Search PubMed⌕ Search

Biomedical subjects

L G Goodwin

Publications and source records attributed to L G Goodwin.

At least 19 recordsLinked to original sources
PubMed1985

Cecil Arthur Hoare

Explore the source record for details and available documents.

History, Modern 1601-↗
PubMed1977

Trypanocidal activity of blood and tissue fluid from normal and infected rabbits treated with curative drugs.

A new technique for determining the trypanocidal activity of body fluids has been devised, using very small quantities in the wells of plastic microtest plates. The activities of blood and tissue fluid of rabbits have been measured after the infection of melarsoprol, suramin, diminazene aceturate and isometamidium chloride. Activity against Trypanosoma (Trypanozoon) brucei persisted in body fluids for a shorter time in treated normal rabbits than in treated rabbits infected with the trypanosome. The difference was caused by the participation of the immune response of the infected animals. The new technique was sensitive enough to detect these interactions of chemotherapy and immunology and should be of use in the study of new trypanocidal compounds.

Animals↗