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Biomedical subjects

L Bozzao

Publications and source records attributed to L Bozzao.

137 records · Page 8Linked to original sources
PubMedDate not supplied

[Computerized tomography in the evaluation of neurologic complications of preventive therapy of acute lymphatic leukemia].

The authors examined by means of computed tomography 12 patients with ALL treated with radiotherapy combined with cytostatic chemotherapy and presenting clinical signs of CNS damage. The CT scan findings are correlated with clinical signs, mainly distinguishing between symptoms of either diffuse or focal damage. An attempt is made in order to evaluate the possible role of Methotrexate and X-Ray therapy in the pathogenesis of the CNS lesions.

Adolescent↗
PubMedDate not supplied

The combined use of radionuclide angiography and Doppler-sonography in the screening of carotid lesions.

The aim of our research is to check if the combined use of radionuclide angiography and Doppler-sonography leads to correct screening of carotid lesions in the neck, independently from the indexes of reliability of the individual examinations. 125 cerebrovascular patients (for a total of 250 carotid studies) were investigated with radionuclide angiography and Doppler-sonography. 100 of these carotids were also angiographically investigated. On the basis combined angioscintigraphic and Doppler results, these patients have been classified in four groups. When both non-invasive examinations result negative, the angiography shows pathological arteries only in 22% of cases. When only radionuclide angiography is positive, the angiography shows pathological findings in 63% of cases: when only Doppler is positive, the angiography confirmation occurs in 72% of cases. Finally, when both non-invasive tests results positive, there is always arterial pathology in the angiography.

Adult↗
PubMedDate not supplied

[Spinal cord angioma].

A 35 years old male began to show, 16 years after a transient paraplegia, the neurological signs of a multifocal damage of the spinal cord, which progressed slowly and irregularly over a period of several months. The diagnosis of spinal cord angioma was suspected on the basis of an increase of cerebrospinal fluid white cells and proteins, and of opaque myelography, and proved by spinal angiography. After surgical excision a transient flaccid paraplegia regressed in two weeks, substituted by a mild spastic paraparesis.

Adult↗
PubMedDate not supplied

Enhanced and unenhanced MR with magnetization transfer in multiple sclerosis.

PURPOSE: To evaluate the use of magnetization transfer and the apparent enhancement of lesions on contrast-enhanced MR images in patients with multiple sclerosis. METHODS: Contrast-enhanced T1-weighted spin-echo MR images obtained in 20 patients with relapsing-remitting multiple sclerosis, with and without magnetization transfer, were evaluated to determine the number of enhancing plaques. Comparison was made with unenhanced T1-weighted magnetization transfer images. Contrast-to-noise ratios were obtained for these lesions on both the enhanced and unenhanced magnetization transfer T1-weighted spin-echo MR images. RESULTS: Ten plaques were considered enhancing only when the enhanced magnetization transfer T1-weighted images (11% or more) were used; however, they were all hyperintense on unenhanced T1-weighted magnetization transfer images. The contrast-to-noise ratios of these lesions were 16.52 for the enhanced images and 15.65 for the unenhanced images. The two values were not statistically different. CONCLUSIONS: In patients with multiple sclerosis, examination with contrast-enhanced magnetization transfer MR images alone may overestimate the number of enhancing plaques.

Brain↗