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Biomedical subjects

L Demling

Publications and source records attributed to L Demling.

At least 55 records · Page 3Linked to original sources

A cuffed tube for the treatment of oesophago-bronchial fistulae.

An oesophageal tube provided with a foam-rubber cuff is described. The outside diameter of the cuff can be diminished while the tube is being introduced. After implantation, the expanded foam-rubber cuff achieves additional sealing of the oesophago-bronchial fistula. The tube described is suitable for sealing off oesophago-bronchial fistulae in the absence of the tumour-induced stenosis of the oesophagus.

Carcinoma, Squamous Cell↗

Is the adenoma-carcinoma sequence contradicted by the differing location of colorectal adenomas and carcinomas?

This article takes a look at the different localisation of colorectal adenomas and carcinomas. The risk of malignancy of 4,257 adenomas found in 1742 patients was determined, and the lesions grouped in accordance with various criteria and risk classes. It was found that the distribution of adenoma locations approximated all the more closely to the distribution pattern of carcinoma sites, the higher the malignancy risk of an adenoma group was. The statistical approximation of adenoma and carcinoma localisations as a function of increasing risk of malignancy must be considered an argument in support of the adenoma--carcinoma sequence.

Adenoma↗

Laser lithotripsy of gallstone by means of a pulsed neodymium-YAG laser--in vitro and animal experiments.

Using a flashlamp pulsed Nd: YAG laser it is possible to destroy gallstones within a few seconds (median: 4 sec for stones less than 1.5 cc; 9.5 sec greater than 1.5 cc). In in vitro and animal studies it was shown that the median energy needed for stone destruction varies between 32 Joule for stones less than 1.5 cc and 80 Joules for stones greater than 1.5 cc. A 0.2 mm thick, flexible glass fibre makes possible retrograde laser lithotripsy by conventional endoscopes. Using a suitable technique the danger of thermal damage to tissue is small.

Animals↗

Laser-induced shockwave lithotripsy of gallstones.

With the aid of a Q-switched Nd:YAG laser with energy transmission via a flexible glass fiber, it proves possible under laboratory conditions, to destroy gallstones reliably and reproducibly. Lithotripsy is effected mechanically via a laser-induced local shockwave.

Cholelithiasis↗

Hemostasis--therapeutic alternatives to the laser.

In clinical practice, there are a number of other endoscopic procedures for attaining hemostasis available as alternatives to laser hemostasis. Of these the following may be emphasized: Modified electrocoagulation procedures such as EHT coagulation, bipolar or multipolar coagulation, and sclerotherapy. The efficacy of these "laser-alternative" methods of hemostasis has already been demonstrated in clinical studies, and is unquestioned. Large comparative investigations that would provide definitive information on the relative effectiveness of the various techniques, have yet to be carried out. If, however, we consider such aspects as practicability and economy, the laser would appear to be a "dinosaur" among the endoscopic procedures presently available for hemostasis. The oldest recognized fiber-endoscopic instrument for hemostasis, it is anything but highly mobile, and is bound to a fixed location. In addition, it is as expensive as a museum exhibit. If the only indication for its use were hemostasis, it would probably have vanished from the scene.

Electrocoagulation↗

Palliative laser treatment of malignant stenoses in the upper gastrointestinal tract.

The present state of palliative laser therapy of inoperable malignant tumor stenoses in the upper gastrointestinal tract is reviewed. Indications, contraindications, several different sources of energy and forms of energy application, as also the various technical procedures, are discussed. Finally, the authors' experience with palliative laser therapy in 62 patients, and the results of an international inquiry covering data obtained in 1,359 patients, are presented.

Endoscopy↗