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Biomedical subjects

L Berardinelli

Publications and source records attributed to L Berardinelli.

At least 55 records · Page 3Linked to original sources

Outcome of renal grafts with multiple or damaged vessels.

We have examined a total of 708 donor kidneys for vascular abnormalities. Twenty-two point seven per cent of these had arterial damage or anomalies and in 11 per cent venous abnormalities were found. Five hundred and fifty-one of these kidneys were transplanted in our centre. Excluding 38 recipients of living related donor grafts there was a slightly higher incidence of re-operation and urological complications amongst the recipients of kidneys which had either required bench-top arterial microvascular surgery for vessels damaged at donor nephrectomy or which had multiple vessels. However, the function and actuarial graft survival of such kidneys differed little from those of kidneys transplanted with a conventional single arterial anastomosis.

Adolescent↗

[Postoperative jaundice in vascular surgery].

The Authors perform a retrospective study on the incidence of postoperative jaundice in a selected group of 2060 patients, who underwent operations of general or vascular surgery. The incidence of jaundice in the postoperative period appears to be quite high in vascular surgery: out of 96 patients became jaundiced, 78 were operated on for vascular diseases. A prolonged operation and multiple transfusions, besides the type itself of operation (general or vascular surgery) play important roles in this specific pathologic picture. The equality of anesthetic procedures employed makes the clinical study and statistical correlations significantly reliable.

Anesthesia, General↗

[Surgical treatment of renvascular hypertension. Personal cases].

Authors analyze a personal series of patients surgically treated for renal artery diseases (177 cases). Criteria of screening and diagnosis of stenosis are discussed and also are referred the clinical data. Authors describe their own personal reconstructive technique on renal arteries. Early and late results are widely analyzed.

Adolescent↗

Technical problems in living donor transplantation.

Inferior outcomes are generally described with grafts having multiple arteries or renovascular disease. A consecutive series of 261 living donor (LD) transplants performed in the CsA era was classified in three groups with regard to the graft arterial abnormalities and the techniques employed for revascularization. Two hundred eleven recipients had a kidney with one "healthy" renal artery (Group I); 11 patients, multiple arteries, which were reconstructed by various intracorporeal techniques (Group II); 39 patients, one diseased renal artery or multiple arteries, which were reconstructed on the bench (Group III). One- and 3-year graft survivals not censored for death, were 91%, 82%, 100% and 87%, 82%, 100%, respectively, for Group I, Group II, and Group III. An aggressive policy in performing microsurgical bench reconstruction, also for kidneys with one artery that are affected by intrinsic disease, allowed us to obtain a 3-year graft survival of 100% in our more recent consecutive series of 53 LD transplants.

Adult↗

Nosocomial infection in kidney transplant recipients: a retrospective analysis of a single-center experience.

Posttransplant bacterial infections are important because of their influence on patient and graft outcomes. Therefore, prevention of infection as well as prompt diagnosis and appropriate treatment are crucial. In this retrospective analysis, we reviewed all posttransplant bacterial infections occurring during the admission of kidney transplant patients from January 2000 to May 2004. Of our patients, 25% had at least one episode of infection. Patients with immunosuppression based on an mTOR inhibitor showed the highest rate of wound infections compared to those receiving a calcineurin inhibitor (odds ratio 5.6, P < .001). Patients with renal failure caused by a urologic disease revealed a increased risk of a urinary tract infections (odds ratio 5.9, P < .001). Although infection complications are an important cause of morbidity in renal transplantation, the extensive use of antibiotics should be avoided in favor of a strict policy for infection prevention and control.

Bacteremia↗

Value of intraoperative resistive index in kidney transplant.

The value of the resistive index (RI) obtained by echo color doppler evaluation of the transplanted kidney is still not well established. Many authors consider the RI to be nonspecific sign of rejection, acute tubular necrosis, or urinary tract obstruction, but its specificity remains low. In this paper, we report our experience with RI determinations in 34 consecutive kidney transplants at different times namely: perioperatively, at 24 hours, at 3 days, at 6 and at 9 days posttransplant. In all patients intraoperative RI was normal. RI increased significantly after transplantation in 10 patients who eventually developed a complication: delayed function, acute rejection, and spontaneous kidney ruptures. This increment from the baseline value was already significant at 24 hours after the kidney transplant, indicating a possible posttransplant complication (0.62 +/- 0.07 vs 0.76 +/- 0.04; P = .0004). We conclude that the value of RI in the early posttransplant phase should be considered an important aid for the early diagnosis of posttransplant complications.

Adolescent↗