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Biomedical subjects

L Brodsky

Publications and source records attributed to L Brodsky.

At least 91 records · Page 5Linked to original sources
PubMed1986

Mortality among ferrous foundry workers.

Mortality analyses were carried out for 278 male hourly workers who were employed for at least 10 years at a gray iron foundry and who died between January 1, 1970 and December 31, 1981. Statistically significant excess proportional mortality due to non-malignant respiratory disease (SPMR = 177), lung cancer (SPMR = 148), and leukemia (SPMR = 284) was found among the 221 white males. Among nonwhite males there was a significant excess in proportional mortality due to circulatory diseases (SPMR = 143). White males in the Finishing classification experienced a significant excess of proportional mortality due to nonmalignant respiratory disease (SPMR = 279) and lung cancer (SPMR = 179). White males in the Core Room classification experienced an excess of proportional mortality due to nonmalignant respiratory disease (SPMR = 321). Case-control studies demonstrated a significant association between nonmalignant respiratory disease and the Finishing classification after controlling for the effects of age, prior occupations in coal mining or foundries, and smoking. A positive but nonsignificant association between lung cancer and Finishing was also found after controlling for age, prior work history, and smoking in case control studies.

Adult↗
PubMed1986

Histopathological changes in distal tracheal mucosa in beagle puppies.

Direct effects of the tracheotomy tube and cuff on glottic, subglottic and tracheal mucosa have been well described. Little work has been done on the effects of tracheotomy on the distal tracheobronchial tree. Ten beagle puppies underwent tracheotomy and were sacrificed at 18, 24, 36, 48 and 72 h. The trachea was studied for changes in cilia, epithelium, submucosal reaction and mucous production at the level of the tracheostome, tracheotomy tube tip, carina and right mainstem bronchus. Severe changes of epithelial erosion and ulceration with submucosal inflammatory reaction were noted as early as 18 h and persisted through 24 h. Some resolution of inflammation and progression to squamous metaplasia were seen at 36, 48 and 72 h. Changes in mucous gland activity varied widely. The traumatic effects of tracheotomy on normal tracheal anatomy and physiology and their clinical implications are discussed.

Animals↗
PubMed1985

Sensorineural hearing loss following live measles virus vaccination.

Infection with measles virus is a well-known cause of acquired hearing loss in children. Although measles virus vaccination on occasion may result in many of the complications seen with naturally occurring measles, the occurrence of hearing loss following measles virus vaccination has yet to be reported. This is a case report of encephalitis and severe sensorineural hearing loss following a measles virus vaccination.

Child, Preschool↗
PubMed1985

The use of antidepressants in a psychiatric emergency department.

This article is the result of a pilot program at Sinai Hospital of Detroit's psychiatric emergency department (crisis clinic). Eight patients diagnosed as having a major depression and having met six proposed criteria were placed on antidepressant therapy. This approach contradicts traditional thinking regarding the initiation of antidepressant therapy in an emergency department or crisis clinic. Such use of antidepressants has, in the past, been considered unsafe and therefore contraindicated. This article suggests a protocol for the initiation of antidepressant therapy in an emergency department.

Adult↗
PubMed1984

Spontaneous cerebrospinal fluid otorrhea and rhinorrhea coexisting in a patient with meningitis.

Congenital (spontaneous) cerebrospinal fluid fistulae are uncommon, potentially dangerous, pathological conditions. Most present in childhood with repeated bouts of meningitis, although presentation in adulthood with an asymptomatic nasal mass has been well documented. Radiologic work-up of the patient will usually reveal an abnormality in either the labyrinth or the base of the skull. A patient is presented who had both spontaneous cerebrospinal fluid otorrhea and rhinorrhea. Three anatomic defects were identified as potentially accountable: a round window fistula, a meningoencephalocele and an empty sella turcica.

Cerebrospinal Fluid Otorrhea↗
PubMed1983

Post-traumatic facial nerve paralysis: three cases of delayed temporal bone exploration with recovery.

No consensus exists today on the management of immediate-onset post-traumatic facial nerve paralysis. Controversy surrounds the timing of surgical intervention and the role of electrophysiologic testing. Three patients are presented who sustained immediate, complete facial paralysis following closed head trauma. They did not have prompt facial nerve decompression. In each case, electroneurography and electromyography showed complete nerve degeneration and denervated muscle. Despite the results of the electrophysiologic tests, all patients underwent late surgical decompression of the nerve: one at 2 1/2 months, one at 3 months, and one as late as 14 months after injury. They all had good recovery of facial function within 6 months of surgery. Early surgical intervention has been advocated in post-traumatic facial nerve paralysis if any benefit is to be gained. It is thought that late surgical intervention is unlikely to yield further improvement in the facial nerve function. Experience with these cases suggests that surgical exploration of the facial nerve is indicated at anytime, as it may be beneficial even in very old injuries. The prognostic value of electroneurography and electromyography in determining facial nerve recovery and in deciding upon facial nerve surgery is questioned.

Adult↗
PubMed1978

Extension of emergency medical care: continuing emergency care clinic.

An alternative follow-up system, a Continuing Emergency Care clinic (CEC) was developed at The Medical College of Pennsylvania in an attempt to increase emergency department patient compliance for follow-up. One year after the CEC was in operation, in an attempt to determine variables influencing the effectiveness of the clinic, a total of 375 emergency department patients given follow-up appointments to the CEC were studied. Results showed that a change in the structure of the clinic appointment and a shift in the line of responsibility for follow-up care directly to the emergency physician are two major variables positively affecting patient compliance.

Adolescent↗
PubMed1977

Anger provocation as a crisis intervention technique.

The author describes the use of anger provocation, a technique that encourages patients to express their repressed anger to a therapist who makes himself the target for their anger. He presents five case examples to illustrate the positive effects of the technique in crisis and emergency situations. Three of the patients were depressed and withdrawn, one was suffering from conversion hysteria, and one was a paranoid schizophrenic. The author cautions that the technique must be used with discretion only in those cases where the repression of anger is producing major incapacitating symptomatology, but where the anger is not the major source of disorganization.

Abreaction↗