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Biomedical subjects

L Corydon

Publications and source records attributed to L Corydon.

51 records · Page 3Linked to original sources

Corneal ulcer after exposure to vapours from bone cement (methyl methacrylate and hydroquinone).

An operation nurse repeatedly developed a corneal ulcer while mixing bone cement. It is suggested that the ulcer developed because of a composite effect of vapours from bone cement (methyl methacrylate monomer and hydroquinone), in spite of the fact that the Occupational Health Guidelines and the national threshold limit values for chemical substances had been respected. In-vitro and in-vivo animal studies are reviewed.

Adult↗

Corneal astigmatism after cataract extraction. A comparison of corneal and corneoscleral incisions.

Corneal astigmatism after cataract surgery by way of corneal incision (C, n = 62) and corneo-scleral incision (CS, n = 61) was followed for six months. Corneal incisions were closed by continuous nylon 10--0 (7--25 loops, median 14). Corneo-scleral incisions were sutured with single knots (2--10, median value 5). Keratometric results in the C and CS groups are compared. Concerning the degree of astigmatism, pre-operative median values were 0.5 and 0.7 D, respectively. After one week they were 4.5 and 3.0 D; after two weeks 3.3 and 3.0 D; after four months 3.0 and 2.0 D; after six months (final status) 1.5 and 1.7 D, respectively. The differences between C and CS were not significant. For both, astigmatism after cataract surgery did not quite return to pre-operative levels. Concerning the axis (weaker meridian) of corneal astigmatism, the C cases retained their pre-operative distribution, while the CS cases showed the classical shift towards against-rule astigmatism. Final corrected visual acuity was of the same order in the C and CS group. Due to frequent shifts, also of the axis, it is recommended by early (preliminary) glass prescription not to correct the astigmatism, but to give only the best spherical correction.

Adult↗

Progress in cataract surgery using microsurgical technique.

A microsurgical technique for cataract extraction is presented. The operations were performed with a corneal incision and a continuous nylon 10-0 suture. This technique is evaluated by the study of 1289 cases, consecutively operated on. The complication rate was very low. Haemorrhage in the anterior chamber was found in 1%. Delayed reformation of the anterior chamber occurred in only two cases. No cases of iris prolapse occurred. The intraocular pressure was not interferred with by the operation. Wound rupture following removal of the suture three months post-operatively occurred in 1%. The advantages of the corneal incision and continuous nylon suture are discussed (less irritation, good and secure wound closure).

Cataract Extraction↗

A double-blind study of the influence of tranexamic acid on the central corneal thickness after cataract extraction.

A double-blind study of the influence of systemic tranexamic acid on the central corneal thickness after cataract extraction was performed in 17 pairs of patients. Apart from the cataract, no were present. A sequential statistics was used to show that the increase in central corneal thickness after operation was significantly less in the tranexamic acid treated group than in the placebo group. There was no significant difference in intraocular pressure between the tranexamic acid and the placebo treated group. The possible influence of tranexamic acid on the thickness controlling mechanism of the cornea is discussed, and studies concerning the fibrinolytic system, the complement system and the aqueous humour amino acid treated patients are mentioned.

Aged↗

Diathermic capsulotomy versus capsulorhexis: a biomechanical study.

PURPOSE: To compare the mechanical quality of a capsulotomy opening performed by diathermy with that made by capsulorhexis (tearing). SETTING: Department of Ophthalmology, Vejle Hospital, Denmark. METHODS: This study included 12 pairs of human cadaver eyes and 20 pairs of pig eyes. One in each pair was randomly selected for one capsulotomy technique. The capsulotomy edge was stretched in a materials testing machine until break; force and elongation values were continuously recorded. RESULTS: In humans, the extensibility of the diathermic capsulotomy edge was approximately half that of the capsulorhexis edge (mean 38% +/- 4 [SD] versus 68% +/- 6), and the force required to break the edge was reduced by a factor of five (26 +/- 8 mN versus 134 +/- 36 mN). CONCLUSION: The mechanical quality of the diathermic capsulotomy edge is significantly less than that of the capsulorhexis edge, which indicates that the diathermic capsulotomy edge would withstand less surgical manipulation.

Aged↗