Computed tomography and the quality of radiation therapy.
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Costs and Cost Analysis↗
Biomedical subjects
L D Simpson
Publications and source records attributed to L D Simpson.
The Proimos device: a gravity oriented blocking system for use in external radiation therapy.
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Abdominal Neoplasms↗
E.s.r. studies of halogenated pyrimidines in gamma-irradiated alkaline glasses.
The reactions of mobile electrons (em-) and oxygen radical anions (O--) with halogenated bases and nucleosides have been studies in gamma-irradiated alkaline glasses by e.s.r. and specific halogen-ion electrode techniques. It is shown that electrons react with halogenated uracil bases (XUr where X = Cl, Br. I but not F) by dissociative electron attachment to form uracil-5-yl radicals (U-) and halogen anions. The relative rates of reaction of em- with XUr decrease in the sequence BrUr greater than ClUr greater than FUr greater than IUr. Thermal annealing studies carried out on U- in H2O and D2O matrices support the hypothesis that U- in H2O hydrates across the 5-6 double bond in the temperature region 135 degrees-155 degrees K, and deuterates to a much smaller extent in D2O at temperatures above 155 degrees K. Studies on bromouridine and bromodeoxyurinde suggest that em- reacts with the base moieties to form U- type radicals which abstract H- from the sugar moieties of adjacent nucleosides.
Bromouracil↗
Radiation therapy of choroid metastasis from breast cancer.
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Breast Neoplasms↗
Computed tomography in radiation therapy (report of the Committee on Radiation Oncology Studies Subcommittee on CT Scanning and Radiation Therapy).
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Drug Therapy↗
Computer-compatible patient contour plotter.
The use of a compact, mobile, relatively inexpensive electromechanical patient-contouring mechanism is described. The system utilizes a Numonics Model 224 graphics digitizer suspended over the patient. The digital X and Y coordinates of the patient contour in either of multiple, parallel transverse, or sagittal planes are inherently accurate to within +/-0.25 mm over a total reading are of 60X90 cm. Display features include the interface to an analog 11-in.X17-in. X-Y plotter with a variable scale-down factor for those contours which would otherwise be larger than the plotting surface. The system is easy to use and may also be readily interfaced for on-line entry of patient contours to calculator- or minicomputer-based treatment-planning systems.
Computers↗