Drugs and breast feeding.
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Biomedical subjects
Publications and source records attributed to L Beeley.
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Seven thousand five hundred and twenty-six prescriptions written for eight hundred and forty patients in three hospital wards have been analysed for errors of drug use and errors of prescription writing. 2. According to the criteria adopted for this survey, more than 3% of prescriptions contained an error of drug use and more than 30% an error of prescription writing. 3. The incidence of adverse drug reactions, overdosage and undertreatment might be reduced by more careful prescribing.
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Glomerular filtration rate was measured from the plasma disappearance curve after a single injection of sodium (125)I-diatrizoate. A therapeutic dose of aspirin in 13 subjects produced a mean fall in glomerular filtration rate of 10.5%.
Fucidin is useful against ;antibiotic-resistant staphylococci' which are a major problem in causing shunt site infections in patients on chronic intermittent haemodialysis for end-stage renal failure. A new form of intravenous fucidin has been used in vivo in three patients on haemodialysis, and also in experiments in vitro in order to assess its dialysing properties. The experiments in vitro show that some fucidin does cross the dialyser membrane but, in the patients studied, adequate serum levels were maintained throughout a 10-hour haemodialysis. A single intravenous dose of Fucidin is, therefore, adequate for treating ;antibiotic-resistant' staphylococcal infections in patients during haemodialysis.
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