[Development of medical technologies for emergency medical services].
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Biomedical subjects
Publications and source records attributed to L G Kostomarova.
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Assay of the clinical course of poisoning with acetic acid, dichloroethane, carbophos, chlorophos, phenobarbital and sodium etaminal in 2538 patients made it possible to define, with the use of the probit analysis, the 25, 50, 75 and 95% concentration thresholds of the lethality in acute poisonings with acetic acid, carbophos and dichloroethane. It was established that under exposure to the toxic substances undergoing different chemical changes in the body, the increase of the lethality risk varied in different age groups. The differences in the structure of outcomes in patients of different age groups formed the basis for making up a classification of the toxicity of the chemical compounds. The differences revealed require a differential approach to the determination of the scope of intensive care of poisonings in terms of the age-associated features.
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A new method of sorptional detoxication (hemosorption) was used in the treatment of schizophrenia. The method consisted in blood perfusion through activated carbon. In all, 13 sessions of hemosorption were performed in 9 patients with different forms of schizophrenia. The preliminary data indicate that detoxicational hemosorption facilitates rapid disappearance of psychotic symptomatology, permits the doses of psychopharmacological drugs and the duration of hospital treatment to be significantly reduced.
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