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Biomedical subjects

L A de Santos

Publications and source records attributed to L A de Santos.

9 recordsLinked to original sources

Traumatic pseudoaneurysm of the anterior tibial artery simulating soft tissue malignancy.

Two patients presenting with false aneurysm of the anterior tibial artery are illustrated. Presentation was remote from the time of trauma and the diagnosis of neoplasm was initially considered in both because of the bony and soft tissue changes. The purpose of this report is to bring attention to the possibility of delayed vascular injury simulating tumor by describing the radiographic features of these two proven cases.

Aneurysm↗

Subtle early osteosarcoma.

Seven cases of osteosarcoma in their very early stage of development are presented. With the exception of two cases the tumors were overlooked in the first radiographic examination. Two cases demonstrated increased density, three revealed subtle erosion or lytic destruction, and one case had no definite abnormality in plain radiographs but the computed tomography was abnormal. The value of additional radiographic modalities is outlined. The necessity of a high degree of suspicion for early diagnosis of osteosarcoma is stressed.

Adolescent↗

Metastatic hepatic neoplasms: angiographic features of portal vein involvement.

Hepatic metastases produce a spectrum of angiographic alterations of the portal vein that mimicks that of primary liver neoplasms. In 11 patients with varied primary malignancies, hepatic arteriograms revealed seven instances of opacification of the portal vein from arterioportal shunting, two cases of intraluminal tumor thrombus, and two cases with intrahepatic portal vein occlusion. Another patient with liver metastases developed an arterioportal fistula following percutaneous liver biopsy. Although uncommon, metastatic involvement of the portal vein is not necessarily indicative of a poor prognosis since one patient's arterioportal shunting resolved following intraarterial chemotherapy infusion and tumor regression.

Adult↗

Radiographic aspects of massive bone osteoarticular allograft transplantation.

Experience with 56 cases of osteoarticular allograft transplantation of the extremities is presented. Cadaveric allograft including a joint surface and a variable amount of shaft is used in the treatment of aggressive benign and low-grade malignant tumors involving a long bone near a joint. The preoperative radiographic evaluation is outlined. Thirty-four patients had an uncomplicated course. Twenty-two patients had complications including aseptic fracture, infection, and tumor recurrence. The radiographic spectrum of both complicated and uncomplicated cases is illustrated.

Adolescent↗

Radiographic findings of Ewing's sarcoma of the jaws.

The radiographic findings in eight cases of Ewing's sarcoma of the jaws are analysed in detail. Similar findings to those in peripheral skeletal involvement were demonstrated including: (a) permeative bone destruction, (b) periosteal reaction, and (c) extraosseous soft tissue mass. Specific to the jaws is the occurrence of dental displacement without destruction. The differential diagnosis of Ewing's sarcoma of the jaws is discussed in detail and illustrated.

Adolescent↗

Prostaglandin E1 (PGE1) in angiography of tumors of the extremities.

Prostaglandin E1 (PGE1) is a potent vasodilator. The value of this agent as an adjuvant in angiography of tumors of the extremities was evaluated in 10 patients. Except in one case involving a hemangioma, the diagnostic information concerning tumor vascularity and delineation of the extent of disease decreased after the use of PGE1. The visualization of small normal muscular arteries was improved. Therefore, the effect of PGE1 may be to preferentially increase the blood flow in normal tissues relative to the tumor. PGE1 seems to be of little value in enhancing the angiographic demonstration of neoplasms of the extremity.

Adolescent↗

Spiculated periosteal reaction in metastatic disease resembling osteosarcoma.

Sixteen cases of metastatic bone deposits presenting with sunburst spiculated periosteal reaction are presented. The most common origin was from prostatic carcinoma followed by neuroblastoma. A moderate soft tissue mass component was seen in 70% of the cases. The possible pathophysiologic reasons for this type of periosteal reaction are presented. The differential diagnosis is outlined.

Adenocarcinoma↗