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Biomedical subjects

L Carlson-Sabelli

Publications and source records attributed to L Carlson-Sabelli.

5 recordsLinked to original sources

Bios data analyzer.

The Bios Data Analyzer (BDA) is a set of computer programs (CD-ROM, in Sabelli et al., Bios. A Study of Creation, 2005) for new time series analyses that detects and measures creative phenomena, namely diversification, novelty, complexes, nonrandom complexity. We define a process as creative when its time series displays these properties. They are found in heartbeat interval series, the exemplar of bios .just as turbulence is the exemplar of chaos, in many other empirical series (galactic distributions, meteorological, economic and physiological series), in biotic series generated mathematically by the bipolar feedback, and in stochastic noise, but not in chaotic attractors. Differencing, consecutive recurrence and partial autocorrelation indicate nonrandom causation, thereby distinguishing chaos and bios from random and random walk. Embedding plots distinguish causal creative processes (e.g. bios) that include both simple and complex components of variation from stochastic processes (e.g. Brownian noise) that include only complex components, and from chaotic processes that decay from order to randomness as the number of dimensions is increased. Varying bin and dimensionality show that entropy measures symmetry and variety, and that complexity is associated with asymmetry. Trigonometric transformations measure coexisting opposites in time series and demonstrate bipolar, partial, and uncorrelated opposites in empirical processes and bios, supporting the hypothesis that bios is generated by bipolar feedback, a concept which is at variance with standard concepts of polar and complementary opposites.

Creativity↗

Process theory as a framework for comprehensive psychodynamic formulations.

In this article, we have proposed a method for developing integrative psychiatric formulations based on process theory, as contrasted to eclectic attempts to combine separate, often disparate, theories. Congruent with chaos theory and "far from equilibrium" thermodynamics, process theory proposes that normal development and psychopathology are creative processes open to chance, choice, and meaningful coincidences and governed by harmonious and conflictual interactions between opposites. We have illustrated our method by discussing a case, previously described by Perry, Cooper, and Michels (1987) from three psychoanalytic perspectives. We interpret this case to result from a possible neuroamine depletion, poor family life, social defects, and habitual conflictual/depressive patterns of interaction.

Brain↗

The thermodynamics of bipolarity: a bifurcation model of bipolar illness and bipolar character and its psychotherapeutic applications.

Two models dominate current formulations of bipolar illness: the homeostatic model implicit in Freud's psychodynamics and most neuroamine deficit/excess theories; and the oscillatory model of exaggerated biological rhythms. The homeostatic model is based on the closed systems approach of classic thermodynamics, while the oscillatory model requires the open systems approach of modern thermodynamics. Here we present a thermodynamic model of bipolarity that includes both homeostatic and oscillatory features and adds the most important feature of open systems thermodynamics: the creation of novel structures in bifurcation processes. According to the proposed model, bipolarity is the result of exaggerated biological energy that augments homeostatic, oscillatory and creative psychological processes. Only low-energy closed systems tend to rest ("point attractor") and entropic disorder. Open processes containing and exchanging energy fluctuate between opposite states ("periodic attractors"); they are characteristic of most physiological rhythms and are exaggerated in bipolar subjects. At higher energies, their strong fluctuations destroy pre-existing patterns and structures, produce turbulence ("chaotic attractors"), which sudden switches between opposite states, and create new and more complex structures. Likewise, high-energy bipolars develop high spontaneity, great fluctuations between opposite moods, internal and interpersonal chaos, and enhanced creativity (personal, artistic, professional) as well as psychopathology (personality deviations, psychotic delusions). Offered here is a theoretical explanation of the dual--creative and destructive--nature of bipolarity in terms of the new enantiodromic concept of entropy generalized by process theory. Clinically, this article offers an integrative model of bipolarity that accounts for many clinical features and contributes to a definition of the bipolar personality.

Adult↗

Biological priority and psychological supremacy: a new integrative paradigm derived from process theory.

Process theory is a comprehensive theory of physical and psychological processes that can serve to integrate biological, social, and psychodynamic psychiatry. Process theory uses concepts derived from mathematical dynamics and Heraclitus's process philosophy. It provides three novel and clinically applicable concepts: 1) biological priority and psychological supremacy (as contrasted to theories of biological or psychological primacy), 2) union of opposites (as contrasted to psychoanalytic and dialectic conflicts and to systems homeostasis), and 3) creative bifurcations (as contrasted to determinism and developmental theories).

Biological Psychiatry↗