Search PubMed⌕ Search

Biomedical subjects

L C Vaughan

Publications and source records attributed to L C Vaughan.

At least 37 records · Page 2Linked to original sources
PubMed1976

Growth plate defects in foals.

Local disorders of bone growth form an important group of the orthopaedic problems that occur in foals. The recognition of the condition presented is essential so that the appropriate corrective measures may be instituted, and an accurate prognostication made. A knowledge of the applied anatomy of the growth plate is essential to the understanding of these cases. Consideration is given to epiphyseal separation and to angular deformity, from the point of view of diagnosis, prognosis and treatment.

Animals↗
PubMed1976

Experimental cellular allergic reactions in normal canine and malignant human prostate.

This paper describes the histopathology of chronic tuberculin-type hypersensitivity reactions in the normal canine and malignant human prostate. Seven dogs were sensitized by injection of Freund's complete adjuvant and the histological response to the subsequent intra-prostatic injection of 6 mg tuberculin PPD was documented. A chronic mononuclear cell prostatis persisted for 4 weeks and was accompanied by paracortical distension and follicular hyperplasia in regional lymph nodes. Six patients with carcinoma of the prostate were given multiple intraprostatic injections of BCG, which induced a chronic mononuclear cell prostatitis with some evidence of tumour-cell necrosis. The study indicated that the prostate can support chronic cell-mediated allergic reactions to extrinsic antigens and that intra-prostatic injections of BCG can be administered without harmful effects to patients with malignant prostatic disease.

Adenocarcinoma↗
PubMed1975

Surgical remodelling of the femoral trochlea: an experimental study.

Surgical deepening of the groove in the femoral trochlea is a technique commonly employed in the correction of patellar dislocation in dogs. In order to discover how this deep articular defect repairs the operation was studied experimentally in young goats. Observations were made on the appearance of the trochlea and the histologic changes that had taken place after approximately six, 12, and 40 weeks. The abraded groove became filled with fibrocartilage with a relatively smooth surface and it articulated freely with the patella. The majority of the replacement tissues arose by differentiation of the granulation tissue which initially filled the groove, but there appeared to have been some contribution made by the hyaline cartilage at the margins of the groove.

Animals↗
PubMed1975

Arthritis of the canine stifle joint.

A survey of cadaver material was undertaken in order to determine the prevalence of arthritis of the canine stifle joint. One hundred and fifty unselected cadavers were obtained from veterinary practices for this purpose, and their stifle joints were radiographed and dissected to discover abnormalities. Thirty-one dogs (20 per cent) had stifle arthritis and in all except one the lesions were characteristic of osteoarthritis. In the exceptional case infection was the cause. A mechanical derangement was present in 20 of the 54 affected joints, in the form of rupture of the anterior cruciate ligament (10), meniscal tears (9) and patellar dislocation (1). The cause of the arthritis in the other 33 joints is unknown.

Animals↗
PubMed1975

Pectineus muscle resection as a treatment for hip dysplasia in dogs.

Pectineus muscle resection was performed on 100 dogs with hip dysplasia. The degree of dysplasia was estimated by radiography and by joint manipulation. The effects of the procedure on 81 dogs were determined by personal reinspection (34), or by means of owner-reports (47). Improvement was noted in 80 per cent but only 35 per cent reached a high level of recovery. The operation has a role in the treatment of hip dysplasia but it does not cure the condition and it will be several years before the long-term results are known.

Animals↗
PubMed1971

Leg weakness in pigs.

Explore the source record for details and available documents.

Animal Nutritional Physiological Phenomena↗