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Biomedical subjects

L Benýsek

Publications and source records attributed to L Benýsek.

At least 19 recordsLinked to original sources
PubMed1983

[Constipation].

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Constipation↗
PubMed1982

Malignant lymphomas primarily involving the gastrointestinal tract.

Primary gastrointestinal lymphoma (PGIL) develops mostly on the basis of lymphoplasmocellular infiltration following an alteration of gastric or intestinal mucosa; its evolution is enhanced by a simultaneous defect of cell-mediated immunity. The paper deals with clinical, biochemical and immunological findings observed in 22 patients with PGIL during a course of 10 years. Some illustrative patient summaries are reported in a more detailed description. In histological terms, the cases were classified according to the Kiel classification. There seems to be an unfavourable prognosis of the disease, the average survival being about 10 months and cytostatic treatment is not tolerated well. The particular features of PGIL important for the diagnosis and treatment are pointed out.

Adolescent↗
PubMed1982

Increased serum beta-2-microglobulin level in patients with inflammatory bowel disease.

Beta-2-microglobulin (B2m) serum levels were measured by newly developed electroimmunoassay in a group of patients with inflammatory bowel disease. Increased serum B2m concentrations were found in 66.7% out of 93 subjects with Crohn's disease and in 56.0% out of 25 subjects with idiopathic proctocolitis. According to the author's view, serum B2m can be regarded as a useful adjunct to other immunological markers in diagnostic evaluation and monitoring of Crohn's disease. The high B2m level may reflect elevated biosynthesis and release from immunologically activated lymphocytes in areas of inflammation.

Adult↗