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Biomedical subjects

L E Phillips

Publications and source records attributed to L E Phillips.

39 records · Page 3Linked to original sources
PubMedDate not supplied

Hepatitis due to herpes simplex virus in a nonpregnant patient: treatment with acyclovir.

A previously healthy 19-year-old nonpregnant woman had disseminated infection with herpes simplex virus. The disseminated disease was accompanied by hepatitis. The patient was treated with parenteral acyclovir (5 mg/kg) given every 8 hr. The patient's symptoms resolved after three days of therapy. A review of five similar cases that were observed in healthy nonpregnant and nonimmunosuppressed individuals showed that all five patients died. Thus, rapid diagnosis of this potentially fatal condition is important, and the possible use of acyclovir for such cases should be considered.

Acyclovir↗
PubMedDate not supplied

Correlation of ultrasonography and bacteriology of the endocervix and posterior cul-de-sac of patients with severe pelvic inflammatory disease.

We evaluated 30 patients admitted with a diagnosis of pelvic inflammatory disease (PID) by culdocentesis and ultrasonography to determine the severity of disease in relation to endocervical and culdocentesis bacteriology. Specimens from the endocervix were cultured for Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma hominis, and Ureaplasma urealyticum. In addition, culdocentesis fluid was cultured for aerobes and anaerobes. Patients with N. gonorrhoeae or C. trachomatis had significantly milder disease (P less than 0.05) compared with patients whose specimens were negative for those organisms. Furthermore, those patients with ultrasound confirmation of a tubo-ovarian complex had significantly (P less than 0.0001) greater recovery of aerobes and anaerobes from culdocentesis fluid than did patients with milder disease.

Adult↗