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Biomedical subjects

L Boissonnot

Publications and source records attributed to L Boissonnot.

22 records · Page 2Linked to original sources

[Spinal cord metastasis of a glioblastoma].

Two years after surgery followed by chemotherapy and radiotherapy of a temporal glioblastoma, a 51 year-old woman presented pluriradicular symptoms ascribed to compression of the left part of the cauda equina. The second operation confirmed the metastatic nature of the compression, and histological investigation proved the similarity of the neoplastic tissues taken from the medullary and cerebral regions. The authors stress the rarity of the clinical forms of medullary metastases of glioblastomas. The factors conducive to this fluid effusion are trauma and ventricular effraction by the original tumour. Neither screening nor prophylactic irradiation seem necessary in view of the low frequency of these metastases.

Brain Neoplasms↗

[Neurologic adverse effects of piperazine].

Piperazine has been used since the end of the nineteenth century as a urine alkalizing agent in gout and more widely in the past thirty years for its antihelmintic properties. It is known for being well tolerated and of low toxicity. However, there are cases, sometimes in particular circumstances, where piperazine causes severe and impressive neurological disorders, which can be totally reversed if the medication is discontinued. The disorders are accompanied by consistent, but similarly reversible, electroencephalographic changes. The etiopathogenesis of these accidents caused by piperazine is discussed.

Aged↗