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Biomedical subjects

L Damianov

Publications and source records attributed to L Damianov.

33 records · Page 2Linked to original sources

[Tocolytic substituent treatment with Magnerot in threatened abortions and premature labor from the 16th to the 36th gestational week].

The Mg's low level in the sera and the urine correlate with clinical symptoms of uterine contraction in pregnant women from the 16th-36th gestation week. The authors present their experience with the use of removal tocolytic curing with Magnerot tabl. in the cases of 60 pregnant women with uterine pain and contractions from 16th to 36th gestation week and Pelvic Score after Bishop under 4. The effect of the curing is remarkable till from the beginning in the first 4-7 days of it, which is demonstrated with disappearing of the objective and subjective contractions (overviewed in obstetric monitor) and there is normalising of the paraclinical levels of the Mg in the sera and the urine, with normal pregnancy and birth of a healthy and alive child.

Abortion, Threatened↗

[Clinical study of a low-dose contraceptive--Femodene].

The authors present their clinical experience with a low-dose monophasic contraceptive consisting of 30 mcg ethinylestradiol and 75 mcg a gestagen--gestodene (Femoden, Schering). 112 menstrual cycles of 22 women in fertile age were followed. The results show 100% contraception, a good control of the menstrual cycle and tolerance of the preparation.

Adult↗

[A clinical trial with the monophasic contraceptive Marvelon].

The authors present their clinical experience with a monophasic preparation consisting of 30 mcg ethynyl estradiol and 150 mcg desogestrel (Marvelon, Organon). 121 cycles of 24 fertile women were followed. The results show a full contraceptive success, a stable cycle control as well as a low incidence of the side effects.

Adolescent↗

[Pre-eclampsia--the delivery and outcome for newborn infants].

In the present research 50 patients have been examined having average and heavy form of preeclampsia who have entered and have been treated at the university hospital. The percentage of the Caesarean sections for the heavy forms is 72% while for the average forms it is 63%. The impression is that the heavier the preeclampsia is the more often operative delivery is practiced. On the other hand the heavier the preeclampsia is the quicker the delivery completes: approximately 50% of the heavy forms end with operative delivery up to the 32 gestational weeks while for the average forms the percentage is 6.6%. The birth information is compared to the values of Apgar score on the 1st and 5th minutes for the newborn and their outcome in the neonatal period. The general conclusion which is done concerns the optimal gestational time limit for birth in these cases in order to successful outcome for the newborn.

Adolescent↗

[Modern antimycotic therapy in obstetrics].

The research includes 40 pregnant women in the second half of pregnancy with proved microbiological colpitis mycotica. Local treatment was applied with antimycotic Gyno-Pevaril. The following results had been achieved: 82% totally cured during the first course of treatment, 15%--after the second course and 3% (1 patient) needed to be treated a third course of a mixed microbiological flora. The clinical contents, pharmacokinetics and the local way of application secure the harmlessness of the treatment of the colpitis mycotica in pregnant women.

Adult↗

[Delivery in women with heart diseases].

Pregnancy, child-bearing and puerperium raise different problems in front of obstetricians and gynecologist in regard to the type and gravidity of concomitant cardiac defects. During the time period of 1985-1989 the number of child-bearing women with cardiac diseases has increased about 7 times where 76.3% of them aged from 21 to 30 years. With acquired valvular defects were 152 of them (62.2%) with congenital defects were 58 (23.5%) and with vascular diseases--34 (13.9%). A normal birth rate was 41.1% and a caesarean birth--44.1%. Conclusions are drawn and advice are offered considering methods of delivery and behavior throughout pregnancy and puerperium.

Adolescent↗

[Immunoglobulins in the serum of puerperae].

Immunoglobulins G, A and M were determined in sera of parturients up to the sixth day after delivery. The study was carried out on 20 parturients, 17 of whom had normal pregnancy and parturition, 2 of whom underwent preterm delivery and one parturient suffered from pre-eclampsia. Immunoglobulins were determined from the first to the sixth day after delivery. The method of determination was immunodiffusion with Tripartagen Behring Institute. The authors established higher level of immunoglobulin G on the sixth day after delivery than immediately after delivery. There were no significant differences in the established ranges of immunoglobulin A. Immunoglobulin M showed higher values in the parturient with pre-eclampsia during pregnancy and this fact deserves further study.

Female↗

[The treatment of pulmonary thromboembolism in puerperae with pelvic thrombophlebitis].

The possibilities of current conservative treatment were studied on parturients with pelvic thrombophlebitis and lung thromboembolism. It was established that performance of total hysterectomy or usage of vena cava filter in parturients with pelvic thrombophlebitis and lung thromboembolism should be made after careful evaluation and after trials of current conservative treatment (venous application of antibiotics from the sixth generation, metronidazol preparations and heparin).

Anti-Bacterial Agents↗

[Alpha-fetoprotein in the serum of puerperae].

Alpha-fetoprotein was determined in the sera of parturients with normal pregnancy and delivery, parturients with preterm delivery and with preeclampsia. Alpha-fetoprotein was determined by the plates of Behring Institute. The authors established that after delivery alpha-fetoprotein did not differ substantially in the separate groups. Furthermore till the eight day after delivery the reduction of alpha-fetoprotein was minimal with the exception in the parturients with preterm delivery.

Female↗

[Our experience in using nolitsin in puerperal infections (preliminary report)].

The therapeutic possibilities of the chemotherapeutic preparation Nolicine were studied. Clinical and laboratory parameters were followed in dynamics as well as microbiological examination of lochial and wounded secretion in dynamics. The results from the study showed that the applied preparation, when its usage is contemplated with the isolated bacterial flora, is suitable for treatment of some postpartal infections especially in women, who are allergic to antibiotics.

Adult↗