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Biomedical subjects

L G Danielsson

Publications and source records attributed to L G Danielsson.

At least 37 records · Page 2Linked to original sources
PubMed1989

Intracellular ion exchange between cytoplasmic potassium and granule histamine, an integrated link in the histamine release machinery of mast cells.

Rat peritoneal mast cells isolated by gradient centrifugation in Percoll were placed between two membrane filters in a Sartorius filter apparatus and superfused with isotonic balanced salt solutions or with deionized isotonic sucrose. Histamine was released according to ion exchange kinetics. Our explanation of the observed phenomena is as follows. The superfusion induces a flow of cytoplasmic K+ ions across the histamine-containing granules, resulting in an ion exchange K+ in equilibrium Hi+ ions at the histamine binding sites. The concomitant equimolar outflow of histamine and potassium is considered to be due to a functional interplay between two histamine pools, a release and a donor pool. As the result of the K+ in equilibrium Hi+ ion exchange at the histamine binding sites of the release pool, these sites become transiently occupied by K+ ions only to be immediately reoccupied by Hi+ ions from the donor pool. The observed equimolar outflows are consistent with a 1/1 molar ratio in the exchange between histamine and potassium ions. The essential role of cytoplasmic potassium in the histamine release mechanism is a new and important observation with possible implications not only as to histamine release in general (including so-called 'spontaneous' histamine release) but also as to the release of biogenic amines and other positively charged substances stored in granules in ionic linkage to the matrix.

Animals↗
PubMed1989

Winged scapula due to osteochondroma. Report of 3 children.

Three children with winged scapula due to subscapular osteochondromata are reported. One case with multiple osteochondromatosis had two subscapular lesions. After resection, our cases became normal immediately and had no recurrence.

Bone Neoplasms↗
PubMed1987

Transient synovitis of the hip. Its incidence, epidemiology and relation to Perthes' disease.

In a prospective five-year study, 294 episodes of acute transient synovitis of the hip were diagnosed in 275 children. The average annual incidence was 0.2% and the accumulated risk of suffering at least one episode was 3%. The risk of recurrence was 20 times greater than the risk of having a single episode. Perthes' disease was diagnosed from one to five months after the acute attack of synovitis in 10 cases (3.4%). Review of the initial radiographs revealed signs of avascular necrosis in three of the 10 cases, and an increased joint space in five. Only two cases had had completely normal radiographs. The value of routine radiographs taken after three months was minimal. Factors associated with the incidence of Perthes' disease included prolonged time in traction before the range of hip movement became normal, increase in joint space on the initial radiographs and the recurrence of hip symptoms after initial relief.

Child↗
PubMed1986

Elbow fractures in children. An epidemiological analysis of 589 cases.

The radiographs of 589 elbow fractures in children under the age of 16 years were reviewed. The most common fractures were: supracondylar fracture of the humerus -55 per cent, fracture of the radial neck -14 per cent, and fracture of the lateral humeral condyle -12 per cent. One fifth of all fractures of the olecranon were associated with another elbow fracture; most often a fracture of the medial epicondyle. The average annual incidence of elbow fractures in the age group studied was 12 per 10.000 (10.0-14.7) without a significant change of the incidence between 1950 and 1979. Supracondylar and lateral condylar fracture of the humerus and fracture of the olecranon occurred more often in boys. Fractures of the lateral humeral condyle were more often caused by higher energy levels than the other fracture groups.

Accidental Falls↗
PubMed1986

Epicondylar elbow fracture in children. 35-year follow-up of 56 unreduced cases.

Fifty-six conservatively treated children (7-17 years) with a displaced (1-15 mm) fracture of the medial humeral epicondyle were examined 35 (21-48) years after the injury. In 31 cases a pseudarthrosis had developed of which 3 had mild ulnar nerve symptoms. The function and range of motion of the elbow was good in all cases.

Adolescent↗
PubMed1986

Median nerve entrapment in elbow dislocation. A case report.

When the elbow dislocated posteriorly in an 11-year-old boy the median nerve was caught behind the medial epicondyle and in the joint. The condition was diagnosed at 7 months when a total paralysis had developed. Good function was obtained after neurolysis. This rare condition has typical signs and symptoms which should permit an earlier diagnosis.

Child↗
PubMed1986

Late results in 65 physeal ankle fractures.

Fifty-nine Salter-Harris III and IV lesions of the medial malleolus, Tillaux fractures, and triplane fractures were examined after 9 (3-32) years to assess the frequency of late symptoms, deformity, joint incongruity, and secondary arthrosis. Six out of 18 Salter-Harris III and IV lesions of the medial malleolus were reduced open, none of which had any signs of growth disturbance, whereas 1 case, left with a 3-mm residual dislocation, had 5 degrees of anterior angulation. Of the 17 Tillaux fractures, ten were not reduced and two of these gave slight symptoms, whereas five openly reduced fractures were asymptomatic at follow-up. Out of 18 triplane fractures, not reduced, two gave slight ankle pain and another had 6 degrees of anterior angulation, whereas three of ten reduced fractures were symptomatic. The overall results were good and no case of arthrosis, defined as reduction of the joint space, was found in any of the fracture groups despite a follow-up of 12 or more years in one third of the cases.

Adolescent↗
PubMed1986

Resection for macrodactylism of toes. Report of three cases.

Three cases of macrodactylism of toes were operated on with a V-shaped resection: the toe, approximately two thirds of the metatarsals, and part of the adjacent interosseous muscles were resected. The cosmetic and functional results were good.

Child, Preschool↗
PubMed1984

Attitudes to CDH.

Explore the source record for details and available documents.

Hip Dislocation, Congenital↗
PubMed1984

The relation between labor and coxarthrosis.

Three hundred thirty-two laborers in a shipyard, all of whom had been working for decades in heavy industry, were compared with regard to the occurrence of coxarthrosis with a similar sized group of white-collar workers and with a random population sample. All three sets of men were of the same age. About one-fourth (the same in all three groups) had been referred for a hip roentgenographic examination at some time over the previous decades. In the group of laborers and their white-collar controls, coxarthrosis occurred in about 3%, with no difference between the two samples. The occurrence was less, but not significantly less, in those men who had been randomly selected from the population.

Aged↗
PubMed1983

Children's ankle fractures. Classification and epidemiology.

In an investigation of childhood and adolescence fractures (age groups 0-16) occurring in Malmö during 1950, 1955, 1960, 1965, 1970 and 1975-79, a total of 8682 were found. Four per cent or 373 ankle fractures were classified according to their roentgenological appearance. Avulsion fractures of the tip of the lateral malleolus were the most frequent, followed by fractures involving the distal fibular physis. Triplane and Tillaux fractures were the third and fourth most common fracture groups. Tillaux fractures were more common in girls (0.01 greater than P greater than 0.001). There was no statistically significant difference between the sexes in the other fracture groups or in the whole series. Most injuries were caused by low energy trauma. A foot caught in a bicycle wheel resulted more often in an epiphyseal fracture of the lateral malleolus than any other type of fracture. Otherwise no other etiological factor caused a significant number of cases in any fracture group. There was a seasonal variation with twice as many fractures during April and September as compared with July and December. The incidence showed a steady increase during growth which ceased after the early teens due to a lower incidence among girls in the age groups 15-16. The incidence increased significantly during the 30 years covered by this study.

Adolescent↗
PubMed1983

Apophysitis of the olecranon. A report of four cases.

Apophysitis of the olecranon is described in one girl and three boys from 9 to 13 years of age. The symptoms were pain and tenderness and radiography showed fragmentation. The symptoms improved and disappeared with rest.

Adolescent↗
PubMed1981

Traumatic dislocation of the radial head at birth.

A female delivered in a breech presentation after manipulation of the arms was found 2 days later to have sustained anterior dislocation of the left radial head. Surgical correction proved successful, and when re-examined 5 years later the elbow had remained normal. It is probable that in many cases of unilateral displacement of the radial head, detected later in life but reported as congenital, the malposition has been a sequela after unrecognized birth injury.

Birth Injuries↗
PubMed1980

Avulsion fracture of the lateral malleolus in children.

Five girls under the age of 13 years with recurrent symptoms after ankle injuries were found on radiography to have a bony fragment close to the tip of the fibula. At operation it was found that the fragment was attached to the proximal end of the anterior talofibular ligament except in one case in which the fragment had no ligamentous attachment. In the latter case a rupture of the anterior talofibular ligament itself was also found. There was no sign of ankle instability. Removal of the fragments relieved the symptoms in each girl and it is suggested that the symptoms in such cases are due to the bony fragment rather than to ligamentous injury.

Adolescent↗
PubMed1980

Iatrogenic pronator syndrome: case report.

A case of congenital radio-ulnar synostosis with functional disability due to fixation of the forearm in maximal pronation was operated on with a rotational osteotomy in the proximal third of the forearm. Within four days postoperatively a total paralysis of the median nerve gradually developed. The median nerve was therefore explored and found to be strongly compressed by the stretched pronator teres and the superficialis bridge which were sectioned. Full motor and sensory recovery gradually occurred.

Adolescent↗