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L A Stone

Publications and source records attributed to L A Stone.

At least 37 records · Page 2Linked to original sources
PubMed1990

Vitamin D receptors in intestine, kidney and thymus of streptozotocin diabetic rats.

Our data confirms previous reports of intestinal and kidney compensatory growth, low plasma 1,25(OH)2D3 and up regulation of intestinal VDRs during untreated diabetes. All of these parameters were normalized in diabetic rats treated with exogenous insulin. There were no alterations in VDR numbers in kidneys or thymus of untreated diabetic animals, indicating that up-regulation of VDRs during untreated diabetes did not occur in all vitamin D target tissues. Compensatory growth of the intestine during untreated diabetes was associated with both hypertrophy and hyperplasia, whereas diabetic kidney growth appeared to be associated with hypertrophy without hyperplasia. Diabetes did not affect somatic index of thymus. The data suggests that the up regulation of VDRs during untreated diabetes may be unique to the intestine and further that VDR up regulation may be related to hyperplasia. Calbindin D-9K was significantly lower in diabetic intestine, suggesting that low circulating 1,25(OH)2D3 prevented amplification of 1,25(OH)2D3's action despite up regulation of intestinal VDRs.

Alkaline Phosphatase↗
PubMed1984

Effect of technique variation on sensory nerve conduction characteristics.

The impact of technique variation on the wave-form characteristics of the evoked sensory potential was determined from the median and ulnar nerves of healthy subjects. The conduction characteristics of latency, amplitude, and duration were determined for orthodromic and antidromic techniques of stimulation as measured under each of three recording modes: 1) single evoked response, 2) superimposition, and 3) electronic averaging. Variation in the technique of stimulation significantly affected each of the three wave-form characteristics. Peak latency and duration of the evoked sensory potential were longer in antidromic stimulation. The amplitude of the sensory potential varied significantly with both recording and stimulating techniques. The amplitude of the sensory response was larger in antidromic stimulation than in orthodromic stimulation and also was found to be smaller with electronic averaging than with the other recording modes in both antidromic and orthodromic conduction techniques. This degree of variation requires that standardized techniques of methodology be established with the development of normal values for the particular laboratory.

Adult↗
PubMed1983

Contact dermatitis.

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Dermatitis, Contact↗
PubMed1975

Multidimensional scaling of pictorial informativeness.

The dimensions used in the judgment of the informativeness of picture sections were investigated by means of a recently proposed methodology, multidimensional similarity analysis. 10 judges (college students) rated the informational similarity of 32 areas within a single picture. The five extracted dimensions accounted for 86% of the judgmental variance and were all readily interpretable. These dimensions were discussed with respect to an earlier study in which eye movements of subjects viewing this picture were recorded.

Adult↗