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Biomedical subjects

L B Jaques

Publications and source records attributed to L B Jaques.

At least 91 records · Page 5Linked to original sources
PubMed1965

Hemostasis as a total physiological function.

The hemostasis is due to the combined action of several systems, blood composition, blood flow and vessels. The author reviews the factors which determine the vessel integrity and promote the repair after trauma.

Blood Circulation↗
PubMedDate not supplied

Effect of intrapulmonary heparin on lipoprotein lipase activity in mice.

The lipoprotein lipase (LPL) activity obtained from the intrapulmonary administration of 2-10 mg of heparin in mice was compared with the same parameter measured for intravenously administered heparin. The doses administered were based on appropriate clinical equivalents. A relatively large dose of intrapulmonary heparin produced a peak LPL activity which was a third of the maximum response obtained from a small dose of i.v. heparin. This was followed by a moderate LPL activity (twice the control level) which persisted for the next 4 days while the response obtained from i.v. administered heparin lasted only 2 h. Both the intrapulmonary and the i.v. administration of heparin produced dose-dependent increases in plasma LPL activity (correlation coefficient r = 0.9). This study indicates that intrapulmonary heparin causes a prolonged antilipemic effect.

Animals↗