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Biomedical subjects

L Berg

Publications and source records attributed to L Berg.

120 records · Page 7Linked to original sources
PubMed1975

An evaluation of alcoholism treatment services for Alaskan natives.

Using chart-review procedures, the authors examined the management of patients with a recognized alcohol problem in 12 medical facilities and 20 alcoholism programs throughout Alaska. The evaluation, which covered a one-year period, focused on the service delivery system rather than on treatment outcome, and sought to determine if problems of alcohol abuse were being solved. The authors found that a treatment plan was developed, followed up, and evaluated for 8 per cent of the problem drinkers treated in medical facilities and for 16.7 per cent of those in alcohol programs.

Alaska↗
PubMedDate not supplied

Demonstration of the role of prostate-specific antigen in semen liquefaction by two-dimensional electrophoresis.

Two-dimensional protein profiles of human semen, prostatic fluid, and seminal vesicle fluid were compared to demonstrate changes in the protein composition of human semen before and after liquefaction. Semen specimens were obtained from a volunteer. Prostatic fluid specimens were collected by rectal massage from patients visiting a urology clinic. Samples of seminal vesicle fluid were collected by needle aspiration from isolated seminal vesicles, which were removed at surgery. All specimens were prepared and processed according to the ISO-DALT system for separation of proteins in two-dimensional gels. Following electrophoresis, protein spots in the gels were visualized by silver staining. Prostatic fluid and seminal vesicle fluid showed their characteristic protein profiles. The protein profile of human semen contained specific proteins of both prostatic fluid and seminal vesicle fluid. One major group of proteins in seminal vesicle fluid (Mw 28,000-68,000 daltons), designated as seminal vesicle-specific antigen, was observed in freshly ejaculated human semen, but disappeared from the two-dimensional profile when the ejaculate was allowed to stand at room temperature for 30 min. When prostatic fluid or prostate-specific antigen was mixed with seminal vesicle fluid and incubated at 37C for 30 min, the seminal vesicle-specific antigen also disappeared from the two-dimensional profiles. The findings indicate that seminal vesicle-specific antigen, a group of predominant proteins in seminal vesicle fluid, is the structural component of seminal coagulum, and that prostate-specific antigen is the enzyme which digests seminal vesicle-specific antigen and liquifies semen coagulum.

Adult↗
PubMedDate not supplied

Correlation of computed tomographic and histopathologic features in malignant transformation of benign mixed tumor of lacrimal gland.

A 65-year-old man had painless progressive proptosis of five years' duration in his left eye. Sudden increase of the proptosis required a lateral canthotomy. A lateral orbitotomy was performed and a large, encapsulated, globoid mass was totally excised. Histopathologic diagnosis was adenoid cystic carcinoma arising in and surrounding a benign mixed tumor of the lacrimal gland. The computerized tomographic features correlated quite accurately with the gross appearance and histopathologic findings observed in the lacrimal gland mass. The authors discuss the clinical and radiographic features that should alert the clinician to the possibility of malignant transformation in a benign mixed tumor of the lacrimal gland.

Aged↗
PubMedDate not supplied

Factors associated with residents' attitudes toward dying patients.

BACKGROUND AND OBJECTIVES: Management of the dying patient often elicits anxiety in physicians. This study identified the association of physicians' personal fear of death, tolerance of uncertainty, and attachment style with physician attitudes toward dying patients. METHODS: Four psychological scales were distributed to family practice residents located in Texas, Missouri, and Maine. The scales were "Death Anxiety," "Death Attitudes," "Physicians' Reactions to Uncertainty," and "Experiences in Close Relationships." The scores from the measures and demographic data were used to determine which factors were associated with physician attitudes toward caring for terminally ill patients. RESULTS: Completed surveys were received from 157 residents. Younger residents (< 30 years) reported more stress from uncertainty and were more uncomfortable with the care of dying patients. Residents who reported higher death anxiety were also more uncomfortable with caring for dying patients. In a multivariate analysis, uncertainty, death anxiety, and age predicted 26% of the total outcome variance of the death attitudes score. CONCLUSIONS: Physician tolerance of uncertainty plays a significant role in physician attitudes toward the dying patient. Our findings suggest that decreasing physicians' stress from uncertainty by educating them in the management of the dying patient may improve their attitude toward death and may better prepare them to provide end-of-life care.

Adaptation, Psychological↗
PubMedDate not supplied

Brain atrophy in dementia judged by CT scan ranking.

In order to further investigate the relationships of brain atrophy, age, and dementia, computed tomographic (CT) scans on two groups of subjects aged 65-80 years were rank-ordered according to ventricular and sulcal size. Each group contained subjects with mild senile dementia of the Alzheimer type (SDAT) and matched controls. In both experiments there was a strong correlation between these rank orders, ventricular size, and the clinical dementia rating. There was also a weaker but significant correlation between rank ordering and sulcal size. This suggests that brain atrophy in excess of that normal for age alone occurs in early SDAT.

Aged↗