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L Frazier

Publications and source records attributed to L Frazier.

At least 19 recordsLinked to original sources

The National Violent Death Reporting System: an exciting new tool for public health surveillance.

The US does not have a unified system for surveillance of violent deaths. This report describes the National Violent Death Reporting System (NVDRS), a system for collecting data on all violent deaths (homicides, suicides, accidental firearms deaths, deaths of undetermined intent, and deaths from legal intervention, excluding legal executions) in participating states. The NVDRS centralizes data from many sources, providing a more comprehensive picture of violent deaths than would otherwise be available. The NVDRS collects data on victims, suspects, and circumstances related to the violent deaths. Currently, 17 US states participate in the NVDRS; the intention is for the NVDRS to become a truly national system, representing all 50 states, the District of Columbia, and the US territories. This report describes the history of the NVDRS, provides an overview of how the NVDRS functions, and describes future directions.

Centers for Disease Control and Prevention, U.S.↗

Homicide of children aged 0-4 years, 2003-04: results from the National Violent Death Reporting System.

INTRODUCTION: To better understand, and ultimately prevent, infant/child homicide, it is imperative to more thoroughly elucidate the circumstances and conditions related to such instances. Data were obtained from the US National Violent Death Reporting System (NVDRS) to illuminate circumstances related to homicide among children aged 4 years or less, and to identify demographic groups which may be at increased risk. METHODS: The NVDRS is an active surveillance system that provides comprehensive information on all violent deaths that occur within participating states within the US. Standard statistical tests were conducted to determine homicide rates among children ages 0-4 across states that provided data for both 2003 and 2004 (Alaska, Maryland, Massachusetts, New Jersey, Oregon, South Carolina, and Virginia). These data were further used to investigate infant/child homicides by race, gender, and other relevant circumstances (for example, victim-suspect relationship, weapon type, and location of homicide). A Poisson regression model was fitted to the sample data to investigate the multivariate relationship between the infant/child homicide rate and available demographic information. RESULTS: The 2003 homicide rate for children ages 0-4 was 3.0 per 100,000 population. The 2004 homicide rate was 2.5 per 100,000 population. African Americans were 4.2 times as likely as whites to be victims of homicide. Suspects were commonly parents/caregivers. The vast majority of infant/child homicides occurred in houses or apartments, using weapons that include household objects. CONCLUSION: Homicides of infants and young children are most often committed in the home, by parents/caregivers, using "weapons of opportunity". This suggests that the risk of infant/child homicide is greatest within the primary care giving environment. Moreover, the use of "weapons of opportunity" may be indicative of maladaptive stress responses. Prevention and intervention strategies to reduce infant/child homicide should target the home environment and attend to maladaptive stress responses.

Black or African American↗

Multilocus effects of the renin-angiotensin-aldosterone system genes on blood pressure response to a thiazide diuretic.

BACKGROUND: The renin-angiotensin-aldosterone (RAA) system regulates blood pressure (BP) levels and influences responses to antihypertensive medications. Variation in RAA system genes has been reported to influence interindividual differences in BP levels and the occurrence of hypertension (HTN). METHODS: We evaluated the relationship between variation in genes of the RAA system and interindividual differences in BP response to a thiazide diuretic. Analyses were carried out in a race- and gender-specific manner in 255 unrelated hypertensive African-Americans (125 men and 130 women) and 246 unrelated hypertensive non-Hispanic Whites (133 men and 113 women). RESULTS: The angiotensin II receptor (AT(1)R) A1166C and angiotensinogen G-6A polymorphisms had a significant effect on systolic BP response to the diuretic in African-American women. Multilocus analyses indicated that the effects of these genes combined additively to influence response. Results of a permutation test to adjust for multiple comparisons and the possible nonindependence among genotypes remained significant at the P=0.003 level. CONCLUSIONS: Among African-American women, particular gene variations in the RAA system have additive effects on BP response to a thiazide diuretic.

Adult↗

CDC's National Violent Death Reporting System: background and methodology.

OBJECTIVES: This paper describes a new surveillance system called the National Violent Death Reporting System (NVDRS), initiated by the United States Centers for Disease Control and Prevention. NVDRS's mission is the collection of detailed, timely information on all violent deaths. DESIGN: NVDRS is a population based, active surveillance system designed to obtain a complete census of all resident and occurrent violent deaths. Each state collects information on its own deaths from death certificates, medical examiner/coroner files, law enforcement records, and crime laboratories. Deaths occurring in the same incident are linked. Over 270 data elements can be collected on each incident. SETTING: The 13 state health departments of Alaska, Colorado, Georgia, Maryland, Massachusetts, New Jersey, North Carolina, Oklahoma, Oregon, Rhode Island, South Carolina, Virginia, and Wisconsin. SUBJECTS: Cases consist of violent deaths from suicide, homicide, undetermined intent, legal intervention, and unintentional firearm injury. Information is collected on suspects as well as victims. INTERVENTIONS: None. OUTCOME MEASURES: The quality of surveillance will be measured in terms of its acceptability, accuracy, sensitivity, timeliness, utility, and cost. RESULTS: The system has just been started. There are no results as yet. CONCLUSIONS: NVDRS has achieved enough support to begin data collection efforts in selected states. This system will need to overcome the significant barriers to such a large data collection effort. Its success depends on the use of its data to inform and assess violence prevention efforts. If successful, it will open a new chapter in the use of empirical information to guide public policy around violence in the United States.

Cause of Death↗

Violent attacks on Middle Easterners in the United States during the month following the September 11, 2001 terrorist attacks.

OBJECTIVES: To document and describe hate related violent attacks on Middle Easterners or those perceived to be Middle Easterners during the month following the September 11, 2001 terrorist attacks in New York City and Washington, DC. METHODS: The LexisNexis database of newspaper reports were used to identify incidents of hate related violent acts against Middle Easterners or those perceived to be Middle Easterners in the US between September 1 and October 11, 2001. A total of 100 incidents of hate related violence were identified in the 2659 news articles that were reviewed. RESULTS: Of the 100 incidents of violent victimization that took place during the period September 1 to October 11, only one incident occurred before September 11. The 99 incidents that occurred after September 11 involved at least 128 victims and 171 perpetrators. Most violent victimizations occurred within 10 days of the attacks, involved male perpetrators and male victims, and occurred in convenience stores, on the streets, at gas stations, at schools/colleges, and at places of worship. DISCUSSION: Most violent victimizations occurred in the 10 days immediately following the terrorist attacks indicating that interventions that promote tolerance and understanding of diversity need to be implemented quickly in order to be effective. In addition, patrolling by police and Neighborhood Watch programs around convenience stores and gas stations may also be effective strategies for reducing hate related violent crimes.

Adolescent↗

The feasibility of evaluating a tobacco control intervention for working youth.

OBJECTIVES: To describe the feasibility of implementing evaluation methods for a worksite tobacco control intervention for teens. Indicators of feasibility included employment stability, response rates to multiple surveys, and self reported 30 day smoking. DESIGN: Grocery stores that were part of a single chain were randomised to four intervention stores and five control stores as part of the SMART project, a phase II methods development study designed to reduce smoking among working adolescents. SUBJECTS: Data on smoking in the last 30 days and employment patterns were collected from working teens aged 15-18 years at seven data points over the 12 month intervention period using cross sectional surveys. RESULTS: Data on employment stability indicate that employee turnover rates averaged 21% over the seven administrations. Response rates for the seven surveys ranged from 43-77% and were slightly greater in the control stores than the interventions stores (71% v 59%, p = 0.06). Mean current smoking at the individual store level ranged from 9-32% and there was a negative correlation between smoking prevalence and response rate by survey and by store (-0.029, p = 0.03). Among smokers who completed at least two surveys, there were no significant differences between intervention and control store on changes in the frequency of smoking. CONCLUSIONS: Evaluating a tobacco control intervention in the grocery store setting requires multiple survey assessments to monitor changes in smoking among adolescents. Strategies are needed to maintain high response rates and increase the number of multiple responses from eligible teens.

Adolescent↗

Feasibility of implementing intervention methods in an adolescent worksite tobacco control study.

OBJECTIVE: To present feasibility data on SMART, the first teen worksite behavioural tobacco control intervention. DESIGN: This phase II study was designed to estimate the efficacy and feasibility of a small scale, randomised, controlled intervention. SETTING AND SUBJECTS: This study, addressing youths aged 15-18 years, was implemented in four intervention and five control grocery stores that had an average of 44 eligible teens. INTERVENTIONS: The tobacco use cessation and prevention interventions were based on social influences and peer leader models. Employee break rooms served as centres both for interactive activities including open houses, teen advisory boards, peer leader interviews, games and contests; and non-interactive interventions including bulletin boards and table tents with health messages and home mailings. MAIN PROCESS MEASURES: Project staff collected process data on the extent of implementation of intervention activities, participation rates in activities, and contacts with peer leaders. On the final survey, teens reported on awareness of, participation in, and motivation for participating in project activities. RESULTS: Indicators of feasibility were identified and discussed, including the number of activities implemented, teen participation, management support, cost, and barriers to and facilitators of implementation. During the 12 month intervention, a mean of 24.1 interactive activities and 55.3 non-interactive activities were implemented, and a mean 14.2% participation rate per activity per site was achieved. Eighty four per cent of teens reported being aware of SMART, and 39% reported participating in interactive and 67% in non-interactive activities. CONCLUSIONS: Teen smoking cessation rates in worksite programmes might be improved if they are conducted in companies where there is job stability and if teen programmes are part of worksite-wide tobacco control programmes that include both teens and adults.

Adolescent↗

The pronoun bias effect strikes again: a reply to Pynte and Colonna.

The gender of an initial adjectival phase (AP) influences the analysis of a phrase which is a potential main clause subject in French. Pynte and Colonna (this issue) establish this generalization but analyze it without considering critical aspects of sentence structure, specifically, the fact that the AP has a null pronominal subject. If grammars contain a violable constraint requiring coreference between the pronominal subject of an initial subordinate phrase and the subject of the main clause, then in Pynte and Colonna's study perceivers must choose on-line between an analysis which satisfies the same subject constraint and one which doesn't. From this perspective, it is expected that the subject analysis of the ambiguous phrase predominates. Further, on this view, the preference fits with independent generalizations about language such as the existence of switch-reference languages which obligatorily mark the coreference relation between the initial subordinate subject and the main clause subject. It also fits with already established facts about language processing, such as Cowart and Cairns' (1987) Pronoun Bias Effect.

Humans↗

On bound variable interpretations: the LF-only hypothesis.

Under what conditions do perceivers prefer to assign a bound variable interpretation to a pronominal that is ambiguous between a bound variable and a coreferential interpretation? Several experiments were designed to test the hypothesis that language perceivers prefer a bound variable over a coreferential interpretation of a pronoun because the former only requires consultation of a logical form (LF) representation, while the latter requires access to a discourse representation. The hypothesis was disconfirmed in two respects. First, although bound variable interpretations show a processing advantage over coreferential interpretations in VP ellipsis constructions, the preference for bound variable interpretations is not general--it does not extend to other quantificational contexts. Second, the preference for bound variable interpretations in VP ellipsis constructions is not limited to examples in which the antecedent and the ellipsis site occur in the same sentence. If the bound variable advantage were due to the ready availability of the LF for the current sentence, the advantage should disappear across sentence boundaries. An alternative hypothesis is then considered which could explain the source of the bound variable advantage in VP ellipsis contexts.

Humans↗

Processing coordinate structures.

Coordination often involves syntactically like categories. Based on the results of four reading time studies, it is argued here that the syntactic like-category restriction is not grammatical. Coordination of unlike categories can be just as acceptable as coordination of like categories. However, syntactically like category coordination is processed faster than coordination of unlike categories even when the two sentence types are judged to be fully acceptable. Further, parallelism of conjuncts facilitates processing regardless of whether it is parallelism in the category of the conjuncts (a property which the grammar might regulate) or parallelism in the internal structure of the conjuncts (a property which the grammar does not regulate, on anyone's view). Parallelism did not facilitate processing when the structure of a subject and object were manipulated, implying that parallelism effects are largely limited to the conjuncts of a coordinate structure and not due simply to the repetition of a phrase with a particular shape.

Cognition↗

Factors influencing blood pressure: development of a risk model.

A review of the literature suggests that blood pressure (BP) is multifactorial and is affected by the interactions of genetics, physiology, responses to the environment, and lifestyle factors that have increasing influence as one ages. The effect of these factors on hypertension (HTN) risk as one ages is depicted in the author's Hypertension Risk Model. The model emphasizes HTN risk in the older adult--age 50 and older--and shows the interaction of the factors influencing HTN development and BP assessment methods. Implications of three methods of BP assessment--(1) static BP, (2) 24-hour ambulatory blood pressure monitoring, and (3) clinic blood pressure reactivity (BPR) protocol--are discussed. The model may be useful for understanding factors that contribute to HTN and for guiding BP assessment for clinical researchers. Addressing the factors associated with the sympathetic system activity from various environmental stressors requires assessing dynamic BP, particularly in the older hypertensive adult who has increased BPR. Further research should focus on ambulatory blood pressure studies in older adults that would provide the methods and instrumentation needed to assess HTN and therefore decrease mortality and morbidity in this population.

Blood Pressure Determination↗

Taking on semantic commitments, II: Collective versus distributive readings.

In earlier work, Frazier and Rayner (1990) provided evidence for a processing principle termed the Minimal Semantic Commitment (MSC)hypothesis. In the present study, we used the MSC hypothesis as a starting point in addressing the issue of when to treat mental representations as vague versus determinate and ambiguous. Given ambiguous representations, the MSC hypothesis predicts that the processor will commit to one interpretation (the grammatical ambiguity hypothesis). On the other hand, given a single underspecified representation, the MSC hypothesis predicts that the processor will await disambiguating information before fully committing to an interpretation (the vagueness hypothesis). In an experiment designed to evaluate these hypotheses with respect to the representation of distributivity, participants' eye movements were recorded as they read sentences containing distributive or collective predicates that were either disambiguated by a preceding adverb or left locally ambiguous by delaying the disambiguating adverb until the end of the predicate. The results suggested that a semantic commitment is made in locally indeterminate cases as evidenced by a significant interaction of ambiguity and distributivity in first pass times, total times, and regressions. If the difficulty of distributives simply reflected the difficulty of postulating a distributive operator when evidence warranting it is encountered, then no interaction would be expected. Hence we argue that the distributive/collective distinction is treated as a matter of ambiguity rather than as one of vagueness. In the absence of evidence for a distributive reading, the processor commits itself to a collective reading sometime during the processing of the predicate (before the disambiguation in our late disambiguation examples). The findings are discussed in relation to recent linguistic work on the representation of distributivity.

Humans↗

Construal: overview, motivation, and some new evidence.

Is there underspecification in the syntactic phrase marker constructed during on-line sentence analysis? According to the construal hypothesis (Frazier & Clifton, 1996), a very limited amount and type of structural underspecification is available to the human sentence parsing mechanism. Here we present the basic definitions of construal, illustrating the theory with some already published evidence. We also discuss several new pieces of evidence, from our laboratory and elsewhere, that support the construal hypothesis. We end by raising the question of what kind of mechanism operates in the process of interpreting a nonprimary phrase (a phrase that receives an underspecified syntactic analysis), and conclude that it is not a process of competition between multiple activated possible analyses but instead is a process in which the sheer existence of ambiguity need not result in increased processing cost.

Humans↗

Favor referential representations.

Avrutin and Hickok (1993) argue that agrammatic patients have the ability to represent nonreferential or "government" chains ("who ... e") but not referential or "binding" chains ("which girl ... e"). By contrast, we propose the "referential representation hypothesis," which suggests that agrammatics attempt to cope with their well-known capacity limitations by favoring referential or content-based representations. This predicts that agrammatic patients' performance should degrade noticeably as task demands increase, and referential demands should take priority over computational ones. In a semantic task, referential phrases should lead to better or more accurate performances. In syntactic tasks, the availability of a referential or content-based representation will interfere with the development of a syntactic representation, resulting in worse syntactic performance on the referential phrases than on nonreferential ones. This predicts that agrammatic patients should incorrectly accept (resumptive) pronoun sentences with a referential wh-phrase because the pronouns will find the semantic or discourse referent of the referential wh-phrase and take it as an antecedent for the pronoun. However, they should reject a (resumptive) pronoun in a sentence with the nonreferential question constituent "who" or "what." "Who" and "what" will remain in syntactic form, since they have only grammatical content and therefore will have only a "nonreferential" syntactic representation. Consequently, they cannot serve as the antecedent of the pronoun. These predictions were largely confirmed by the results of a grammaticality judgement study. Agrammatics performed well on questions with pragmatic biases but failed to distinguish reliably between grammatical and ungrammatical questions where pragmatic biases were neutralized. They assigned especially low ratings to object gap sentences with referential wh-constituents, as predicted. They assigned relatively high ratings to ungrammatical subject pronoun sentences with either type of wh- constituent. The agrammatics accepted ungrammatical reflexive sentences even though syntactic number and gender features alone could have been used to correctly judge the sentences. We attribute this, too, to the unavailability of a reliable syntactic representation of those phrases with referential or extragrammatical semantic content.

Adult↗