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Biomedical subjects

L Barta

Publications and source records attributed to L Barta.

At least 55 records · Page 3Linked to original sources

The influence of physical exercise upon the body composition of obese children.

Thirty-seven obese children 8 to 14 years of age were given a diet 115 kJ/kg of ideal weight for height and were distributed in two groups. One group was under normal ward conditions and the other underwent a physical exercise programme. Body weight, the percent of ideal weight referred to height, percent body weight, and absolute body fat were determined before and 15 days after both therapeutic regimes. The results revealed significant differences in the reduction of these parameters (p < 0.001). When comparing the two groups, only the reduction of percent body fat displayed a significant difference (p < 0.02), showing a greater reduction in those who had performed physical exercise.

Adolescent↗

Inheritance of childhood diabetes.

In the parents of 250 diabetic children the occurrence of juvenile and maturity onset diabetes was found to be more frequent than in the parents of 230 medical students. Assuming a multifactorial poligeneic heredity, the role of common genes predisposing to diabetes cannot be neglected in the manifestation of the two types of the disease. In the families where juvenile diabetes had occurred, the probability of occurrence of juvenile diabetes is considerably higher than that of maturity onset diabetes. This might be in connection with the fact that the provocative factors are different in juvenile and maturity onset diabetes.

Adolescent↗

[Evaluation of evidential data of diabetic children (author's transl)].

On the basis of the evidential data of 365 children with diabetes mellitus the interrelation between certain data and the manifestation of the diabetes mellitus has been examined. There is a positive correlation between the birth weight and the body length observed at the manifestation. The number of extremely tall children is higher than expected with regard to the population. Equally, the age of parents at the time of birth of their diabetic children is relatively higher when compared to the average of the population. In addition, there are seasonal changes; the most frequent manifestation of diabetes is seen in the months January and October, and--surprisingly--is lowest in May.

Adolescent↗

Dermatoglyphic features in diabetes mellitus.

Dermatoglyphic features of 290 children and 180 adults with diabetes mellitus were investigated. WD occurred significantly more frequently on the fingers, and pattern intensity was low in certain interdigital areas in these patients. A high TRC value was more frequent in both girls and boys with diabetes mellitus than in the controls.

Adolescent↗

HLA B8 and BW15 antigens in diabetic children.

The simultaneous occurrence of HLA B8 and BW15 and B8 antigens is significantly more frequent in diabetic children than in the general population. BW15 alone shows no significant difference but may be considered as a potentiating factor. The relative risk of the manifestation of diabetes in the highest when HLA B8 and BW15 occur simultaneously. In the nearest diabetic relatives of diabetic children the occurrence of B8 and B8 and/or BW15 antigens is significantly more frequent than in the diabetic child population.

Adolescent↗

[Simultaneous occurrence of juvenile diabetes and Addison's disease (author's transl)].

The occurrence of diabetes mellitus and Addison's disease together is discussed by the authors. The female patient described here had diabetes at the age of four; Addison's disease appeared when the patient was 19 years old. Four years prior to the appearance of Addison's disease, an ophthalmoscopic examination revealed microaneurysms. The examination of the fundus of the eye was negative when Addison's disease, was diagnosed. An HLA-B8 antigen positivity was established. The authors discussed the pathogenetic relationship of HLA-B8 antigen positivity, diabetes mellitus, and Addison's disease.

Addison Disease↗

Effect of insulin on serum lipids in juvenile diabetes.

In diabetic children, the effect on serum lipids of insulin by itself and combined with glucose of with Aminosol + glucose has been studied. The level of serum free fatty acids decreased significantly in every case. The cephalin level decreased under the effect of insulin and insulin + Aminosol, whereas it rose after insulin and glucose infusion. The triglyceride level remained unchanged when insulin was applied by itself, and decreased significantly under the effect of insulin + Aminosol, while it showed a rising tendency after insulin + glucose infusion.

Adolescent↗

[True hermaphroditism with 46, XY/46, XX/47 XXY mosaicism (author's transl)].

A case of true hermaphroditism was described. The patient had an uterus, a fallopian tube, a testide on the left in the position of the ovary and an ovary on the right side. The chromosome picture corresponded to a 47, XXY/46, XX/46 XXY mosaic. The phenotype of the patient was male so the decision for male sex seemed to be justified.

Adult↗

[Early diagnosis of microangiopathy in infantile diabetes (author's transl)].

The authors have carried out fluorescein angiography in infantile diabetics--negative by ophthalmoscopy,--looking for the earliest symptoms of microangiopathy. The study concerned 161 diabetics in the age between 3-18, and 50 non-diabetic children in the same age. There is no significant difference between diabetics and control-group in the frequency of symptoms, described in literature as early signs of microangiopathy, as multiple capillary-, and peripapillary-filling and early venous dilatation. Increased capillary filling was found at anxious children with strained cervical muscles during the examination. In 54% of the 161 diabetic patients-negative by ophthalmoscopy,-solitary or multiple microaneurysms were found fluorescence angiographically. The increase of number of the microaneurysms is correlated to the duration of the diabetics and advance in age. In the authors opinion the presence of microaneurysms is in some cases due to genetic factors and is independent from the metabolic changes of diabetes.

Adolescent↗

Sugar metabolism in obese children.

In obese children the glucose tolerance curve results in high blood sugar values. A pathologic rise of the serum insulin level may occur even with normal blood sugar curves and the insulin levels tend to be higher in obesity of long standing. In obese children of families with diabetes, post-loading insulin levels were comparatively lower. It is suggested that this weaker insulin response is related to a prediabetic state.

Adolescent↗