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Biomedical subjects

L Brunereau

Publications and source records attributed to L Brunereau.

54 records · Page 3Linked to original sources

Idiopathic granulomatous hypophysitis: clinical and imaging features.

Idiopathic pituitary granuloma is a rare disorder similar to lymphocytic adenohypophysitis. Few cases have been reported. We report a new histologically case proven with MRI. The patterns of clinical and radiological presentation and the management of this disorder are discussed. MRI findings suggestive of this condition include an intensely enhancing pituitary mass, associated with dural enhancement. Steroid therapy may be suggested avoiding unnecessary surgery.

Adenoma↗

Cerebral infarction associated with vasculitis due to varicella zoster virus in patients infected with the human immunodeficiency virus.

Cases of herpes zoster ophtalmicus (HZO) with delayed contralateral hemiparesis caused by hemispheric stroke secondary to granulomatous angiitis have been reported and are a well-recognized complication of herpes zoster. Similar cases have been reported more recently during infection with human immunodeficiency virus (HIV). We describe two HIV+ patients without any clinical history of zoster dermatitis who developed a sudden hemiparesis followed 2 weeks later for one by an acute retinal necrosis. Computerized tomography (CT) scan, magnetic resonance imaging (MRI), magnetic resonance angiography (MRA), and digital subtraction angiography (DSA) were performed and showed a hemispheric stroke with evidence of a segmental arteritis of the carotid syphon. Varicella zoster virus (VZV) was found in the cerebro spinal fluid (CSF) in the two patients and after puncture of the vitreous fluid of the patient with the acute retinal necrosis. These two cases exemplify the difficulty of diagnosis of stroke in HIV+ patients, which seems to be more frequent than in similarly aged non-infected patients and demonstrates that VZV needs to be taken in consideration and identified even without any past history of zoster dermatitis.

AIDS-Related Opportunistic Infections↗

[Hemangiomas and superficial vascular malformations of the head and neck. Classification, diagnosis, treatment].

Each kind of superficial vascular malformation (or "angioma") has been included in a widespread classification that has been elaborated by means of a multidisciplinary approach. At present, therapeutic management of these vascular malformations often needs one or several procedures of interventional radiology. The purpose of this paper in to illustrate embolization techniques in each indication and to describe advantages and drawbacks of these different techniques.

Diagnosis, Differential↗

[Imaging of ORL diseases in acquired immunodeficiency syndrome].

More than 50% of patients with acquired immunodeficiency syndrome (AIDS) present a lesion affecting parotid gland, lymph nodes, paranasal sinuses, pharyngo-larynx or temporal bone. In about 20% out of cases affected patients present different head and neck lesions at the time of evaluation. Most often, clinical examination and endoscopy are sufficient to perform diagnosis and to manage the disease. Imaging studies (CT or MRI) are indicated when the nature of the disease is unknown or when a map of the process is mandatory for therapeutic approach. Some imaging features are strongly suggestive of HIV infection: parotid cysts associated with hyperplasia of the nasopharynx and cervical lymph nodes enlargement; labyrinthitis and multinevritis; and head and neck squamous cell carcinomas in non alcoolo-tobacco addicted patients. Such diseases suggest the need for knowledge of the patient's seropositivity status.

Acquired Immunodeficiency Syndrome↗

[Persistent facial paralysis: contribution of imaging to identification of perineural infiltrating tumor].

To describe imaging features suggestive of retrograde perineural spread in progressive facial palsy without known tumoral origin. Two reports of perineural infiltration by salivary malignant tumors were diagnosed on abnormal enhancement of the facial nerve associated with an abnormal nerve enlargement (1/2). These unsuspected tumors were located in parotid gland (1/2) and the sub-maxillary gland (1/2). ENT tumors (especially adenoid cystic carcinomas) should be carefully searched in case of perineural spread, as these tumors may be misdiagnosed due to their size, location and signal. Therefore, imaging studies of facial palsy should include temporal bone, skull base, parotid gland, submaxillary gland and sub cutaneous areas of the face. A sub-maxillary gland tumor should be searched in case of facial palsy associated with glossodynia.

Carcinoma, Adenoid Cystic↗

Rhinoscleroma with orbital extension: CT and MRI.

We describe the MRI features of a rhinoscleroma with orbital extension. This benign bacterial and granulomatous lesion of the paranasal sinuses gave homogeneous low intensity on T2-weighted images and enhanced with gadolinium. It could simulate a malignant sinonasal tumour or a fungal sinusitis; the diagnosis must be considered in patients from endemic areas.

Adult↗

[Cerebral arteritis in AIDS. Demonstration with MRA in 2 patients].

Two cases of cerebral arteritis related to varicella-zoster virus in seropositive patients are presented. Diagnosis of arteritis was made by conventional angiography. However, 3D Time of Flight MR Angiography demonstrated an excellent sensitivity in detection of cerebral arterial stenosis located at the skull base.

AIDS-Related Opportunistic Infections↗

Intracranial dural arteriovenous fistulas with spinal venous drainage: relation between clinical presentation and angiographic findings.

PURPOSE: To investigate why some patients with an intracranial dural arteriovenous fistula (DAVF) with spinal venous drainage have myelopathy and others do not. METHODS: We reviewed the clinical and radiologic data for 12 patients who had a DAVF with spinal venous drainage diagnosed at our institutions from 1982 to 1995. RESULTS: Six patients had progressive spinal cord indications of disease (patients with myelopathy) and six others (patients without myelopathy) had cerebral indications (five had intracranial hemorrhage and one had a seizure). Cerebral angiography showed a posterior fossa DAVF with spinal venous drainage in all cases. The clinical presentation of DAVFs with spinal venous drainage was compared with the extent of the drainage. In patients without myelopathy, the spinal venous drainage exited the intradural canal via the cervical medullary-radicular veins and was therefore limited to the cervical perimedullary veins. In patients with myelopathy, no medullary-radicular vein was seen, and the venous drainage descended along the perimedullary veins of the entire spinal cord toward the conus medullaris. CONCLUSION: We found an exact relation between clinical presentation and venous drainage of DAVFs with spinal venous drainage. Patients had no myelopathy when the venous drainage was limited to the cervical cord; myelopathy was present when the venous drainage descended toward the conus medullaris.

Adult↗

[Anatomy of the circle of Willis with 3D time of flight magnetic resonance angiography and analysis of partitions].

The purpose of this study was to analyse with 3D TOF MR angiography the anatomical variants of the circle of Willis (CW) in 109 consecutive patients. In all cases, the quality of exams was sufficient to analyse the anatomy of CW. Nevertheless, MRA over estimated hypoplastic segments because incomplete CW were more frequently demonstrated with MRA than in anatomic literature. This lack of MRA sensitivity was related to artifacts as MIP artifacts and blood flow artifacts. MRA sensitivity was improved by analysis of partitions with MIP reconstructions.

Aged↗

[Imaging of cerebral thrombophlebitis].

Because of the polymorphic nature of the clinical presentations observed, the diagnosis of cerebral vein thrombosis (CVT) is often difficult and based on the findings of various imaging techniques. Routine CT scan constitutes a guiding examination allowing exclusion of other diseases responsible for the clinical symptoms and signs. MRI, a noninvasive technique allowing analysis of perfusion and thrombosis would appear to be the first-line examination for diagnosis as well as follow-up. The development of MR angiography techniques now allows confirmation of the diagnosis of dural sinus occlusion. However, certain false-negatives may be observed with MRI, especially in the case of cortical vein thrombosis. When doubt persists concerning the diagnosis, cerebral angiography remains the reference examination.

Cerebral Angiography↗

[Parotid metastases: value of imaging. Review of the literature, apropos of 4 cases].

Parotid gland is a very unusual site of metastasis. Four proven cases are described. The tumor was occult in three cases out of four. In one case, an extra neck primitive tumor was suspected. Two kinds of metastases are described: firstly, metastases within the salivary gland with look like pleomorphic adenoma and are secondary to hematogenous spread; secondly, lymph node metastasis (two cases). Their diagnosis appear easier as they are not usually completely surrounded by parenchyma. They can reveal either occult head and neck tumor or visceral tumor.

Adult↗

[Uncommon presentation of thyroid cancer].

Thyroid carcinomas are rare. Papillary carcinomas are the most frequent and preferentially spread via lymphatics. Cervical lymph node metastases are common and may be the presenting sign of the disease, when thyroid carcinoma is occult.

Adult↗

[Organized follicular cyst simulating a sinus lesion].

Follicular cyst is a frequent lesion rich in cholesterine and methemoglobin. These cysts produce T1 shortening and a high intensity signal on T1-weighted imaging. The most frequent location is the lower mandibular ramus. Sometimes, it occurs in the maxillar with possible involvement of the paranasal sinuses simulating a mucocele or a space-occupying lesion of the sinus.

Diagnosis, Differential↗

Prospective evaluation of time-of-flight MR angiography in the follow-up of intracranial saccular aneurysms treated with Guglielmi detachable coils.

PURPOSE: The purpose of our study was to prospectively evaluate 3D time-of-flight (TOF) MR angiography (MRA) in the follow-up of 27 intracranial aneurysms treated with Guglielmi detachable coils (GDCs). METHOD: From February 1997 to June 1998, 26 patients with 27 aneurysms were included in this prospective study. Aneurysms were located in the anterior circulation in 23 cases and in the posterior circulation in 4 cases. All patients underwent 3D TOF MRA and digital subtraction angiography (DSA) in the same week within 4 months after aneurysmal treatment with GDCs. No clinical events occurred during the follow-up. We analyzed residual flow within the coil mass and within the aneurysmal neck and the patency of the parent and adjacent arteries on MRA and DSA. MRA analysis was based upon MIPPED and source images. DSA was our gold standard. RESULTS: In all cases, the quality of MRA was good enough to be informative. In aneurysmal analysis, the sensitivity, specificity, positive predictive value, and negative predictive value of MRA were, respectively, 80, 100, 100, and 96% to diagnose residual flow within the coil mass (one false-negative case) and 83, 100, 100, and 95.5% to diagnose residual flow within the aneurysmal neck (one false-negative case). In arterial analysis, sensitivity and positive predictive value of MRA were 89 and 100% to diagnose patency of the parent artery (three false-negative cases) and 83 and 100% to diagnose patency of adjacent arteries (seven false-negative cases). CONCLUSION: In the follow-up of intracranial aneurysms treated with GDCs, 3D TOF MRA could be used as a screening test to select patients that should undergo DSA and thus could improve patient follow-up in terms of risk-benefit.

Adult↗