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Biomedical subjects

L Brinquin

Publications and source records attributed to L Brinquin.

At least 37 records · Page 2Linked to original sources
PubMed1998

[Four hours for a record, or a severe fuminating cellulitis: can Saccharomyces cerevisiae be the causal agent?].

A 31-year-old woman presented with a subcutaneous cellulitis which occurred within four hours following a minor wound of a knee. This very short delay could be explained neither by the health state, nor the mechanism of injury, nor the bacteria usually responsible for such a cellulitis. Considering the clinical characteristics (high gas production) and the professional context (wine cellar employee), Saccharomyces cerevisiae, a yeast used for wine or bread production, may explain this complication.

Adult↗
PubMed1997

[Intracranial aneurysm and coronary ectasia].

BACKGROUND: Coronary aneurysms are uncommon and can exceptionally be associated with other aneurysmal localizations. CASE REPORT: A 34 year-old man with a history of aneurysm of the coronary arteries revealed by myocardial infarction without a wave six months earlier, presented cerebral hemorrhage secondary to an aneurysmal rupture of the anterior communicating artery. DISCUSSION: Other aneurysmal localizations such as the abdominal artery, pulmonary artery, hepatic artery, popliteal artery, coronary venous system or the left ventricle have been associated with coronary artery aneurysm. Only one case of coronary and cerebral aneurysm has been previously reported in the literature in an 8-year-old child with X-linked lymphoproliferative syndrome and EBV-induced infectious mononucleosis. Our case suggests that systemic aneurysmal disease may be a clinical entity and that cerebral angiogram should be discussed in patients with a coronary artery aneurysm.

Adult↗
PubMed1997

[Necrotizing cervico-mediastinal cellulitis. Apropos of 3 cases].

OBJECTIVE: To outline the most appropriate treatment of descending necrotizing mediastinitis. MATERIALS AND METHODS: Three adult patients had mediastinitis occurring from a descending odontogenic infection in one case and oropharynx infection in two cases. All patients underwent extensive surgical debridement and a cervicomediastinal drainage through a cervical incision. All patients survived. DISCUSSION: Soft-tissue infections of the neck with mediastinitis demand early diagnosis aided by CT scan in order to decrease their threat to life. Extensive surgical debridement and a cervico mediastinal drainage through a cervical incision is adequate when mediastinitis is limited to the upper mediastinum. Thoracotomy has to be performed when the process spread below the carina. Patients must be treated initially aggressively with the aid of multidisciplinary support team (intensive care physicians, thoracic and head and neck surgeons). Early surgery must treat both neck and mediastin. While usually associated with greater than 40% mortality, all the patients in this series survived.

Adult↗
PubMed1995

[Diffuse toxoplasmic encephalitis in a non-immunosuppressed patient].

Diffuse encephalitic toxoplasmosis is an unusual presentation of toxoplasmosis, in which neuroradiological investigations may not show focal abcesses. Until now it was only reported in immunocompromised patients. In immunocompetent patients, cerebral toxoplasmosis is very unusual, and appears as multiple abcesses, like the classic form in immunocompromised patients. We report the case of an immunocompetent patient who presented a diffuse encephalitic toxoplasmosis; CT and MR examinations showed only nonspecific features of brain swelling and cortical infarct due to vasculitis.

Adult↗
PubMed1994

[Magnetic resonance imaging during the acute phase of severe head injuries].

In 1994, tomodensitometry is indispensable for diagnosis and treatment of acute head trauma. Magnetic resonance imaging (MRI) is more performant but not yet evaluated in this indication. Two homogeneous series of patients allow the authors to discuss interest and feasibility of MRI and to propose a new strategy for reception of acute head trauma.

Adult↗
PubMed1993

[Continuous infusion of vancomycin in post-neurosurgical staphylococcal meningitis in adults].

Eight adult patients with post-surgery meningitis caused by methicillin-resistant staphylococci were treated with continuous intravenous infusion of vancomycin in mean doses of 50 mg/kg/day. This treatment, which lasted 3 to 6 weeks, was well tolerated by the kidneys and resulted in cure in all cases; its effect on the ear was not evaluated. Stable concentrations of 4 to 7 mg/l in cerebrospinal fluid were obtained after the 48th hour of treatment.

Adult↗
PubMed1992

[The value and limitations of autotransfusion in traumatology].

29 autotransfusions were realised in severe cases of trauma (20% of a sample of 143 traumatic emergencies). The recovery of haemothorax blood as well as the peroperative collection by a Cell Saver allowed the retransfusion of 1989 +/- 1,838 ml (225-7070 ml) of autologous blood, amounting to 56% of the average blood loss. A total of 69% of the patients received homologous blood. Eight patients (where the haemorrhage amounted to 143% of the blood volume) showed some coagulation troubles. Autotransfusion assures the immediate availability of blood while reducing the immunological and viral transfusion risks. Therefore haemothorax autotransfusion should be used systematically. Peroperative recollection by a cell-separator works well but is technically more tedious.

Adult↗
PubMed1992

[Methods of reducing peroperative bleeding].

The reduction of bleeding during surgery can be aimed at for two reasons: to facilitate the operation by providing a bloodless field and/or to avoid blood loss requiring compensation by transfusion. These aims can be reached by reducing blood pressure or by acting on blood-clotting. For inducing hypotension sodium nitroprussiate and isoflurane are mainly used. Complex and precise monitoring is required for patient safety. Two drugs have been used to diminish bleeding: desmopressin and aprotinin. With the latter an important reduction (40 to 50%) of the blood loss has been achieved.

Blood Loss, Surgical↗
PubMed1991

MRI and cranial traumas in the acute phase.

The authors have reviewed 12 cases of severe cranial trauma examined by MRI and determine the position of this method in exploration in the acute phase. Since the 1970's, computerized tomography (CT) has completely modified the emergency diagnosis. Intra- and extracerebral blood effusions are readily recognized, but the patient is often in a dangerous situation and little help is obtained from CT which does not detect shearing lesions located in the white matter, the corpus callosum or the brain stem. Early MRI examination performed with gradient-echo sequences provides a better anatomico-clinical correlation, a better prognostic approach and even a new therapeutic approach.

Acute-Phase Reaction↗
PubMed1991

[Spinal cord injury and secondary autonomic function disorders].

Autonomic dysfunction is frequently reported after high level spinal cord injury. These disorders usually occur in the first days and resolve spontaneously within 3 to 6 weeks. Usual clinical aspects are hemodynamic abnormalities and often bradycardia which can lead to death. These dysfunctions rarely reappear during neurological status recovery. In this case report, usual autonomic disorders were noted after a T5 level spinal injury with partial motor lesions. However during motor recovery periods, arrhythmias occurred, including ventricular extrasystoles and bursts of ventricular tachycardia. Physiopathological mechanisms are discussed and regulation changes of sympathetic and parasympathetic autonomic nervous system are evoked.

Adult↗
PubMed1990

[Physical and psychological traumatism. Dialectic of singular tragedy and biology].

A good clinical assessment and a strict hospital's organization characterized essentially by the best climate of cooperation between the different departments permits now to control and to prevent some surgical sequelae. For a long time (approximately the 50's) generalists physicians, psychiatrists, behaviourists, have been limited in diagnosis and treatment afterwards. They could not take preventive measures, because the lack or insufficient acknowledge about this area. In fact, every surgical intervention implies psychic and existential, acute or long term disorders. A briefly summarized clinical case illustrate principles for the practice. The preventive approach of the post-surgical psychic troubles concern a lot of elements related to the patient's environement: social interactions, technic cares, types of drugs, style of relation between the specialized teams and patient, social and professional support and so on... The events, even the apparently minor, have to be enough mastered into the resuscitation's setting. The most important trouble is the "post-traumatic stress disorder" (cf D.S.M. III R), or (in the european traduction) a "névrose traumatique". It is a stress or illness of the whole existence, especially in the case of delayed subtype. The authors emphasize the notion of "second traumatism", often withdrived from social, familial and medical supports.

Adult↗