Scabies: a cause of generalized urticaria.
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Biomedical subjects
Publications and source records attributed to L C Parish.
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The histologic studies of the decubitus ulcer spectrum, which include blanchable erythema, nonblanchable erythema, decubitus dermatitis, decubitus ulcer, and the black eschar/gangrene reveal a dynamic process. The initial change occurs in the vessels of the papillary dermis. This is followed by necrosis of skin structures. The eschar/gangrene represents a full-thickness defect due either to prolonged ischemia and anoxemia or a sudden large vessel occlusion caused by shearing injury.
Skin infection occurs in any age-group, sex, and race but is particularly common in children. It is usually minor, but may indicate underlying systemic disease or may lead to systemic infection. Streptococci and staphylococci are common causes. Group A beta-hemolytic streptococci account for the majority of streptococcal infections in man. Infection most often involves the lower extremities and produces spreading erythema and necrosis but little purulence. Staphylococcal infections most commonly involve the face, the hair follicles and eccrine sweat ducts being the initial sites. Lesions appear as bullae and pustules with a narrow rim of erythema. Intense cellulitis surrounding the lesions usually points to a virulent, penicillin-resistant strain of Staphylococcus. Treatment of both types of infection consists of cleansing with antibacterial agents, removal of crusts, application of warm compresses, and use of topical or systemic antibiotics, depending on the severity of the infection and the type of pyoderma involved.
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A double-blind, multiclinic, parallel, controlled study was conducted to compare the efficacy of two coal tar over-the-counter products, Oxipor VHC lotion and Tegrin lotion. The pooled analysis showed that both left and right sides of the body were comparable with respect to the initial severity of all clinical parameters including scaling, erythema, pruritus, crusting, and lesion elevations. Both test medications improved clinical symptoms significantly, but Oxipor VHC lotion was superior to Tegrin lotion in all clinical variables with the exception of crusting. Oxipor VHC was also significantly superior to Tegrin in terms of physicians' and patients' overall assessments.
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