the healing processes, including the effects of concurrent disease and associated and distant trauma.

First Aid↗
PubMed1975

Fractionation of protein carried by axoplasmic transport. II. Comparison in the rat of proteins carried to the optic relay nuclei.

Proteins carried in the fast (200 mm/day) axoplasmic flow of retinal ganglion cells in albino rats were labeled with intraocular injections of radioactive L-methionine. Transported proteins which accumulated in the lateral geniculate nuclei (LGN) and superior colliculi (SC) 4 1/2 hours after injection were extracted with media of increasing solubilizing power. Over 70 percent of the transported material is soluble only in media possessing detergents such as Triton X-100 and sodium dodecyl sulfate. Specific activities of the transported proteins exceeded 7000 dpm/mg. With specific activities this high, further fractionation could be carried out under conditions of high resolution. Separations of solubilized proteins on polyacrylamide gels, either with or without detergents, showed that a large number (60-100) of polypeptides are transported. Using a double labeling procedure which employed L-[35S]methionine and L-[methyl-3H]methionine, material transported to the LGN was compared with that transported to the SC. No statistically significant differences were seen in the polypeptides transported by the retinal ganglion cells to the two major optic relay nuclei.

Animals↗
PubMedDate not supplied

Claudication on mastication following bilateral external carotid ligation.

Ligation of both external carotid arteries to control epistaxis can produce a decrease in the blood supply of the muscles of mastication sufficient to cause pain typical of claudication while chewing. We report 3 cases of this complication. We advocate that this procedure be used only in special circumstances.

Adult↗