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Biomedical subjects

L E Hendrix

Publications and source records attributed to L E Hendrix.

28 records · Page 2Linked to original sources
PubMed1979

Abnormal factor VIII in chronic renal failure.

Factor VIII procoagulant activity (VIII-C), related antigen (VIII-AG), and von Willebrand factor (VIII-vWf) were measured in 38 patients with chronic renal failure (CRF), in 19 patients with normal renal function from a general medical ward, and in 17 normal subjects. Wide variation in the levels of factor VIII (FVIII) functions were found in the group of CRF patients. There was no correlation between the levels of the three individual activities of FVIII in renal disease. The levels of the three functions were elevated in the patient controls and no significant differences were found between the two groups of patients, although both groups were significantly different from the normal subjects. Increased electrophoretic mobility (EM) was detected in 22 of the 38 patients with CRF (58%) compared to seven of the 19 patients controls (37%). These studies suggest caution in interpretation of changes in FVIII status in patients with other clinical disorders, such as liver disease.

Antigens↗
PubMedDate not supplied

Surface coil MR evaluation of a lacrimal gland carcinoma.

Recognition of both bone involvement and extraorbital spread of tumor is essential for the correct diagnosis and treatment of lacrimal fossa masses. We present a case of adenoid cystic carcinoma of the lacrimal gland where bone invasion and extraorbital extension were better defined with magnetic resonance imaging than with CT.

Carcinoma, Adenoid Cystic↗
PubMedDate not supplied

High-intensity signals within the posterior pituitary fossa: a study with fat-suppression MR techniques.

Five different theories have been proposed to explain the high-intensity signals within the posterior pituitary fossa seen on MR: (1) a paramagnetic effect of phospholipids in the posterior lobe, (2) lipid in pituicytes in the posterior lobe of the pituitary, (3) neurosecretory granules in the posterior lobe, (4) fat within the sella but outside the pituitary gland, and (5) fat in bone marrow in the dorsum sellae. Previous reports have contained conflicting evidence on which of these structures is the cause of the high-intensity signals within the posterior sella. The purpose of this study was to examine the high-intensity signals of the normal posterior sella with fat-suppression MR techniques to reevaluate the contribution of fat to those signals. The sellae of 19 normal volunteers and two cadavers were imaged with MR with a commercially available unit and a research fat- water-suppression technique. High-intensity signals in the posterior sella were observed in all 21 subjects on conventional T1-weighted MR images. In two volunteers, the high-intensity signals in the posterior sella were suppressed with fat-suppression techniques; in 17 subjects the signals were suppressed with water-suppression techniques. In two volunteers the results were indeterminate. The high-intensity signals in the posterior sella do not behave like lipid in the majority of cases. Our study supports the conclusion that high-intensity signals in the posterior sella may have more than one source. It appears that most of these sources do not suppress with fat-suppression techniques.

Humans↗
PubMedDate not supplied

MR imaging of optic nerve lesions: value of gadopentetate dimeglumine and fat-suppression technique.

Eleven patients with known or suspected optic nerve lesions and eight normal subjects were examined with spin-echo technique at 1.5 T with unenhanced T1-weighted imaging, IV gadopentetate-dimeglumine-enhanced T1-weighted imaging, and enhanced T1-weighted imaging with fat suppression. Two pathologically proved and four presumed optic nerve meningiomas demonstrated significant enhancement and were best seen with the fat-suppression technique. None of the three presumed optic nerve gliomas nor the optic nerves of normal subjects demonstrated qualitative enhancement. We conclude that the use of a fat-suppression technique with gadopentetate dimeglumine enhancement improves delineation of enhancing optic nerve lesions. This technique should be useful for evaluating other anatomic regions where enhancing tissue marginates fat.

Adult↗
PubMedDate not supplied

"Truncation" artifact in MR images of the internal auditory canal.

Dry skulls and a phantom were studied to determine whether an intracanalicular dark band in MR images of some acoustic neuromas could be artifactual. A "truncation" artifact was detected in the internal auditory canals of the dry skulls and in a simulated internal auditory canal of the phantom when the width of the canal approximately equaled 4 X (field of view) /N, where N equals 128 or 256, depending on the number of gradient steps chosen. The "truncation" artifact should not be confused with CSF between normal nerves when a canal contains tumor.

Humans↗
PubMedDate not supplied

Gradient recalled echo MR imaging of the jugular foramen.

Axial T1-weighted spin-echo MR images have not proved to be effective in identifying normal structures in the jugular foramen. By correlating cryomicrotomic sections and axial T1-weighted gradient recalled echo images, we identified the neural and vascular contents of the jugular foramen. Further work with gradient recalled echo images is needed to determine the signal characteristics of jugular foraminal lesions.

Glomus Jugulare Tumor↗
PubMedDate not supplied

Magnetic susceptibility artifacts in gradient-recalled echo MR imaging.

Artifacts related to magnetic susceptibility differences between bone and soft tissue are prevalent on gradient-recalled echo images, particularly when long echo delay times are used. These susceptibility artifacts spatially distort and artifactually enlarge bone contours. This can alter the apparent shape of the spinal canal and exaggerate the degree of spinal stenosis seen in patients with cervical spondylosis. The effects of magnetic susceptibility artifacts in gradient echo imaging were studied in a phantom model and the results were correlated with MR images obtained in patients with cervical spondylosis.

Cervical Vertebrae↗
PubMedDate not supplied

Limbic connections.

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Brain Mapping↗