Biomedical subjects
L Collie
Publications and source records attributed to L Collie.
Providing information to parents of extremely premature newborns.
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Informed consent in neonatal randomised trials.
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Promoting breastfeeding in the neonatal intensive care unit.
The technology and separation of the mother and baby in the neonatal unit make bonding difficult and create barriers to breastfeeding. This pilot study aimed to define those nursing interventions that promote breastfeeding. The neonatal nurse plays a vital role in the influence of the breastfeeding outcome. Forty-one preterm babies had their breastfeeding activities, (including kangaroo care), recorded daily. The specific phases in preterm infants of 32 weeks or more were identified as 1. stabilisation and assessing ability, 2. controlled challenge, 3. progression and regression and 4. stability of feeding activity. This study has increased the awareness among the neonatal nurses involved as to the nursing practices that promote breastfeeding and has provided a basis from which nurses can promote breastfeeding to mothers of preterm babies.
Haemodynamic effects of intravenous human calcitonin-gene-related peptide in man.
1. The effects of intravenous bolus doses of human calcitonin-gene-related peptide (hCGRP) were studied in ten healthy male volunteers. 2.5, 10 and 25 micrograms of hCGRP and placebo were administered to each subject in a randomized double-blind study. 2. hCGRP had no effect on systolic or diastolic blood pressure in the supine or standing position. 3. hCGRP increased supine and standing heart rate. Both the extent and duration of the tachycardia were dose related. 4. Plasma noradrenaline levels were transiently increased after 10 and 25 micrograms of hCGRP. 5. All subjects displayed marked facial flushing after the two higher doses of hCGRP. 6. We conclude that systemic administration of hCGRP produces tachycardia and stimulation of the sympathetic nervous system in the absence of any change in blood pressure.