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Biomedical subjects

L D Smith

Publications and source records attributed to L D Smith.

At least 145 records · Page 8Linked to original sources

Chemotherapy of an experimental Fusobacterium (Sphaerophorus) necrophorum infection in mice.

An experimental animal model for testing antibiotics in vivo against Fusobacterium (Sphaerophorus) necrophorum has been developed. It incorporates the subcutaneous injection of the bacteria into mice followed by intraperitoneal administration of the antibiotic at 24, 48, 72, and 96 h. Mean effective dose values are based on the number of survivors 21 days after challenge. Tetracycline was the most effective drug tested, with a mean effective dose of 5.0 mg/kg, compared with mean effective dose values of 11.1 for clindamycin, 11.8 for penicillin-G, and 52.9 for lincomycin.

Animals↗

Clostridium barkeri sp. n.

Clostridium barkeri sp. n. has been described, and its relationship to other clostridia is discussed.

Acetates↗