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Biomedical subjects

L Beecher

Publications and source records attributed to L Beecher.

4 recordsLinked to original sources
PubMed1993

Shifts and awakenings: valuable indicators of the quality of sleep: do these parameters react differently to hypnotics?

In order to test the assumption that the sleep stability increases as the number of shifts and awakenings decreases, all-night sleep recordings (registered at home) were reanalyzed. The registrations belong to 10 young good sleepers, 10 adult good sleepers, 10 insomnia patients without treatment, 10 treated with a benzodiazepine and 10 treated with a nonbenzodiazepine hypnotic, 10 patients with proven narcolepsy, and 10 with obstructive sleep apnea syndrome (OSAS). For each of the categories NREM-1-2, NREM 3-4, and REM sleep, indices were defined as the number of shifts and awakenings that occurred per hour. Our results show that the indices of awakenings for the good as well for the bad sleepers were similar, whereas the indices of awakenings were very group dependent. We interpreted these results as showing that awakenings are valuable indicators for studying the quality of sleep, whereas shifts are not.

Adolescent↗
PubMed1989

Short-term effects of temazepam in the EEGs of healthy volunteers.

In this study effects of temazepam on the EEGs of 10 healthy volunteers were detected using a standardized EEG registration procedure applied in a controlled environment. The EEGs were recorded both before and after administration of 20 mg temazepam as well as before and after placebo. A mean power spectrum was computed for each EEG from the 'eyes closed' condition, and the Student t test was used to detect differences in the spectra of the pre- and posttreatment EEGs in both placebo and drug conditions. For all 10 subjects the drug condition was easily distinguishable from the placebo condition based on the results of the t test.

Adult↗