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Biomedical subjects

L Alcidi

Publications and source records attributed to L Alcidi.

3 recordsLinked to original sources
PubMed1978

Preliminary experience with the pH-triggered pacemaker.

A cardiac pacemaker capable of responding to blood acidosis by change in its stimulation rate allows adjustment to a patient's metabolic needs. The blood pH is sensed by an iridium oxide electrode in the right atrium. During exercise, the venous pH decreases and the paced ventricular rate increases. If acidosis persists, the paced rate gradually returns to baseline and reaches it after about 70 minutes. A pH-triggered pacemaker has been implanted in a 72-year-old male. The pacemaker remained responsive one year after implant, increasing rate during exercise, cold pressor stress, ischemia of the arms and emotional stress.

Aged↗
PubMed1978

[Clinical and biological aspects in patient with pH-triggered implanted pacemaker (author's transl)].

The Authors have selected the variations of blood pH to drive the pacing rate according to the new biological balance created by exercise. The clinical tests performed on the patients who have had a pH-triggered pacemaker implanted one year previously demonstrated that: a) during physical exercise there is an increase of cardiac rate triggered by the pacemaker, comparable with that noted when sinus rhythm is present; b) situations causing an increased production of cathecolamines and thus a pH variation--Cold Pressor Test, Ischaemic Test, as well as emotional stress--cause an increase of the stimulation rate of pH triggered pacemaker.

Blood↗