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Biomedical subjects

L Arisi

Publications and source records attributed to L Arisi.

At least 37 records · Page 2Linked to original sources

Vascular stability and middle molecules removal in hypertonic haemodiafiltration.

Hypertonic haemodiafiltration is a simultaneous hypertonic (delta 550, Na 275mEq/L) low volume (7.2 litres) haemofiltration and hypotonic (delta 282) short time (180') haemodialysis. Reduction of the predialysis body pool of MM (-48 per cent) and small molecules (-33 per cent) was obtained. No relationship between vascular stability and MM removal was observed. However, a net UF of 20.5ml/min and a greater removal of solutes up to 1500 daltons mw were obtained with a three hours thrice weekly dialysis programme.

Anuria↗

Critical appraisal of haemofiltration and ultra-filtration. The development of ultra-short dialysis: preliminary results.

The clinical experience obtained with 2 hours every other day recirculation dialysis, using 20-40 liters of dialysate, without sorbents, and standard cuprophane dialyzers of 1.0-1.5 sq.mt. is reported. So far, over 350 treatments in 8 patients have been performed. After 2 hours of treatment the removal of urea, creatinine, phosphate and uric acid, is similar to that obtained by 4-6 hours of haemofiltration. The alkalinazation of the patient through direct venous infusion of bicarbonate, makes predialysis acid-base significantly better than in standard haemodialysis and haemofiltration. Asymptomatic correction of severe fluid overload is easily obtained like in isolated ultrafiltration. The role of osmolality and vasopressors are discussed. A dry weight below the value obtained by previous dialysis treatment is achieved, and volume dependent hypertensions as in haemofiltration are corrected after 2-8 weeks. As an additional advantage, this method offers a highly semplified technical approach and a further reduction of the dialysis time.

Bicarbonates↗

[Notes on a case of clinostatic chyluria].

A clinical case of clinostatic chyluria of unknown non-parasitic aetiology, is reported. Ascending pyelography showed the presence of lymphatic communications between right renal pelvis and homolateral lumbo-aortic lymph nodes. Aetiology, pathogenesis, prognosis and diagnostic tools of use in the syndrome are discussed. The problem of the possible lymphatic origin of benign proteinuria, in relation to anatomic considerations and to quality and quantity resemblances between individual protein fractions in chyluria and benign proteinuria encountered in the present case, is also discussed. In order to clarify the problem, emphasis is laid on the advisability of simultaneously studying urinary protein composition in postural chyluria and lipid composition in benign proteinuria.

Chyle↗

Short dialysis schedules (SDS)--finally ready to become routine?

One hundred and one patients were treated for up to two years for three hours every other day (10.5 hr/week), or four hours thrice-weekly with conventional disposable 1m2 dialysers have been investigated. Rigorous control of water balance and the maintenance of predialysis serum K and PO4 within normal limits were the main criteria for judging the adequacy of the treatment. The results regarding blood pressure, phosphate problems, haematocrit, peripheral nerve status, pericarditis and range of rehabilitation are discussed.

Adolescent↗

[Oral and i.v. iron therapy in haemodialysis patients (author's transl)].

Low serum iron level with a transferrin saturation below 16% is a crucial aetiologic factor of anaemia in haemodialysed patients. Current therapy usually is a correct dialytic and dietetic treatment and i.v. iron supply. Two groups of haemodialysis patients with low serum iron but a normal transferrin saturation, have been studied by comparing the efficacy of the i.v. and the oral iron supply. The serum iron of the two groups changed from low to normal level with highly significant difference. Haemoglobin and haematocrit did not change because of the normal transferrin saturation before the treatment. In conclusion, in uraemic patients treated by chronic dialysis, the oral and the i.v. iron therapy probably give the same result.

Administration, Oral↗

Preliminary results obtained with short dialysis schedules.

The results regarding the treatment of 55 patients, 6 of them treated for, at least 10 months, with 1 sq. meter disposable dialyzers and a dialysis strategy of 3 hours every other day or 4 hours trice weekly have been presented. Clinical indexes especially regarding erythropoiesis and peripheral nerve status will be discussed. Th results show that this new method of treatment is feasible and may become in the future a routine strategy for chronic intermittent dialysis.

Adult↗

[Adherence to dietetic treatment, the nutritional metabolic status and the progression of chronic kidney failure].

Effects of two protein restricted diets on dietary compliance, nutritional and metabolic state, and progression of chronic renal failure (CRF) were investigated. Twenty-one patients with CRF were randomly assigned to either a conventional low protein diet (0.6 g of protein/kg b.w./day) or to a very low protein diet, providing 0.4 g of protein/kg b.w./day, supplemented with a mixture of essential amino acids which contained HIS, TYR and a high proportion of branched chain amino acids. Nutrition, assessed by body weight, anthropometry, serum protein levels and nitrogen balance studies, was maintained in all patients. Some metabolic abnormalities of CRF (i.e., secondary hyperparathyroidism, glucose intolerance) improved in both groups. The supplemented diet provided better adherence to protein prescription, corrected the depletion of VAL and LEU in muscle and was more effective than conventional diet in slowing the rate of progression of CFR.

Adult↗