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Biomedical subjects

L Bodner

Publications and source records attributed to L Bodner.

At least 19 recordsLinked to original sources

Following treatment of myogenous TMD patients with the temporomandibular opening index: an initial report.

Limitation of mandibular movement is one of the cardinal signs of temporomandibular disorders (TMD), usually assessed by measurement of maximum voluntary mouth opening. A new measure of assessing mandibular mobility, the temporomandibular opening index (TOI), is less dependent on variables such as age, gender and ramus length. It has also been found to be useful to categorize patients. This study examined changes in TOI as treatment progressed in a group of myogenous TMD patients. Seven patients with myogenous TMD were included in the study and the TOI determined at 0 and 2 weeks, 1 and 6 months after initiation of treatment. Treatment outcome was assessed on a 4 point scale, 0=none, 1=mild, 2=moderate, and 3=severe. Headache, neckache, pain (joints and muscles) and joint sounds were assessed. Nine patients with no signs or symptoms of TMD were included to obtain a normal TOI. The mean TOI of the patient group was 16.4% (s.d.=11.2%) initially and 3.95% (s.d.=1.0%) at 6 months, while mean treatment scores changed from 12.57 (s.d.=3.05) to 1.43 (s.d.=1.90). The mean TOI of the control group was 3.63 (s.d.=0.74). A paired t-test showed that the TOI decreased significantly with time (P=0.02) while there was a concomitant decrease in treatment score (P=0.0003) over the same period. The TOI may be a useful method of following treatment of this group of myogenous TMD patients.

Adolescent↗

[Metastatic tumor of the jaw--diagnosis and management].

Metastatic tumors to the oral region are not common. The most common primary sources of metastatic tumors to the oral region are the breast, lung and kidney. The breast is the most common primary site for metastatic tumors to the jawbone, whereas the lung is the most common source for metastases to the oral soft tissues. In the jawbones, the most common location is the mandible, with the molar area being the most frequent involved site. In nearly 30% of the cases, the metastatic lesion in the oral region is the first indication of an unknown malignancy at a distant primary site. The diagnosis and management of a case with metastatic tumor to the mandible is described.

Carcinoma↗

Image accuracy of plain film radiography and computerized tomography in assessing morphological abnormality of impacted teeth.

This study compares the image accuracy of computerized tomography (CT) with that of plain film radiography (PFR) in analyzing the 3-dimensional shape of impacted teeth suspected of being malformed. Eighteen patients with 22 malformed teeth were studied by PFR and CT. Crown shape, root shape, crown/root relationship, and tooth inclination and structure were assessed by PFR and CT. CT was found to be superior to PFR in showing the multiplanar shape of tooth crown and root, crown/root relationship, and tooth inclination (P <.001). No difference was found in the representation of tooth structures. The findings demonstrate that CT imaging is useful to diagnose and plan treatment for patients with unerupted and malformed teeth.

Adolescent↗

[The use of cultured mucosal graft for preprosthetic surgery].

The need to cover denuded mucosal surfaces, is common in oral and maxillofacial surgery. This is particularly a problem in preprosthetic surgery. The surgical options are secondary epithelialization, mucosal graft, skin graft or microvascular graft. The most common are mucosal graft and skin graft, however both have drawbacks. The skin graft displays a marked clinical difference as compared with the mucosa in consistency and color and with occasional hair growth. The mucosal graft is generally more suitable, but is limited by the surface available for harvesting. The purpose of this clinical article is to demonstrate the utility of autologous cultured mucosal sheets in preprosthetic surgery.

Cell Culture Techniques↗

Parotid sialolithiasis.

This report documents an unusual case of buccal mucosa swelling due to a giant (25 x 13 mm), parotid duct sialolith. Review of the literature disclosed that this is the largest parotid sialolith ever reported. Diagnostic imaging and treatment are described.

Aged↗

The long-term effect of oromaxillofacial trauma on the function of the temporomandibular joint.

Thirty patients with temporomandibular disorders (TMD) after trauma to the orofacial region were followed for 6 months. They were assessed at 10 days, 1 month, and 6 months. It was found that patients with combined fractures of the mandible and condyle showed more effects on function of the temporomandibular joint after 1 month than patients with condylar fracture only. This difference was not so apparent after 6 months. Patients with trauma but no fracture showed similar effects to those with non-condylar fractures. There was a tendency for arthrogenous patients to develop myogenous problems with time. A group of patients with TMD but no trauma, showed more favourable long-term response to conservative treatment. Long-term follow-up of these patients for TMD problems is recommended.

Adolescent↗

Temporomandibular joint dysfunction in children: evaluation of treatment.

Thirty-eight pediatric patients with temporomandibular joint (TMJ) dysfunction were diagnosed and treated. The etiology for the TMJ dysfunction was trauma in 30 (79%) patients, degenerative joint disease in two (5%) patients, growth disturbances in two (5%) patients and tumor in one (3%) patient. In three (8%) patients the etiology was unclear. The treatment modalities were: non-invasive therapy in 19 (50%) patients, occlusal therapy in 10 (26%) patients and surgical treatment in nine (24%) patients. The reported symptoms of temporomandibular joint dysfunction using the Helkino anamnestic index revealed that, at the initial examination, eight (21%) reported mild symptoms and 30 (79%) severe symptoms. One year later, 33 (87%) reported no symptoms, four (10%) mild symptoms and one (3%) severe symptoms. These differences were significant (P < 0.05-0.01). Maximum mouth opening 1 year after treatment as compared to the initial examination increased (P < 0.05) in all three treatment modalities. Deviation of the mandible on opening, 1 year after treatment as compared to the initial examination, decreased (P < 0.05) in all three treatment modalities. No differences were found between the modalities in both the maximum mouth opening or deviation of the mandible. TMJ dysfunction in children can be effectively treated by non-surgical treatment modalities. Surgery should be considered only when the non-surgical therapies were ineffective.

Adolescent↗

Trigeminal neuropathy: improved imaging with a dental computed tomography software program.

PURPOSE: This study evaluated the use of images obtained by a dental computed tomography (CT) software program in the diagnosis and treatment of trigeminal neuropathy associated with jaw abnormality. PATIENTS AND METHODS: Twelve patients with jaw abnormality associated with trigeminal neuropathy as the presenting symptom were studied by plain film radiography (PFR) and by a dental CT software program (DS) that displays multiple panoramic and cross-sectional views of the mandible and maxilla. The two modalities were compared for delineation of the integrity of mandibular foramen, mandibular canal, mental foramen, incisive foramen, and incisive canal. Also, displacement of the neurovascular bundle was evaluated and scored. RESULTS: The DS was superior to PFR in showing the bony integrity of the foramina and canals in the jaws, as well as the degree of displacement of the neurovascular bundle. CONCLUSION: DS should be the study of choice for evaluating trigeminal neuropathy associated with abnormalities of the jaws.

Adult↗

Osseous regeneration in the jaws using demineralized allogenic bone implants.

Osseous defects of the jaws following trauma, congenital deformity or pathology may show poor osteogenesis and the affected area may never be completely replaced by bone or will show alveolar height loss. The purpose of the present study was to evaluate the effect of allogenic bone implants (ABI) on the osteogenesis of jaw defects. Fifty-two patients (27 males, 25 females) with cystic lesions of the jaws were randomly divided into two groups: Group A underwent enucleation and packing with adsorbable gelatine sponge. Group B underwent enucleation and grafting with ABI. Both groups were evaluated radiographically. The height of the alveolar process was measured directly on the radiography. The density was measured with a digital densitometer. In Group A, the mandibular height at 6, 12 and 24 months postoperatively was 88%, 80% and 78% of the preoperative heights, respectively. In Group B, the heights were 95%, 93% and 90%, respectively. These differences were significant (P < 0.05-0.01). The density in Group B was significantly greater (P < 0.05-0.01) than in Group A at 6 and 12 months postoperatively. The difference at 24 months was not significant. On the basis of these findings, it can be concluded that ABI grafting of jaw defects enhances osteogenesis and prevents alveolar height loss in the mandible. ABI represent an encouraging alternative to autogenous bone grafting.

Adolescent↗

Efficacy of fibrin sealant in patients on various levels of oral anticoagulant undergoing oral surgery.

OBJECTIVE: The purpose of this study was to investigate the efficacy of fibrin sealant in patients on oral anticoagulant therapy undergoing oral surgery with varying degrees of surgical trauma and various intensities of anticoagulation. STUDY DESIGN: A consecutive series of 69 subjects on oral anticoagulant therapy undergoing oral surgery without changing anticoagulation intensity is presented. For each subject, indication for anticoagulation, international normalized ratio on day of treatment (low, 1.0-2.0; medium, 2.1-3.0; high, 3.1-5.0), degree of surgical trauma (on a scale of 1-12), and complications were recorded and correlated. RESULTS: There were 32 (46.4%) patients with prosthetic valves, 23 (33.3%) with atrial fibrillation and rheumatic or ischemic heart disease, and 14 (20.3%) with previous thromboembolism. Twenty (29%) patients were on low-intensity anticoagulation (international normalized ratio, 1.0-2.0), 26 (37.7%) were on medium-intensity anticoagulation (international normalized ratio, 2.1-3.0), and 23 (33.3%) were on high-intensity anticoagulation (international normalized ratio, 3.1-5.0). Each of 39 (56.5%) patients was in surgical trauma category 1, 2, or 3; the remaining 30 (43.5%) patients were in surgical trauma categories 4 through 12. Complications occurred in 3 (4.3%) patients and took the form of minor postoperative bleeding. No correlation was found between complications and international normalized ratio or degree of surgical trauma. CONCLUSIONS: The use of fibrin sealant in oral surgery for patients on oral anticoagulant therapy is safe, and it can be provided in an international normalized ratio range of 1.0 through 5.0 and in a surgical trauma scale range of 1 through 12.

Administration, Oral↗

Characteristics of bone formation following marsupialization of jaw cysts.

OBJECTIVES: To assess bone regeneration following marsupialization of jaw cysts. METHODS: CT with multiplanar reconstruction (MPR) was performed on 23 patients with cysts of the jaws pre-operatively and 3-4 months after marsupialization. The two images were compared for the three-dimensional outline of the cyst, the distance between the cyst and adjacent structures (vital teeth, maxillary sinus, nasal cavity and mandibular canal) and the integrity of the cortex and mandibular canal. The characteristics of the new bone formation were also determined. RESULTS: The outline of the cyst was changed and partially reduced. The distance between cyst wall and adjacent structures was increased. There was remodelling of the cortex and mandibular canal. The new bone formed in the periphery of the cyst showed either a ground glass appearance or radial bone spicules. CONCLUSION: CT with MPR is useful for evaluation of morphological changes and bone formation following marsupialization of jaw cysts. CT with MPR is the technique of choice for the maxilla and the entire body of the mandible and coronal CT for cysts in mandibular angle and ascending ramus. Cysts can be enucleated safely as early as 3 months after marsupialization.

Adult↗

Temporomandibular joint dysfunction in children.

Sixteen pediatric patients with temporomandibular joint (TMJ) dysfunction were successfully diagnosed following appropriately selected imaging methods. The role of radiography in diagnosis of TMJ dysfunction is essential in distinguishing between the osteogenic and non-osteogenic etiologies. Computed tomography (CT) was found to be a valuable imaging method, with advantages over plain film radiography. The treatment modalities considered were: non-invasive therapy, occlusal therapy and surgical treatment. The treatment of choice was dependent on the osteogenic or non-osteogenic etiology. Surgery was considered only when the non-invasive or occlusal therapies were ineffective.

Adolescent↗

Experimental tongue cancer in desalivated rats.

A group of 39 rats underwent excision of the submandibular and sublingual glands and ligation of the parotid ducts through the midventral incision of the neck, while the control group (41 rats) underwent a sham operation. All rats were administered 4NQO in a final concentration of 0.001% in drinking water. At 7, 14, 22 and 28 weeks after administering 4NQO, both groups of rats were killed and their tongues dissected, inspected and then fixed in 10% buffered formalin for histopathological examination. Clinical examination during the first 14 weeks revealed that rats in both groups looked healthy and no differences in body weight were noticed. Afterwards, the average weight gain of the desalivated rats was lower than in the control group (P < 0.01). The number of macroscopic oral lesions increased with time in both groups. However, in the desalivated rats, the first identifiable lesions were seen as early as week 7, whereas in the control group macroscopic lesions were seen only after 22 weeks. Histological examination revealed more affected rats in the desalivated group in the first 14 weeks after administering the carcinogen; lesions showed more severe pathological changes including two cases with evidence of squamous cell carcinoma. The differences between the desalivated groups and control decreased after 22 weeks with almost no differences at the end of the experiment.

4-Nitroquinoline-1-oxide↗

Growth potential of peripheral giant cell granuloma.

PURPOSE: The purpose of this study was to investigate the association of selected demographic, systemic health, and oral health characteristics of patients with large (> 2 cm) peripheral giant cell granuloma and to assess its growth potential and the possible underlying causes. METHODS: A series of 79 cases including 15 subjects with lesions 2 to 5 cm in the largest diameter is presented. Age, sex, site, size, systemic health, oral hygiene, and report of oral dryness of subjects with large lesions were compared with those of subjects with small lesions (< 2 cm). RESULTS: No differences were found in mean age between the small lesion group (mean age = 31 +/- 6 years) and the large lesion group (mean age 53 +/- 24.2 years). Female predilection (male/female ratio 1:1.5, 1:2.75.) was more significant in patients with large lesions. No statistically significant differences were found in systemic health score (mean American Society of Anesthesiology score 1.39, 1.53). Oral hygiene score (percent calculus 78% +/- 3.1%, 95% +/- 2.7%, percent gingival bleeding 58% +/- 3.6%, 73% +/- 5.4%, percent deep pocket 30% +/- 2.8%, 42% +/- 3.1) was better among the patients with small lesions. The percentage of patients with a report of oral dryness was significantly higher (3.1%, 27%) among patients with large lesions. CONCLUSIONS: Findings from this study suggest that patients with large (> 2 cm) peripheral giant cell granuloma lesions are more likely to be women with lower oral hygiene scores and xerostomia. Further studies are required to measure the relative risk of these factors.

Adult↗

Teeth in the maxillary sinus--imaging and management.

PURPOSE: To evaluate the images obtained by CT in diagnosis and treatment plan of teeth in the maxillary sinus. METHODS: Twelve patients with teeth in the maxillary sinus were studied by plain film radiography (PFR) and by CT with a dental software programme, which displays multiple panoramic and cross-sectional views of the mandible and maxilla. The three-dimensional morphology of the tooth, its inclination, proximity to the sinus wall, surgical planning and prediction of prognosis and complications were estimated on both PFR and on CT scans and scored. RESULTS: The radiographical features interpreted from PFR were fair or poorly diagnosed whereas CT provided excellent features. The surgical approach of choice was based on CT interpretation. CONCLUSION: CT is useful for diagnosis and treatment planning of teeth in the maxillary antrum.

Adult↗

Ehlers-Danlos syndrome, fibromyalgia and temporomandibular disorder: report of an unusual combination.

An unusual case of temporomandibular disorder in the presence of both fibromyalgia and Ehlers-Danlos syndrome is presented. Some of the problems in treating these patients are discussed. It is suggested that early conservative treatment of the temporomandibular disorder with a stabilization splint and physical therapy is effective, and this approach should be attempted before any surgical intervention is chosen.

Adolescent↗