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Biomedical subjects

L Baert

Publications and source records attributed to L Baert.

At least 199 records · Page 11Linked to original sources
PubMed1989

Pulmonary migration following periurethral polytetrafluoroethylene injection for urinary incontinence.

We report a case of clinically significant migration of polytetrafluoroethylene (Teflon) paste particles to the lungs after periurethral injection. These particles were identified by standard and polarized light microscopy. Since the long-term effects in humans are not sufficiently known, we strongly warn against the use of polytetrafluoroethylene paste in children or young adults with a normal life expectancy.

Adult↗
PubMed1989

Prepubic urethrectomy.

Explore the source record for details and available documents.

Carcinoma, Transitional Cell↗
PubMed1989

Amoxycillin/clavulanate prophylaxis for extracorporeal shock wave lithotripsy--a comparative study.

The incidence of urinary tract infection was examined in 181 patients with sterile urine who underwent extracorporeal shock wave lithotripsy (ESWL) as outpatients. The incidence of post operative infection was compared in a prospective randomized trial between patients who received a single prophylactic dose of amoxycillin/clavulanate iv and controls who received no antibiotic. Clinical signs of urinary infection, leucocyturia, positive urine cultures and abnormal ESR and peripheral leucocyte count were found much more frequently in the control than in the prophylactic group. This study has confirmed that even patients free of infection risk factors benefit from antibiotic prophylaxis before ESWL.

Adult↗
PubMed1989

Extracorporeal shock wave lithotripsy and cardiac arrhythmias.

Holter monitoring was performed in 400 patients undergoing extracorporeal shock wave lithotripsy (ESWL). The highest heart rate occurred before and after ESWL. During respiratory-triggered ESWL, 30% of the patients had one or more ventricular premature beats (VES), and 7% had couplets of VES. The number of ventricular and supraventricular premature contractions was significantly lower during ECG-triggered ESWL. Ventricular tachycardia occurred in seven patients during respiratory-triggered ESWL, and in one patient during nontriggered ESWL. All ventricular tachycardias were nonsustained, asymptomatic, and slow. Supraventricular tachycardia was seen in nine patients. The preference of the urologist for respiratory-triggered ESWL, conflicts with its higher incidence of ventricular arrhythmias.

Adult↗
PubMed1989

Second-generation lithotripsy: a safe, noninvasive, ambulatory procedure.

A total of 600 patients underwent 696 treatments of extracorporeal shockwave lithotripsy (ESWL) during the period between June and November 1987. Our progressively increasing experience with the second-generation device shows that this new unit is as effective as the conventional one, and reveals several advantages. The focusing of the stone is easier; therapy time is shorter; general or regional anesthesia is no longer necessary; distal ureteral stones can be disintegrated, and adjuvant procedures are easily performed during the ESWL session. Of the last 400 patients of our series, 76% were treated on an outpatient basis without any major complications.

Ambulatory Care↗
PubMed1989

Transcutaneous nitroglycerin therapy in the treatment of impotence.

In order to avoid the side effects and drawbacks of intravenous injection of vasoactive drugs, we evaluated the use of transcutaneous nitroglycerin, a powerful smooth muscle relaxant, in enhancing the quality of erection. In this study, 26 impotent patients were treated with (nitroglycerin or placebo) patches applied to the skin of the penile shaft. A positive response was reported by 21 patients and 17 men out of the 21 were able to distinguish a marked difference between the nitroglycerin and placebo patches. These results indicate that nitroglycerin patches have to be tried, especially in patients with moderate erection disturbances.

Administration, Cutaneous↗
PubMed1989

Neuropathological examination of the alterations of the intrinsic innervation in multiple sclerosis cystopathy.

Morphometric analysis of the innervation pattern of the stromal layer of the urinary bladder was done on biopsies from 88 patients with definite multiple sclerosis (MS). The biopsies were stained for acetylcholinesterase and for S100 protein, and a semiquantitative score was assigned. Nearly 30% of the samples showed increased immunoreactivity for S100, indicating Schwann cell hyperplasia. In 16% a decreased S100 immunoreactivity was found, the significance of which is unclear. More than 90% had normal acetylcholinesterase activity. No correlation could be demonstrated for age, sex, severity and duration of the disease, the presence of cystitis and type of detrusor dysfunction. The finding of altered S100 immunoreactivity in MS bladders could indicate that MS also affects the peripheral nervous system and is not limited to the central nervous system as classically described. This finding warrants further investigations.

Acetylcholinesterase↗
PubMed1989

[Innervation density in the stroma and the muscular tunica in biopsies of the normal and pathologic bladder].

Twenty-eight open urinary bladder biopsies were stained using a peroxidase-antiperoxidase technique for S100 to demonstrate the innervation pattern in three different patient groups. The nerve profiles in the subepithelial stroma and in the musculosa were counted and compared. There was a definite correlation between nerve density in both layers. Examination of superficial bladder biopsies is reliable in the assessment of the innervation pattern of neurogenic and non-neurogenic bladder disorders.

Aged↗
PubMed1988

Clinical experience with ciprofloxacin in the treatment of urinary tract infections: a review.

During the clinical development of ciprofloxacin 1,519 treatments of UTI were documented. The most frequent specific diagnoses were uncomplicated UTI (46.6%), followed by non-specified UTI (21.7%), complicated UTI (19.4%), acute pyelonephritis (7.6%) and chronic pyelonephritis (4.1%). 70% of the causative organisms isolated were Enterobacteriaceae (Escherichia coli 38%, Proteus spp. 10% and Klebsiella pneumoniae 10%). Pseudomonas aeruginosa occurred in approximately 20% of the cases and the remaining 10% were gram-positive aerobes. Clinical resolution was achieved in about 90% in all specific diagnoses. The eradication rate for gram-negative Enterobacteriaceae was 93.8%, for P. aeruginosa 81.8% and for gram-positive aerobes 90.2%. Studies comparing ciprofloxacin and standard treatment have shown the high efficacy of ciprofloxacin making it a preferred agent particularly for infections caused by pathogens less susceptible to conventional drugs. According to the experience of clinical trials the recommended ciprofloxacin dose varies between 100 and 500 mg b.i.d. orally depending on the severity of clinical status and the susceptibility of the pathogen.

Adult↗
PubMed1988

Intraarterial embolization in combination with surgery in the management of congenital pelvic arteriovenous malformation.

A case of congenital arteriovenous fistula of the pelvis is described. Arteriovenous malformations of the pelvis are rare and can give rise to problems in diagnosis and treatment. A long history of vague complaints precedes determination of the correct diagnosis. Because recurrence is not uncommon after treatment, intraarterial embolization in combination with surgery is mandatory.

Adult↗
PubMed1988

Chronic bacterial prostatitis: 10 years of experience with local antibiotics.

Direct transperineal infiltration of the prostate with antibiotics was performed in 24 selected patients with refractory chronic bacterial prostatitis. Diagnosis had been made following a modification of the classical lower tract localization studies. Remission periods of at least 6 months were obtained in 71 per cent of these patients after 1 or 2 infiltrations, while 6 of 24 (25 per cent) required several procedures to assume a long-term remission state and 1 (4 per cent) failed therapy (patient 24490). Seven patients had relapse after remission periods ranging from 13 months to 7 years. The last culture in 3 patients was positive. The value of the method compared to other therapeutic alternatives in the management of chronic bacterial prostatitis is discussed.

Adult↗
PubMed1988

Histochemical assessment of the intrinsic innervation of the normal urinary bladder.

In order to assess the normal intrinsic innervation pattern, an enzyme histochemical acetylcholinesterase and two immunohistochemical (S100 protein and neurofilaments) stainings were done on 38 normal urinary bladder specimens. The nerve density was calculated as a mean number of nerve fibers counted per high power field. S100 staining after adequate fixation proved to be similar to the acetylcholinesterase technique, avoids freezing manipulation, is easier to read and permits normal conventional histological examination. Neuropathology of bladder biopsies is an easily available diagnostic method in current neurourological practice.

Acetylcholinesterase↗
PubMed1988

Vasoactive intestinal polypeptidergic innervation of human urinary bladder in normal and pathological conditions.

Urinary bladder biopsies from 31 multiple sclerosis patients, 9 diabetics, 5 patients after transtrigonal phenolization and 20 control patients were stained for acetylcholinesterase, S100 and vasoactive intestinal polypeptide (VIP). The VIP immunoreactivity was not decreased in all neuropathic bladders and its depletion was not related to cholinergic depletion. There was no correlation between bladder over- or underactivity and VIP content. VIP can act as a modulator of detrusor function in normal conditions. The significance of its depletion in neurogenic bladders needs further elaboration.

Acetylcholinesterase↗