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Biomedical subjects

L C Cuce

Publications and source records attributed to L C Cuce.

5 recordsLinked to original sources

Scintigraphic evaluation of mycetoma.

Mycetoma is a rare deep mycosis caused by certain fungi. Clinical findings include enlargement and tumefaction of the affected region accompanied by grains coming out of the lesions. The feet are the most frequently affected area. Four patients have been studied who presented with mycetoma of the feet. Gallium scintigraphy was always abnormal in the affected areas and bone scintigraphy was abnormal in three of the four patients. The patient who had a normal bone study had received effective treatment (7 years). In the other patients the results were poor. Scintigraphic findings seem to be similar to those noted in cases of acute osteomyelitis associated with cellulitis, despite long-term therapy. Bone and gallium studies may be of possible value for therapy follow-up in cases of mycetoma.

Adult↗

Activation of human complement system in paracoccidioidomycosis.

Plasma samples of 14 patients with paracoccidioidomycosis were analysed for components that represent activation of the complement system. Most patients (12/13) showed significant titres of complement-fixing antibodies and 14/14 had increased C4d/C4 ratios. There was no conclusive correlation between these two immunological indices, however. Factor B values of patients were similar to normal donors and fragment Ba was not detected in any of the patients. These results indicate a classical complement pathway activation in the plasma of patients with paracoccidioidomycosis.

Adolescent↗

[Botryomycosis].

Four cases of botryomycosis are presented. All patients had fistulous and ulcerated lesions of the lower limbs. Diagnosis was based on the clinical and laboratory findings (presence of grains on direct microscopy examination and positive bacterial cultures). All patients had osteomyelitis. Three were treated with antibiotics or sulfonamides (orientated by the antimicrobial susceptibility test) and were cured.

Adult↗

[Paracoccidioidomycosis. Accidental inoculation "in anima nobile." Report of a case].

A case of paracoccidioidomycosis by accidental innoculation on the back of the left hand in a female patient is presented. Clinically the manifestation was of a hard and painful nodular lesion. This lesion was completely excised surgically. This lesion was completely excised surgically. The material obtained revealed the "Paracoccidioides brasillensis" by direct and histopathologic microscopic examinations. No culture was obtained. The histopathologic aspect of the lesion was of a tuberculoid granuloma. The immunological study demonstrated a positive intradermic test and negative results by complement fixation and preciptin reactions. The lesion cured completely after the surgical excision and sulfadimetoxin treatment.

Adult↗