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Biomedical subjects

L Collet

Publications and source records attributed to L Collet.

178 records · Page 10Linked to original sources
PubMedDate not supplied

Psychopathological profile of tinnitus sufferers: evidence concerning the relationship between tinnitus features and impact on life.

This study involving 281 French tinnitus sufferers sought to investigate possible correlations between psychopathological profile and scores obtained from three tinnitus questionnaires. The patients all completed a French version of the Mini-Mult--a shortened Minnesota Multiphasic Personality Inventory--and French translations of three questionnaires designed especially for the clinical assessment of tinnitus: Tinnitus Reaction Questionnaire (TRQ), Subjective Tinnitus Severity Scale (STSS) and Tinnitus Handicap Questionnaire (THQ). Significant correlations were found (p < 0.0001) between scores on various Mini-Mult scales and total or factor 1 THQ and total TRQ scores. No significant correlation was found between the STSS and any Mini-Mult score.

Adaptation, Psychological↗
PubMedDate not supplied

Psychometric normalization of a hyperacusis questionnaire.

Clinical hyperacusis consists of a marked intolerance to ordinary environmental sounds, while hearing thresholds are quite often normal. Hyperacusis appears to be a subjective phenomenon, which is not easily defined or quantified by objective measurements. In order to create a tool suitable to quantify and evaluate various hyperacusis symptoms, a questionnaire screening several aspects of auditory symptomatology has been constructed. Two hundred and one subjects (who were either hyperacusic or not), randomly selected from the general population, were tested. A principal component analysis performed on the correlation matrix of the 14 items of the questionnaire isolated three dimensions: attentional, social, and emotional. The three dimensions had satisfactory internal consistency reliability. The mean +/- SD total score was 15 +/- 6.7 out of 42 (maximum of hyperacusis) and a score greater than 28 seems to represent a strong auditory hypersensitivity. This new psychometric tool should further be tested on hyperacusic patients to verify its relevance in pathology and define the involvement of the three dimensions statistically obtained on the hyperacusis symptomatology.

Adolescent↗
PubMedDate not supplied

Auditory brainstem evoked responses and attention. Contribution to a controversial subject.

The clinical usefulness of the brainstem evoked response (BAER) derives from the high inter- and intra-subject reproducibility of V-wave latency. Attentiveness represents one possible cause of variation. To evaluate the effect of auditory or visual attention tasks and their repetition, we recorded BAERs during six repetitions of each of these two tasks. Each BAER was evoked by 2 000, 40 dB Hearing Level clicks. The results show that, at the 0.05 level, the difference in V-wave latency for auditory and for visual tasks is not significant. Moreover, repetition of the attention tasks fails to bring about any significant (p less than 0.05) change in this difference. In agreement with some researchers, but not with others, we show that attentiveness has little effect on BAER V-wave latency.

Adult↗
PubMedDate not supplied

Maturational changes in the intensity latency relation of the brainstem auditory evoked potentials in humans.

The effects of stimulus intensity variation on brainstem auditory evoked potentials have been studied on 111 preterm, 36 fullterm neonates and 50 adults. When intensity decreases the lengthening of latencies is greater in preterm neonates. This effect is clearer with wave I than waves III and V and suggests an immaturity of the basal part of the human cochlea in preterm neonates.

Acoustic Stimulation↗
PubMedDate not supplied

Auditory-evoked brainstem responses elicited by maximum-length sequences in normal and sensorineural ears.

Auditory brainstem responses (ABRs) were recorded using pseudo-random pulse trains called maximum-length sequences (MLSs), which allow high stimulus rates and simultaneous recording from both ears, and were compared to ABRs obtained by conventional averaging. In normally hearing subjects, ABRs by MLSs produced the same waves as conventional ABRs, although wave latencies increased and amplitudes decreased. In normal as in sensorineural ears, MLS-ABR thresholds were similar to conventional ABR thresholds (except when binaural recordings were made) and were correlated with high-frequency audiometric thresholds. Binaural MLS-ABR recordings represent the individual response of each ear, as shown by recordings of monaurally deaf subjects.

Acoustic Stimulation↗
PubMedDate not supplied

Distortion product otoacoustic emissions and sensorineural hearing loss.

As other types of otoacoustic emissions, distortion product otoacoustic emissions (DPOAEs) allow the exploration of the active cochlear mechanisms known to take place in the outer hair cell system. Most authors consider that 2f1-f2 DPOAEs are generated in a cochlear region corresponding to the geometric mean (GM) of the primary frequencies. To verify the relevance of this hypothesis in clinical practice, DPOAEs were recorded at seven different frequencies, ranging from 0.5 to 4 kHz, in 81 hearing-impaired patients and in 24 normally hearing subjects. To test the hypothesis that DPOAEs reflect the hearing threshold at the frequency of the GM rather than at the 2f1-f2 frequency, this study compares the 2f1-f2 frequency and the GM of the primaries to the frequency of hearing loss. DPOAEs can be used to explore a large range of frequencies, especially at high frequencies, but responses at low frequencies are less reliable due to noise contamination. Secondly, DPOAEs can be recorded in ears that have a hearing threshold as high as 65 dB HL at the frequency corresponding to the GM of the primaries. Finally, DPOAE recordings show frequency specificity: i.e., hearing loss at a specific frequency correlates best with DPOAEs whose GM of primary frequencies corresponds to the frequency of the hearing loss. However, this frequency specificity is still unsatisfactory and decreases as the levels of primaries increase above 60 dB SPL. Moreover, DPOAE amplitude is too variable to predict hearing loss at a particular frequency, whereas DPOAE threshold allows a correct prediction of abnormal auditory threshold in more than 80% of the cases at frequencies above 1 kHz.

Acoustic Impedance Tests↗
PubMedDate not supplied

2f1-f2 distortion product otoacoustic emission latency: changes with frequency and level of primaries.

Distortion product otoacoustic emissions (DPOAEs) provide a non-invasive and relatively direct method for evaluating cochlear travel time in humans. In the present study, the 2f1-f2 DPOAE latency was deduced from DPOAE phase shift according to f2 frequency shift, with f1 being fixed, using the ILO92 system. Latencies of 2f1-f2 DPOAEs were recorded at various primary frequencies and levels. Results were not wholly consistent with previous latency estimates. This study showed that the functions describing both 2f1-f2 DPOAE latency decrease with primary frequency increase, at several primary-tone levels, and 2f1-f2 DPOAE latency decrease with primary-level increase, at various frequencies, are best fit by exponential equations. The results of the evaluation of the latency-frequency-level relationship indicated the possibility of linking these three variables by the following expression: Latency = 68.30 exp (-0.027I -0.000434 f)+1.13.

Acoustic Stimulation↗
PubMedDate not supplied

Effect of signal duration on categorical loudness scaling in normal and in hearing-impaired listeners.

The present study sought to determine whether the duration of white-noise bursts affects their loudness category rating in the same way for hearing-impaired as for normally-hearing subjects. Twelve normally-hearing and 12 hearing-impaired subjects took part. Categorical loudness growth functions were obtained for 16.25 ms, 32.5 ms, 75 ms, 150 ms and 300 ms white noise bursts. Temporal integration of loudness was defined as the intensity difference needed for stimuli of different durations to result in identical category ratings. In normally-hearing subjects, temporal integration of loudness occurred mainly with the short-duration (16.25 ms and 32.5 ms) stimuli, whereas it was found with almost every stimulus duration in hearing-impaired subjects. In other words, temporal integration of loudness between 16.25 ms and 300 ms stimulus duration was greater in hearing-impaired listeners and there was a difference between normal and hearing-impaired subjects regarding change in loudness perception with stimulus duration. Consequently, the use of fixed-duration stimuli hinders loudness normalization.

Adolescent↗
PubMedDate not supplied

Auditory brainstem response (ABR) latency: relative importance of age, sex and sensorineural hearing-loss using a mathematical model of the audiogram.

Influences of age, sex and audiogram on ABR latencies have been studied. Using a mathematical model of audiogram, the analysis of data finds a relative importance of age, sex and audiogram similar to previous studies. Audiogram slope was correlated only with the latencies of waves I and V, and multiple regression analyses indicate the slope effect is relatively weak compared to that of the other parameters. Using a mathematical model of audiogram did not improve the ABR variance across subjects, underscoring the need to discover other relevant variables to explain ABR latency.

Acoustic Stimulation↗
PubMedDate not supplied

Differential maturation of brainstem auditory evoked potentials in preterm infants according to birthweight.

Brainstem auditory evoked potentials (BAEPs) were recorded from 39 preterm infants, divided into 3 groups: small-for-gestational-age, with a birthweight less than or equal to 1500 g (SGA); appropriate-for-gestational-age, with a birthweight less than or equal to 1500 g (AGA1); and appropriate-for-gestational-age, with a birthweight higher than 1500 g (AGA2). A significant shortening of the I-V interval due to an increase in wave I latency was found in the SGA group. The lower-weight AGA group (AGA1) was never significantly different from the SGA group. Although there was no correlation between conceptional age and weight at the time of the examination for the studied population, negative correlations were found between wave I latency and weight at the time of the examination. These findings confirm previous research and suggest the existence of a link between weight and basal cochlear maturation.

Acoustic Stimulation↗
PubMedDate not supplied

Contralateral auditory stimulation and otoacoustic emissions: a review of basic data in humans.

The influence of contralateral auditory stimulation on otoacoustic emissions (OAE), spontaneous OAE, evoked OAE and acoustic distortion products, can be summarized as follows: (1) alteration (mainly a decrease) of OAE amplitude; (2) alteration of response spectrum (upward shift frequency of SOAE); (3) alteration of phase; (4) effect dependent on intensity of contralateral stimulation; (5) effect inversely dependent on intensity of ipsilateral stimulation; (6) frequency specificity of the suppressive effect. Involvement of the medial olivocochlear bundle is highly probable but one cannot exclude a double pathway including also the acoustic reflex.

Acoustic Stimulation↗
PubMedDate not supplied

[Otoacoustic emissions in the human].

Otoacoustic emissions are sounds emitted by the cochlea, basically deriving from the active micromechanical properties of the outer hair cells of the organ of Corti. As they can be recorded painlessly and non-intrusively, they provide a good means of studying human cochlear functioning. In this report, the main types of otoacoustic emission are described, with their characteristics and relation to cochlear functioning. The contribution of otoacoustic emission studies to the physiology of the medial olivocochlear system is discussed, this being the only sensitive and non-intrusive way of studying this system, the function of which remains uncertain.

Acoustic Stimulation↗
PubMedDate not supplied

[The shortened Beck depression inventory (13 items). Study of the concurrent validity with the Hamilton scale and Widlöcher's retardation scale].

The present study on 50 depressed subjects (Research Diagnostic Criteria of Feighner) has shown on the one hand a weak correlation between the shortened Beck Depression Inventory (BDI) and the Hamilton Depression Rating Scale and on the other hand of the shortened Beck Depression Inventory and the Widlöcher Retardation Rating Scale. Both correlations do not differ significantly.

Depressive Disorder↗
PubMedDate not supplied

Predictive value of MMPI scales on smoking cessation programs outcomes.

Five hundred and fifty-eight cigarette smokers were randomized in 4 groups: acupuncture, behavior therapy, placebo and waiting list. The MMPI scales showed stability across pretest, posttest and a one-year follow-up. Principal components analysis isolated a "depression-psychasthenia" factor accounting for 61% of the variance. Moreover 43% of the subjects had an abnormal MMPI profile. Segmentation isolated predictive factors: a high number of pathological MMPI scales predicted failures in any kind of treatment. Acupuncture yielded better outcomes when the profiles were normal. Behavior therapy and placebo had better outcomes when the anxiety index was abnormal. The study underscores the role of personality factors in tobacco addiction and their influence on cessation programs outcomes.

Acupuncture Therapy↗