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Biomedical subjects

L F Ross

Publications and source records attributed to L F Ross.

At least 37 records · Page 2Linked to original sources
PubMed1989

Fermentation of carbohydrates under aerobic and anaerobic conditions by intestinal microflora from infants.

To determine how factors involved in infant carbohydrate metabolism could be effectively assayed in vitro, fecal materials from healthy infants were obtained and tested with fermentation mixtures incorporating glucose, fructose, and lactose incubated under aerobic and anaerobic conditions. The amounts of organic acids, hydrogen, carbon dioxide, and methane produced were determined. Principal component analysis indicated that products of the three sugar systems produced very similar factor patterns and, therefore, all three sugars may not be required to adequately characterize intestinal microbial fermentation processes. Moreover, the fermentation processes under aerobic and anaerobic conditions produced essentially identical cluster patterns of the factors from the three sugar systems. Collectively, the results indicated that two sugar systems, glucose and lactose, measured under aerobic fermentation conditions sufficed in accounting for most of the variation among babies.

Aerobiosis↗
PubMed1987

Simultaneous determination of carbohydrates and products of carbohydrate metabolism in fermentation mixtures by HPLC.

An improved procedure for separating and quantitating carbohydrates, alcohols, and organic acids in fermentation mixtures metabolized by intestinal microflora is described. The high-pressure liquid chromatographic method is efficient, reproducible, and sensitive. A column packed with cation-exchange resin in the hydrogen form, eluted isocratically with 0.028 M H2SO4 at 40 degrees C separates the compounds of interest. The eluate is monitored with ultraviolet and refractive index detectors in series. On-line acquistion and storage of detector output by a computer allows post-analysis data manipulation and quantitation. Using this method, the metabolic profiles for the fermentation of glucose, fructose, lactose, and sucrose by several intestinal microorganisms are characterized and compared.

Carbohydrate Metabolism↗
PubMed1984

Carbon dioxide laser and electrosurgical wound study with an animal model: a comparison of tissue damage and healing patterns in peritoneal tissue.

This study was designed to compare the effect of wound healing after the use of the carbon dioxide laser and the electrosurgical unit on the peritoneal mesothelium of the New Zealand white rabbit. The biophysical parameters were held constant and identical in both groups. The effects were compared in terms of tissue damage, adhesion formation, and healing time. The animals were killed on days 0, 5, 10, 15, 20, and 25. Gross anatomic and histologic findings were recorded. The laser, when compared to the electrosurgical unit in this study, produced no adhesion formation and less tissue injury, immediately and throughout the healing phase (p less than 0.0039).

Animals↗
PubMed1983

Linear and nonlinear effect of the argon laser on a fallopian tube animal model.

Rabbit fallopian tubes were used as models to demonstrate the delayed effects of the argon laser wavelength on tissue. Power density, energy density, and velocity were all variables in the experiment. Three groups of ten rabbits were sacrificed two at a time, on days 0, 5, 10, 15, and 20. The results clearly showed delayed tissue changes associated with fibrosis. Mathematical and theoretical comparisons of the argon laser to the carbon dioxide laser help express the advantages and disadvantages of the use of the argon laser in fallopian tube surgery. The return of organ function with respect to time has possible significance to studies of human fallopian tube surgeries.

Animals↗
PubMed1983

Comparative gross and histological study of the effects of scalpel, electric knife, and carbon dioxide laser on skin and uterine incisions in dogs.

This study concerns the gross histological effects of scalpel, electric knife, and carbon dioxide laser incisions on skin and uterine tissue in dogs. Tissue studies comparing the carbon dioxide laser with the scalpel and electric knife have frequented the literature. However, a gross and histological comparison specifically involving uterine tissue is not presently known to have been reported. The evaluation on this series of animals considers both the skin and the uterus in an abdominal approach to evaluate the carbon dioxide laser for potential intrauterine surgery. Tissue sampling of both skin and uterus at 2, 6, and 8 weeks postoperatively were histologically examined to evaluate healing rates and degree of scar formation.

Animals↗
PubMed1983

Carbon dioxide laser treatment of vaginal adenosis in DES-exposed offspring: a prospective study.

Seventy-nine patients with history and physical findings characteristic of antenatal DES exposure were randomly divided into two groups. Fourty-four DES-exposed offspring had their vaginal adenosis treated with the carbon dioxide laser (group I), and the remaining 35 DES-exposed offspring (group II) did not receive any specific treatment for this condition. Additionally, the 79 DES-exposed offspring were compared to an age-matched control population (group III). Treatment of vaginal adenosis with the carbon dioxide laser did not significantly reduce the incidence of development of new dysplasia in the DES-exposed offspring. This study also showed no statistical difference (p less than or equal to 0.05) in the incidence of dysplasia in DES-exposed offspring as compared to a control population.

Adenocarcinoma↗
PubMed1983

Colposcopy and the CO2 laser for treatment of cervical intraepithelial neoplasia. An analysis of seven years' experience.

We performed a study to determine the efficacy of laser therapy for the three grades of cervical intraepithelial neoplasia. Two hundred ninety-two patients were studied. Over 90% of the cases occurred in women between 20 and 30 years of age. Among the 21 patients (7%) with persistent disease, 12 (86%) of the cases were diagnosed within the first six months after laser treatment. Those patients were retreated. The overall cure rate in the study population was 96%.

Adult↗