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Biomedical subjects

L Bodner

Publications and source records attributed to L Bodner.

80 records · Page 5Linked to original sources

The role of interventional radiology in the management of intra- and extra-peritoneal leakage in patients who have undergone continent urinary diversion.

PURPOSE: To assess how radiologic intervention altered the hospital course of patients undergoing continent urinary diversion. METHODS: Thirty-seven consecutive patients with bladder cancer invading the muscular layer were treated with total cystectomy and construction of a continent urinary reservoir. Eleven of 37 patients suffered early and late anastomotic leakage; six had prolonged extraperitoneal leakage at the urethroenteric anastomosis, three had prolonged intraperitoneal pouch leaks, and two had delayed ureteroenteric leaks. Seven of these patients required radiologic intervention. RESULTS: Intervention in the form of drainage catheter manipulation (n = 4), percutaneous nephrostomy (n = 4), or ureteral stent placement (n = 2) resulted in cessation of leakage without surgical intervention in all seven patients. Intraperitoneal pouch leaks were more difficult to control than extraperitoneal leakage and required longer drainage intervals. CONCLUSION: Interventional radiologic procedures played a key role in the management of continent urinary diversion complications, obviating the need for repeat surgical intervention in all instances.

Adult↗

Histochemical characterization of collagen fibers in fibrous overgrowth (irritation fibroma) of the oral mucosa: effect of age and duration of lesion.

In a study of 43 specimens of oral mucosa irritation fibroma, polarization colours of collagen thin (0.8 microm) and thick (1.6-2.4 microm) fibers were recorded in formalin-fixed and paraffin-embedded sections stained with Picrosirius red. Examination of polarization colours of both the 'thin' and 'thick' collagen fibers revealed an increase of yellowish-orange and orange fibers as a function of age in patients over 30 years old (P < 0.05 only in thick fibers). When the polarization colours of thin and thick collagen fibers were recorded as a function of duration of the lesion, there was an increase in the number of yellowish-orange and orange fibers and a decrease in blue-green and green fibers in both thin (P < 0.1) and thick (P < 0.05) populations as the lesion matured. These findings show that increments in both the patient's age and the duration of the lesions increase the amount of collagen fibers which exhibit yellowish-orange and orange polarization colours indicating tighter packing and better alignment of the microfibrils, similar to normal mature collagen. These differences may have an effect on the timing of the surgical excision.

Journal Article↗

Parotid gland secretion of the aging rat.

Saliva secretion stimulated by alpha adrenergic beta adrenergic and muscarinic cholinergic neurotransmitters was evaluated in young adult and old rats. Parotid saliva was collected following methoxamin (METH) (6 mg/kg), isoproterenal (ISO) (30 mg/kg), or pilocarpin (PILO) (7.5 mg/kg) as secretory stimuli. The flow rate and the concentrations of protein, Na+ and K+ were measured. Saliva flow rate was 40%-50% lower (P < 0.01) in old rats following METH and PILO, but there was no difference following ISO stimulation. Saliva of old rats stimulated by METH or PILO contained about 30%-40% more (P < 0.01) protein. Comparable protein levels were in saliva stimulated by ISO. No changes were found in Na+ and K+ concentrations in all saliva samples. These results suggest that the age-related alteration in flow rate is not a general phenomenon, but rather specific and limited to the high flow rate stimulants (alpha-adrenergic and muscarinic-cholinergic). Transport alteration from the circulatory system into the parotid gland may be the underlying mechanism.

Journal Article↗

CT of cystic jaw lesions.

OBJECTIVE: Our goal was to compare the efficacy of CT with that of plain film radiography (PFR) in analyzing the three-dimensional shape and structure of cystic jaw lesions. MATERIALS AND METHODS: Twenty patients with cystic lesion of the jaw were studied by PFR and CT. The three-dimensional outline of the cyst and the distances between the cyst wall and adjacent vital teeth, cortical jaw bone, maxillary sinus, and mandibular canal were estimated on PFR and on CT scans. RESULTS: Computed tomography was superior to PFR in the demonstration of the three-dimensional bony margins of the cyst and in determination of its proximity to adjacent vital structures (p < 0.01, sign test). CONCLUSION: Application of CT is useful for diagnosis and treatment planning of cystic lesions of the jaws.

Adult↗

Impacted primary incisor: report of case.

Impaction of a primary incisor is very rare, with only one previous report in the dental literature. After surgical exposure, the case reported here had a normal course of eruption during follow-up.

Child, Preschool↗

Computed tomography in pediatric oral and maxillofacial surgery.

The use of computed tomography (C.T.) in the diagnosis and management of developmental and pathological conditions of the jaws in children was evaluated. CT was found to be superior to plain film radiography in estimation of the three-dimensional morphology of the abnormality in the jaws, in determining spatial relationship and proximity to vital structures. It is valuable by allowing accurate planning of the surgical procedure, estimation of the extent of the surgery and prediction of outcome as well as complications and prognosis. CT in the appropriate circumstances, is a very useful diagnostic tool in pediatric maxillofacial surgery. Tissue preservation and precision are of utmost importance, especially in children where many structures have not reached their final dimensions. Careful consideration should be given to risk benefit ratios due to higher exposure to radiation.

Adolescent↗