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Biomedical subjects

L D Bores

Publications and source records attributed to L D Bores.

10 recordsLinked to original sources
PubMed1996

Hydrogel intracorneal lenses in aphakic eyes.

BACKGROUND: The theoretical benefits of synthetic keratophakia over conventional corneal lamellar procedures are the elimination of donor concerns and superior refractive predictability. Additionally, synthetic material can be inspected for optical quality and power, and it can be sterilized. Furthermore, visual recovery should be more rapid since epithelium is not removed from the central part of the cornea and the need for keratocyte repopulation is eliminated. OBJECTIVE: To present results on patients who received an intracorneal implant (Kerato-Gel, Allergan Medical Optics, Irvine, Calif) that was made from lidofilcon A, a glucose-permeable hydrogel with an equilibrium water content of 68%. METHODS: The intracorneal implants were implanted in 35 adult patients for correction of aphakia. Inclusion criteria excluded patients with aphakia who were candidates for intraocular lenses. RESULTS: A total of 19 patients were followed up through 2 years postoperatively. For 16 patients with 2-year postoperative refractive data, the average spherical equivalent was -0.63 +/- 2.07 diopters (D). At 2 years, 88% of patients were within +/- 3.00 D of plano and 50% were within +/- 1.00 D. the mean change in Snellen's line for corrected visual acuity was -3.25 lines at 2 years for all patients and -2.0 lines for a subgroup of five patients who were free of vision-limiting preoperative disease. CONCLUSIONS: Results suggest that this intracorneal implant is well tolerated by the cornea and can provide predictable refractive results in patients with high-risk aphakia. Limitations of the procedure are uneven microkeratome resections, loss of best-corrected visual acuity, and irregular astigmatism in some patients. Although these data show good evidence of biocompatibility of the implant material, technical surgical progress is needed to advance this procedure into clinical therapeutic practice.

Adult↗
PubMed1994

Refractive surgery.

Myopia (nearsightedness) and hyperopia (farsightedness) are almost equally distributed in the general population but myopia has received the most surgical attention, probably because it produces the greater disability. It also seems more amenable to surgical correction as the widespread successful employment of radial keratotomy bares out. On the other hand, attempts at surgically correcting hyperopia such as hexagonal keratotomy; thermokeratoplasty; hyperopic lamellar keratotomy, and keratophakia have had a less happy experience. Even the more sophisticated technique of laser photoablation is unable to successfully manage hyperopia. It would seem that steepening the cornea is much more difficult than flattening it. Refractive eye surgery is a new subspecialty of ophthalmology only recently come into its own. Considering the tremendous changes in cataract surgery in the past 30 years it is likely that hyperopia will eventually fall to the refractive eye surgeon.

Corneal Transplantation↗
PubMed1981

A clinical investigation of the surgical correction of myopia by the method of Fyodorov.

The surgical correction of myopia using the method of Fyodorov known as radial keratotomy consists of 16 partial thickness, radial incisions in the cornea, which result in central flattening and peripheral bulging, reducing the degree of myopia. The purpose of this investigation was to determine: (1) the amount of myopia correctable; (2) the time required for stabilization of corneal curvature changes; (3) the degree to which the variables affect the results; (4) the surgical and postoperative complications; and (5) patient motivation and satisfaction. Preliminary results revealed a significant reduction of the myopia. The keratometry readings and refractive correction required appeared to stabilize by the third month. Fluctuating vision and increased glare were the most frequent complications encountered. The preliminary results of 20 cases followed for six months postradial keratotomy are reported.

Adolescent↗
PubMed1981

Radial keratotomy: an analysis of the American experience.

A total of 223 patients with bilateral nonprogressive myopia ranging from - to - 11 D underwent partial-thickness radial keratotomy (400 eyes). Topical anesthesia was used for all surgery and all patients had 16 radial incisions from a preset central optical zone, determined by table and/or formula. Neither corneal diameter or scleral rigidity was taken into account in these groups. Substantial reduction of myopia resulted immediately in all cases, with Group 1 showing a 44% regression of the myopia with stabilization occurring at three months. Group 2 showed a 14% regression of effect. In Group 1, 28% attained an unaided visual acuity (postoperatively) of 20/40 or better for most of the day, while 61% of Group 2 attained the same result. Night glare was present in both groups, usually subsiding in three months. Fluctuation was reported in both groups. Side effects were mild. The comparison of the two groups shows that incisions carried almost to Descemet's membrane and deepened in the periphery resulted in much greater reduction of the myopia and a more permanent and stable effect following surgery. New methods of measuring corneal curvature are necessary and a more satisfactory blade needs to be developed for surgery. Corneal thickness measurements have been made more accurate by the development of the ultrasonic pachymeter.

Adolescent↗