Plasma levodopa and the "on-off" effect.
Explore the source record for details and available documents.
Aged↗
Biomedical subjects
L E Claveria
Publications and source records attributed to L E Claveria.
Pimozide in tardive dyskinesia.
Explore the source record for details and available documents.
Clinical Trials as Topic↗
"On-off" phenomena related to high plasma levodopa.
The neurological deficit and plasma concentrations of levodopa have been studied in a Parkinsonian patient experiencing "on-off" phenomena. Blind evaluations of transient attacks of dysphonia revealed an association between episodes of neurological deterioration and exceptionally high plasma concentrations of levodopa shortly after ingestion. These results indicate that "on-off" phenomena can be toxic reactions to levodopa rather than deteriorations due to inadequate intake or absorption of the drug. Management of patients subject to such attacks should be aimed at minimizing fluctuations in the serum level of the drug.
Aged↗
Radioisotope scanning of the nervous system. Reasons for scanning.
Explore the source record for details and available documents.
Attitude of Health Personnel↗
Glucose tolerance and plasma insulin levels in subarachnoid haemorrhage.
Explore the source record for details and available documents.
17-Hydroxycorticosteroids↗
Ipsilateral symptomatology in left temporal lobe lesions.
Two cases of ipsilateral symptomatology related to left temporal lobe lesions are presented. The possibility of ipsilateral symptoms after temporal lobe lesions has to be considered, mainly when they occur in the dominant hemisphere. Direct or indirect damage to the insula of Reil's sensory-motor secondary area seems to be the motive of these ipsilateral symptoms.
Adult↗